ATI PN PHARMACOLOGY 2026
PROCTORED EXAM COMPRISING NGN
AND ALL QUESTIONS AND CORRECT
ANSWERS (VERIFIED ANSWERS)
PLUS RATIONALES 2026 Q&A | LEVEL
3 PASS | INSTANT DOWNLOAD PDF
Core Domains
Pharmacokinetics, Pharmacodynamics, and Medication Principles
Safe Medication Administration, Dosage Calculation, and Error
Prevention
Cardiovascular and Hematologic Medications
Endocrine Medications (Insulin, Thyroid, Oral Hypoglycemics,
Corticosteroids)
Anti-Infective Agents (Antibiotics, Antivirals, Antifungals)
Neurologic, Psychiatric, and Pain Management Medications
Gastrointestinal, Respiratory, and Anti-Inflammatory Drugs
,Maternal/Child Pharmacology and Emergency Medications
NGN Clinical Judgment and Priority Nursing Interventions
Introduction
This proctored assessment evaluates practical nursing knowledge
in pharmacology across the lifespan. It assesses
pharmacokinetics, pharmacodynamics, safe medication
administration, dosage calculation, cardiovascular, endocrine,
anti-infective, neurologic, psychiatric, and pain management
pharmacology, gastrointestinal and respiratory medications,
maternal and child pharmacology, and emergency medications.
The Next Generation NCLEX and multiple-choice and scenario-
based structure emphasizes clinical judgment, prioritization, and
safe decision-making. Candidates must apply drug classifications,
adverse effects, monitoring parameters, and patient education to
provide competent, safe pharmacological nursing care.
Section One: Questions 1–100
1. A nurse is preparing to administer an otic medication to
a 6-month-old infant. Which of the following actions is
correct?
A. Pull the pinna up and back
B. Pull the earlobe straight out
C. Pull the pinna down and back
,D. Place the client in a supine position with the head turned away
from the affected ear
C. Pull the pinna down and back
RATIONALE: For children under 3 years of age, the pinna
should be pulled down and back to straighten the ear canal. For
adults and children over 3, the pinna is pulled up and back.
2. A client is prescribed colchicine for acute gout. Which of
the following instructions should the nurse include?
A. "Take this medication with a full glass of water."
B. "This medication is safe for clients with renal impairment."
C. "You may experience constipation as a common side effect."
D. "Take this medication at the first sign of a gout attack."
D. "Take this medication at the first sign of a gout attack."
RATIONALE: Colchicine is most effective when taken at the
first sign of a gout flare. It is not safe for renal impairment and
can cause diarrhea, not constipation.
3. A nurse is caring for a client who is receiving IV
acyclovir. Which of the following actions is most
important?
A. Monitor the IV site for infiltration
B. Encourage oral fluids
C. Monitor urine output
D. Administer the medication over 1 hour
C. Monitor urine output
RATIONALE: Acyclovir can crystallize in the renal tubules,
causing nephrotoxicity. Monitoring urine output is essential to
ensure adequate renal perfusion.
, 4. A client is prescribed cefuroxime. Which of the following
statements indicates the client understands the
medication?
A. "I can stop this medication if my symptoms improve."
B. "I should take this medication with food to reduce stomach
upset."
C. "I can drink alcohol while taking this medication."
D. "This medication is safe for my penicillin allergy."
B. "I should take this medication with food to reduce stomach
upset."
RATIONALE: Cefuroxime (a cephalosporin) can cause GI
upset; taking it with food helps reduce this. It should be taken for
the full course.
5. A nurse is reinforcing teaching with a client regarding
how to mix regular insulin and NPH insulin in the same
syringe. Which action, if performed by the client, indicates
the need for further teaching?
A. Withdraws the NPH insulin first
B. Withdraws the regular insulin first
C. Injects air into the NPH insulin vial first
D. Injects an amount of air equal to the desired dose of insulin
into the vial
A. Withdraws the NPH insulin first
RATIONALE: When preparing a mixture of regular insulin with
another insulin preparation, the regular insulin is drawn into the
syringe first. This sequence avoids contaminating the vial of
regular insulin.
