NUR 265 EXAM 4 STUDY GUIDE 2026 | UNITS 9-11 | HIV/AIDS,
SLE, ORGAN TRANSPLANT, CANCER, CHEMOTHERAPY,
ONCOLOGY EMERGENCIES & DISASTER TRIAGE | GALEN
COLLEGE OF NURSING.
147 Questions with Answers and Detailed Rationales
100 PERCENT GUARANTEED PASS
INSTANT DOWNLOAD ANSWERS INCLUDED
IMPORTANCE OF THIS DOCUMENT
This comprehensive examination preparation guide has been meticulously developed to help you succeed in the
NUR 265 EXAM 4 STUDY GUIDE 2026 | UNITS 9-11 | HIV/AIDS, SLE, ORGAN TRANSPLANT, CANCER,
CHEMOTHERAPY, ONCOLOGY EMERGENCIES & DISASTER TRIAGE | GALEN COLLEGE OF NURSING.. It
contains 147 carefully selected questions that reflect the most current exam content and testing strategies. Each
question is accompanied by a correct answer and a detailed rationale that explains the underlying
pathophysiology, pharmacology, or clinical reasoning.
Self-Assessment – Test your knowledge and Exam Preparation – Familiarize yourself with the
identify areas requiring further question format and content
study areas
Concept Reinforcement – Deepen your Confidence Building – Develop test-taking
understanding through strategies and reduce
evidence-based exam anxiety
rationales
Time Management – Practice answering
questions under simulated
exam conditions
Review Summary 147 Questions
Foundations - Application - NUR 265 4 Study Guide 2026 Units 9 11 Hiv/aids SLE Organ Transplant
Cancer Chemotherapy Oncology Emergencies & Disaster Triage Galen College OF Nursing Nursing Complex
Health Alterations Hiv/aids SLE Organ Transplant Oncology Chemotherapy Oncologic Emergencies Disaster
Triage Undergraduate YEAR 3 BSN Galen College OF Nursing
All answers with rationales
,Table of Contents
Content Area Questions Key Topics
Hiv/aids Pathophysiology 1-25 Count, Receiving, Reports, Transplant, Important
Transmission AND
Prevention
Hiv/aids Clinical 26-50 Finding, Receiving, Chemotherapy, Prescribed, Laboratory
Manifestations Opportunistic
Infections AND Antiretroviral
Therapy
Systemic Lupus 51-75 Finding, Chemotherapy, Count, Prescribed, Lupus
Erythematosus SLE
Pathophysiology Clinical
Manifestations AND
Management
Organ Transplantation 76-100 Receiving, Finding, Chemotherapy, Count, Reports
Preoperative Evaluation
Donor Matching AND
Immunosuppressive Therapy
Organ Transplantation 101-125 Receiving, Reports, Count, Chemotherapy, Finding
Postoperative Complications
Rejection AND Infection
Prevention
Cancer Pathophysiology 126-147 Cancer, Receiving, Prescribed, Finding, Therapy
RISK Factors Screening AND
Diagnosis
TOTAL 147 All questions include answers and detailed rationales
,Section A - Hiv/aids Pathophysiology Transmission AND
Prevention
Q1.
A patient on antiretroviral therapy with a CD4 count of 180 cells/mm³ and a new positive
serum cryptococcal antigen is admitted. Which nursing action is the priority?
A. Administer fluconazole as prescribed and B. Withhold all antiretrovirals until antifungal
monitor for increased intracranial pressure. therapy is complete.
C. Place the patient in a negative-pressure D. Obtain a tuberculin skin test and begin
room with N95 respirator. isoniazid prophylaxis.
Correct: A - Administer fluconazole as prescribed and monitor for increased intracranial
pressure.
Rationale:Cryptococcal antigen positivity with CD4 <200 indicates cryptococcal meningitis
risk; prompt antifungal therapy and ICP monitoring are priority. Antiretrovirals are continued,
not withheld; airborne precautions are not indicated for cryptococcus; TB screening is not the
immediate priority.
Why the other answers are wrong:
B. Antiretrovirals should be continued to preserve immune function, not withheld.
C. Cryptococcus is not transmitted person-to-person; airborne isolation is not required.
D. TB screening is important but not the immediate priority over treating active cryptococcal
infection.
Reference: Centers for Disease Control and Prevention. (2024). Guidelines for the Prevention and
Treatment of Opportunistic Infections in Adults and Adolescents with HIV.
Q2.
A patient with systemic lupus erythematosus (SLE) reports new-onset pleuritic chest pain,
dyspnea, and a low-grade fever. Which finding best supports the nurse's suspicion of
serositis rather than infection?
A. Elevated C-reactive protein B. Leukocytosis with left shift
C. Presence of anti-dsDNA antibodies D. Positive blood cultures
Correct: C - Presence of anti-dsDNA antibodies
Rationale:Anti-dsDNA antibodies correlate with SLE disease activity and serositis, helping
differentiate lupus flare from infection. CRP and leukocytosis can occur in both; positive blood
cultures would confirm infection, not serositis.
