BMTCN EXAM SCRIPT WITH VERIFIED
QUESTIONS AND ANSWERS
●● Red bone marrow produces
Answer: hematopoietic stems cells that create red blood cells, white
blood cells and platelets and is found in the long and flat bones
●● yellow bone marrow and fat cells produce
Answer: stromal stem cells that produce fat, cartilage and bone and are
found in the long bones.
●● hematopoietic stem cells develop
Answer: prior to birth and are produced in the long bones during
childhood and childhood and then the axial skeleton in adulthood.
●● bone marrow microenvironment
Answer: the bone marrow stroma is the housing unit and hub of cellular
activity.
●● components of hematopiesis
Answer: hematopoiesis stem cells
bone marrow microenvironment
cellular adhesions molecules
,chemokine, cytokines
●● the main objective of hematopoiesis is to
Answer: maintain the peripheral blood with the proper level of blood
components. the pluripotent stem cells mature and differentiate into the
myeloid progenitor cells within the bone marrow.
●● myeloid progenitor cells mature into
Answer: megakaryocytes (produce platelets)
erythrocytes
mast cells
myeloblasts
●● lymphoid progenitor cells mature into
Answer: small lymphocytes which differentiate into bone marrow-
derived cells (b cells) and thymus-derived cells (t cells)
natural killer (NK) cells
immune function is dependent on hematopoiesis
primary organs of the immune system are involved in the production,
maturation, and immune activity.
●● immune function is dependent on
Answer: hematopoiesis
,●● primary organs of the immune system are involved in the production,
maturation, and immune activity.
Answer: bone marrow
thymus gland
lymph nodes
spleen
●● thymus gland
Answer: located in the anterior mediastinum and forms t cells
●● lymph nodes
Answer: bean shape glands that cluster throughout the body in the neck,
chest, axillae, abdomen and inguinal region and function as an
immunologic filter.
●● spleen
Answer: the organ responsible for filtering white cells, platelets, and
other substances.
●● the immune system consist of
Answer: innate and acquired immunity.
, ●● innate immunity occurs
Answer: naturally and uses phagocytes that release inflammatory
mediator and NK cells.
●● acquired immunity
Answer: is the responsible of either B cells or T cells ti antigens
●● b cell activation can be
Answer: t-cell dependent or independent
●● hematopoiesis can be affected by
Answer: by senescence
●● senescence
Answer: loss of the cells power to divide and grow
●● hematopoietic stem cell senescence naturally occurs
Answer: with age but also is affected by cancer treatment and
transplantation.
●● immunosenescence
Answer: reduction in size of thymus and function of immune cells (not
necessarily a reduction in number)
QUESTIONS AND ANSWERS
●● Red bone marrow produces
Answer: hematopoietic stems cells that create red blood cells, white
blood cells and platelets and is found in the long and flat bones
●● yellow bone marrow and fat cells produce
Answer: stromal stem cells that produce fat, cartilage and bone and are
found in the long bones.
●● hematopoietic stem cells develop
Answer: prior to birth and are produced in the long bones during
childhood and childhood and then the axial skeleton in adulthood.
●● bone marrow microenvironment
Answer: the bone marrow stroma is the housing unit and hub of cellular
activity.
●● components of hematopiesis
Answer: hematopoiesis stem cells
bone marrow microenvironment
cellular adhesions molecules
,chemokine, cytokines
●● the main objective of hematopoiesis is to
Answer: maintain the peripheral blood with the proper level of blood
components. the pluripotent stem cells mature and differentiate into the
myeloid progenitor cells within the bone marrow.
●● myeloid progenitor cells mature into
Answer: megakaryocytes (produce platelets)
erythrocytes
mast cells
myeloblasts
●● lymphoid progenitor cells mature into
Answer: small lymphocytes which differentiate into bone marrow-
derived cells (b cells) and thymus-derived cells (t cells)
natural killer (NK) cells
immune function is dependent on hematopoiesis
primary organs of the immune system are involved in the production,
maturation, and immune activity.
●● immune function is dependent on
Answer: hematopoiesis
,●● primary organs of the immune system are involved in the production,
maturation, and immune activity.
Answer: bone marrow
thymus gland
lymph nodes
spleen
●● thymus gland
Answer: located in the anterior mediastinum and forms t cells
●● lymph nodes
Answer: bean shape glands that cluster throughout the body in the neck,
chest, axillae, abdomen and inguinal region and function as an
immunologic filter.
●● spleen
Answer: the organ responsible for filtering white cells, platelets, and
other substances.
●● the immune system consist of
Answer: innate and acquired immunity.
, ●● innate immunity occurs
Answer: naturally and uses phagocytes that release inflammatory
mediator and NK cells.
●● acquired immunity
Answer: is the responsible of either B cells or T cells ti antigens
●● b cell activation can be
Answer: t-cell dependent or independent
●● hematopoiesis can be affected by
Answer: by senescence
●● senescence
Answer: loss of the cells power to divide and grow
●● hematopoietic stem cell senescence naturally occurs
Answer: with age but also is affected by cancer treatment and
transplantation.
●● immunosenescence
Answer: reduction in size of thymus and function of immune cells (not
necessarily a reduction in number)