PROCTORED EXAM COMPRISING NGN
AND ALL QUESTIONS AND CORRECT
ANSWERS (VERIFIED ANSWERS)
PLUS RATIONALES 2026 Q&A | LEVEL
3 PASS | INSTANT DOWNLOAD PDF
Core Domains
Pharmacokinetics, Pharmacodynamics, and Medication Principles
Safe Medication Administration, Dosage Calculation, and Error
Prevention
Cardiovascular and Hematologic Medications
Endocrine Medications (Insulin, Thyroid, Oral Hypoglycemics,
Corticosteroids)
Anti-Infective Agents (Antibiotics, Antivirals, Antifungals)
Neurologic, Psychiatric, and Pain Management Medications
Gastrointestinal, Respiratory, and Anti-Inflammatory Drugs
,Maternal/Child Pharmacology and Emergency Medications
NGN Clinical Judgment and Priority Nursing Interventions
Introduction
This proctored assessment evaluates practical nursing knowledge
in pharmacology across the lifespan. It assesses
pharmacokinetics, pharmacodynamics, safe medication
administration, dosage calculation, cardiovascular, endocrine,
anti-infective, neurologic, psychiatric, and pain management
pharmacology, gastrointestinal and respiratory medications,
maternal and child pharmacology, and emergency medications.
The Next Generation NCLEX and multiple-choice and scenario-
based structure emphasizes clinical judgment, prioritization, and
safe decision-making. Candidates must apply drug classifications,
adverse effects, monitoring parameters, and patient education to
provide competent, safe pharmacological nursing care.
Section One: Questions 1–100
1. A nurse is preparing to administer an otic medication to
a 6-month-old infant. Which of the following actions is
correct?
A. Pull the pinna up and back
B. Pull the earlobe straight out
C. Pull the pinna down and back
,D. Place the client in a supine position with the head turned away
from the affected ear
C. Pull the pinna down and back
RATIONALE: For children under 3 years of age, the pinna
should be pulled down and back to straighten the ear canal. For
adults and children over 3, the pinna is pulled up and back.
2. A client is prescribed colchicine for acute gout. Which of
the following instructions should the nurse include?
A. "Take this medication with a full glass of water."
B. "This medication is safe for clients with renal impairment."
C. "You may experience constipation as a common side effect."
D. "Take this medication at the first sign of a gout attack."
D. "Take this medication at the first sign of a gout attack."
RATIONALE: Colchicine is most effective when taken at the
first sign of a gout flare. It is not safe for renal impairment and
can cause diarrhea, not constipation.
3. A nurse is caring for a client who is receiving IV
acyclovir. Which of the following actions is most
important?
A. Monitor the IV site for infiltration
B. Encourage oral fluids
C. Monitor urine output
D. Administer the medication over 1 hour
C. Monitor urine output
RATIONALE: Acyclovir can crystallize in the renal tubules,
causing nephrotoxicity. Monitoring urine output is essential to
ensure adequate renal perfusion.
, 4. A client is prescribed cefuroxime. Which of the following
statements indicates the client understands the
medication?
A. "I can stop this medication if my symptoms improve."
B. "I should take this medication with food to reduce stomach
upset."
C. "I can drink alcohol while taking this medication."
D. "This medication is safe for my penicillin allergy."
B. "I should take this medication with food to reduce stomach
upset."
RATIONALE: Cefuroxime (a cephalosporin) can cause GI
upset; taking it with food helps reduce this. It should be taken for
the full course.
5. A nurse is reinforcing teaching with a client regarding
how to mix regular insulin and NPH insulin in the same
syringe. Which action, if performed by the client, indicates
the need for further teaching?
A. Withdraws the NPH insulin first
B. Withdraws the regular insulin first
C. Injects air into the NPH insulin vial first
D. Injects an amount of air equal to the desired dose of insulin
into the vial
A. Withdraws the NPH insulin first
RATIONALE: When preparing a mixture of regular insulin with
another insulin preparation, the regular insulin is drawn into the
syringe first. This sequence avoids contaminating the vial of
regular insulin.