Why the other answers are wrong:
A. CRP is nonspecific and can rise in both infection and inflammation.
Page 3
, Section A - Hiv/aids Pathophysiology Transmission AND Prevention
B. Leukocytosis with left shift suggests infection rather than lupus serositis.
D. Positive blood cultures would indicate infection, not autoimmune serositis.
Reference: Fauci, A.S., et al. (2024). Harrison's Principles of Internal Medicine, 22nd Ed., Ch. 349.
Q3.
A patient is 6 hours post-kidney transplant from a deceased donor. Which assessment
finding requires immediate notification of the transplant surgeon?
A. Urine output of 30 mL/hr with clear yellow B. Serum creatinine decreased from 6.2 to
urine 5.8 mg/dL
C. New-onset oliguria with a tender, swollen D. Pain at the incision site rated 4/10
graft site
Correct: C - New-onset oliguria with a tender, swollen graft site
Rationale:Oliguria with graft tenderness and swelling suggests acute rejection or vascular
thrombosis, requiring immediate intervention. The other findings are expected or improving
post-transplant.
Why the other answers are wrong:
A. Urine output of 30 mL/hr is acceptable and indicates graft function.
B. A falling creatinine indicates improving graft function.
D. Incisional pain is expected and manageable with analgesia.
Reference: Hinkle, J.L., & Cheever, K.H. (2022). Brunner & Suddarth's Textbook of Medical-Surgical
Nursing, 15th Ed., Ch. 54.
Q4.
Which instruction is most important for the nurse to include when teaching a patient
about safe handling of oral chemotherapy at home?
A. Store the medication in the bathroom for B. Crush tablets if swallowing is difficult.
convenience.
C. Wear gloves when handling the D. Double the dose if a dose is missed.
medication and wash hands after.
Correct: C - Wear gloves when handling the medication and wash hands after.
Rationale:Oral chemotherapy is hazardous; gloves and hand hygiene reduce exposure.
Bathroom storage risks moisture degradation; crushing may alter absorption or cause
aerosolization; doubling doses is unsafe.
Why the other answers are wrong:
A. Bathroom humidity can degrade the drug; a dry, secure location is preferred.
B. Crushing can aerosolize hazardous particles and alter pharmacokinetics.
D. Doubling a missed dose can cause severe toxicity.
Page 4
SLE, ORGAN TRANSPLANT, CANCER, CHEMOTHERAPY,
ONCOLOGY EMERGENCIES & DISASTER TRIAGE | GALEN
COLLEGE OF NURSING.
147 Questions with Answers and Detailed Rationales
100 PERCENT GUARANTEED PASS
INSTANT DOWNLOAD ANSWERS INCLUDED
IMPORTANCE OF THIS DOCUMENT
This comprehensive examination preparation guide has been meticulously developed to help you succeed in the
NUR 265 EXAM 4 STUDY GUIDE 2026 | UNITS 9-11 | HIV/AIDS, SLE, ORGAN TRANSPLANT, CANCER,
CHEMOTHERAPY, ONCOLOGY EMERGENCIES & DISASTER TRIAGE | GALEN COLLEGE OF NURSING.. It
contains 147 carefully selected questions that reflect the most current exam content and testing strategies. Each
question is accompanied by a correct answer and a detailed rationale that explains the underlying
pathophysiology, pharmacology, or clinical reasoning.
Self-Assessment – Test your knowledge and Exam Preparation – Familiarize yourself with the
identify areas requiring further question format and content
study areas
Concept Reinforcement – Deepen your Confidence Building – Develop test-taking
understanding through strategies and reduce
evidence-based exam anxiety
rationales
Time Management – Practice answering
questions under simulated
exam conditions
Review Summary 147 Questions
Foundations - Application - NUR 265 4 Study Guide 2026 Units 9 11 Hiv/aids SLE Organ Transplant
Cancer Chemotherapy Oncology Emergencies & Disaster Triage Galen College OF Nursing Nursing Complex
Health Alterations Hiv/aids SLE Organ Transplant Oncology Chemotherapy Oncologic Emergencies Disaster
Triage Undergraduate YEAR 3 BSN Galen College OF Nursing
All answers with rationales
,Table of Contents
Content Area Questions Key Topics
Hiv/aids Pathophysiology 1-25 Count, Receiving, Reports, Transplant, Important
Transmission AND
Prevention
Hiv/aids Clinical 26-50 Finding, Receiving, Chemotherapy, Prescribed, Laboratory
Manifestations Opportunistic
Infections AND Antiretroviral
Therapy
Systemic Lupus 51-75 Finding, Chemotherapy, Count, Prescribed, Lupus
Erythematosus SLE
Pathophysiology Clinical
Manifestations AND
Management
Organ Transplantation 76-100 Receiving, Finding, Chemotherapy, Count, Reports
Preoperative Evaluation
Donor Matching AND
Immunosuppressive Therapy
Organ Transplantation 101-125 Receiving, Reports, Count, Chemotherapy, Finding
Postoperative Complications
Rejection AND Infection
Prevention
Cancer Pathophysiology 126-147 Cancer, Receiving, Prescribed, Finding, Therapy
RISK Factors Screening AND
Diagnosis
TOTAL 147 All questions include answers and detailed rationales
,Section A - Hiv/aids Pathophysiology Transmission AND
Prevention
Q1.
