RN Pharmacology ATI 2026 | Actual Proctored
Exam with NGN Questions, Latest Answers and
Comprehensive Exam Preparation
,
, Section 1: Pharmacokinetics & Pharmacodynamics (Q1–10)
Q1. A nurse is teaching a client about the "first-pass effect." Which route is most affected?
A. Intravenous
B. Sublingual
C. Oral
D. Transdermal
Answer: C
Rationale: Oral medications travel to the liver via the portal vein, where a large portion may be
metabolized before reaching systemic circulation, reducing bioavailability.
Q2. A nurse is reviewing a prescription for a "trough level." When should the blood be drawn?
A. 30 minutes after the dose
B. Mid-way between doses
C. 15 minutes before the next dose
D. 2 hours after infusion starts
Answer: C
Rationale: The trough represents the lowest drug concentration and is measured immediately
before the next scheduled dose.
Exam with NGN Questions, Latest Answers and
Comprehensive Exam Preparation
,
, Section 1: Pharmacokinetics & Pharmacodynamics (Q1–10)
Q1. A nurse is teaching a client about the "first-pass effect." Which route is most affected?
A. Intravenous
B. Sublingual
C. Oral
D. Transdermal
Answer: C
Rationale: Oral medications travel to the liver via the portal vein, where a large portion may be
metabolized before reaching systemic circulation, reducing bioavailability.
Q2. A nurse is reviewing a prescription for a "trough level." When should the blood be drawn?
A. 30 minutes after the dose
B. Mid-way between doses
C. 15 minutes before the next dose
D. 2 hours after infusion starts
Answer: C
Rationale: The trough represents the lowest drug concentration and is measured immediately
before the next scheduled dose.
