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Advanced Pathophysiology Exam 1 | Study Guide, Practice Questions & Exam Review

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This Advanced Pathophysiology Exam 1 Study Guide provides focused review of foundational and advanced pathophysiology concepts, disease processes, cellular mechanisms, clinical concepts, and key principles relevant to the first exam. It is designed to support nursing and advanced healthcare students with studying, revision, practice questions, test preparation, and exam review.

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Advanced
Pathophysiology Exam 1 |
Study Guide, Practice
Questions & Exam
Review
|Guaranteed success|

,Incidence A measure of disease that allows us to determine a person's probability of
being diagnosed with a disease during a given period of time. Therefore,
incidence is the number of newly diagnosed cases of a disease. An incidence
rate is the number of new cases of a disease divided by the number of persons
at risk for the disease.
Conveys information about the risk of contracting the disease.


Ratio The quantitative relation between two amounts showing the number of times
one value contains or is contained within the other.


Primary Prevention Altering susceptibility or reducing exposure for susceptible persons
*Both illness and disease are absent


example: vaccinations, healthy lifestyles


Secondary Prevention Early detection, screening, and management of disease
*Illness absent, disease present


example: screenings and testings


Tertiary Prevention Rehabilitation, supportive care, reducing disability, and restoring effective
functioning
*Both illness and disease present


example: education


Epidemiology study of the patterns of disease involving populations; examining the
occurrence, incidence, prevalence, transmission, and distribution of diseases in
large groups of populations/people


Endemic A disease theat is native to a local region


Epidemic When a disease is disseninated to many individals at the same time
(spread to many people at the same time)


Pandemic Epidemics that affect large geographic regions, perhaps spreading worldwide.
(spread to large geographic areas)




Chapter 2: Homeostasis and Adaptive Responses to
Stressors


Homeostasis A state of being in which all systems are in balance around a articular ideal "set-
point"

, Exhausation Point where body can no longer return to homeostasis following a prolonged
exposure to noxious agents


Allostatic Overload "Cost" of body's organs and tissues for an excessive or ineffectively regulated
allostatic response; effect of "wear and tear" on the body


Adaptation Adaptation: biopsychosocial process of change in response to new or altered
circumstances, internal or external in origin
Coping: behavioral adaptive response to a stressor using culturally based
coping mechanisms
Adaptation and coping: terms used interchangeably


Arousal Includes alterations in responsiveness to homeostatic pressures, sensory stimuli
and emotional reactivity, and to changes in motor activity


Function of Cortisol Primary glucocorticoid
Affects protein metabolism
Promotes appetite and food-seeking behaviors
Has anti-inflammatory effects
Chemical mediator in the inflammation response of the body


Adrenal corticosteroid critical to maintenance of homeostasis
May synergize or antagonize effects of catecholamines


Chapter 3: Cell Structure and Function


Endocrine Communication Hormones traveling in the bloodstream
Long range signaling




Neurocrine Communication Neurons firing information through synapses
Signals travel a very small distance between neuron and target cell


Paracrine Communcation Signaling through the extraceullar fluid between cells in a tissue
Localized areas of communication


Autocrine Communcation Localized signaling in which the secreting cell is also the target cell
Feedback to self

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