A patient on antiretroviral therapy with a CD4 count of 180 cells/mm³ and a new positive
serum cryptococcal antigen is admitted. Which nursing action is the priority?
A. Administer fluconazole as prescribed and B. Withhold all antiretrovirals until antifungal
monitor for increased intracranial pressure. therapy is complete.
C. Place the patient in a negative-pressure D. Obtain a tuberculin skin test and begin
room with N95 respirator. isoniazid prophylaxis.
Correct: A - Administer fluconazole as prescribed and monitor for increased intracranial
pressure.
Rationale:Cryptococcal antigen positivity with CD4 <200 indicates cryptococcal meningitis
risk; prompt antifungal therapy and ICP monitoring are priority. Antiretrovirals are continued,
not withheld; airborne precautions are not indicated for cryptococcus; TB screening is not the
immediate priority.
Why the other answers are wrong:
B. Antiretrovirals should be continued to preserve immune function, not withheld.
C. Cryptococcus is not transmitted person-to-person; airborne isolation is not required.
D. TB screening is important but not the immediate priority over treating active cryptococcal
infection.
Reference: Centers for Disease Control and Prevention. (2024). Guidelines for the Prevention and
Treatment of Opportunistic Infections in Adults and Adolescents with HIV.
Q2.
A patient with systemic lupus erythematosus (SLE) reports new-onset pleuritic chest pain,
dyspnea, and a low-grade fever. Which finding best supports the nurse's suspicion of
serositis rather than infection?
A. Elevated C-reactive protein B. Leukocytosis with left shift
C. Presence of anti-dsDNA antibodies D. Positive blood cultures
Correct: C - Presence of anti-dsDNA antibodies
Rationale:Anti-dsDNA antibodies correlate with SLE disease activity and serositis, helping
differentiate lupus flare from infection. CRP and leukocytosis can occur in both; positive blood
cultures would confirm infection, not serositis.
Why the other answers are wrong:
A. CRP is nonspecific and can rise in both infection and inflammation.
Page 3
, Section A - Hiv/aids Pathophysiology Transmission AND Prevention
B. Leukocytosis with left shift suggests infection rather than lupus serositis.
D. Positive blood cultures would indicate infection, not autoimmune serositis.
Reference: Fauci, A.S., et al. (2024). Harrison's Principles of Internal Medicine, 22nd Ed., Ch. 349.
Q3.
A patient is 6 hours post-kidney transplant from a deceased donor. Which assessment
finding requires immediate notification of the transplant surgeon?
A. Urine output of 30 mL/hr with clear yellow B. Serum creatinine decreased from 6.2 to
urine 5.8 mg/dL
C. New-onset oliguria with a tender, swollen D. Pain at the incision site rated 4/10
graft site
Correct: C - New-onset oliguria with a tender, swollen graft site
Rationale:Oliguria with graft tenderness and swelling suggests acute rejection or vascular
thrombosis, requiring immediate intervention. The other findings are expected or improving
post-transplant.
Why the other answers are wrong:
A. Urine output of 30 mL/hr is acceptable and indicates graft function.
B. A falling creatinine indicates improving graft function.
D. Incisional pain is expected and manageable with analgesia.
Reference: Hinkle, J.L., & Cheever, K.H. (2022). Brunner & Suddarth's Textbook of Medical-Surgical
Nursing, 15th Ed., Ch. 54.
Q4.
Which instruction is most important for the nurse to include when teaching a patient
about safe handling of oral chemotherapy at home?
A. Store the medication in the bathroom for B. Crush tablets if swallowing is difficult.
convenience.
C. Wear gloves when handling the D. Double the dose if a dose is missed.
medication and wash hands after.
Correct: C - Wear gloves when handling the medication and wash hands after.
Rationale:Oral chemotherapy is hazardous; gloves and hand hygiene reduce exposure.
Bathroom storage risks moisture degradation; crushing may alter absorption or cause
aerosolization; doubling doses is unsafe.
Why the other answers are wrong:
A. Bathroom humidity can degrade the drug; a dry, secure location is preferred.
B. Crushing can aerosolize hazardous particles and alter pharmacokinetics.
D. Doubling a missed dose can cause severe toxicity.
Page 4
