20 QUESTIONS · ANSWER KEY
Pharmacology Principles and Drug Response
75 min · Pass mark 75%
Drug Action and Receptors 18 MIN
1 MULTIPLE CHOICE
A substance binds to a receptor and activates it, producing a response similar to that of the body's natural
chemical. Which term best describes the substance?
A Side effect
B Receptor
C Antagonist
D Agonist
ANSWER D
WHY An agonist binds to and activates a receptor. An antagonist blocks or reduces receptor activation, while a receptor is the protein the
drug binds to.
2 TRUE / FALSE
Pharmacodynamics examines how the body absorbs, distributes, metabolizes, and excretes a drug over time.
ANSWER False
WHY Those processes are pharmacokinetics. Pharmacodynamics concerns how a drug produces effects and how concentration relates to
response.
3 SHORT ANSWER
A drug binds to a receptor but reduces the effect of an agonist. Identify the drug's receptor-level role and explain
the defining action.
MODEL ANSWER
It is an antagonist because it binds to the receptor and blocks or reduces the effect of an agonist.
WHY An antagonist binds to a receptor without activating it as an agonist does, thereby blocking or reducing an agonist's effect.
1/6
, 4 MATCHING
Match each pharmacology term to the definition that best distinguishes it.
CORRECT PAIRS
Pharmacokinetics → How the body absorbs, distributes, metabolizes, and excretes a drug over time
Pharmacodynamics → How a drug produces effects on the body, including concentration and response
Receptor → A specific protein on or inside a cell that a drug can bind to
WHY Pharmacokinetics describes the body's handling of drugs, pharmacodynamics describes drug effects, and receptors are the binding
proteins involved in biological responses.
5 FILL IN THE BLANK
Complete the statements with the most precise terms.
A drug that activates a receptor is an agonist. A drug that binds and reduces an agonist's effect is an antagonist.
ANSWERS
1 agonist
2 antagonist
WHY An agonist activates a receptor, whereas an antagonist binds to a receptor and blocks or reduces the effect of an agonist or natural
chemical.
Drug Handling and Administration 19 MIN
6 MULTIPLE CHOICE
Which measure specifically describes the fraction of an administered drug that reaches systemic circulation
unchanged?
A Bioavailability
B Dosage
C Therapeutic index
D Tolerance
ANSWER A
WHY Bioavailability is the fraction of a drug that reaches systemic circulation unchanged. Dosage is the amount administered, therapeutic
index compares toxic and effective doses, and tolerance is a decreased response over time.
2/6
Pharmacology Principles and Drug Response
75 min · Pass mark 75%
Drug Action and Receptors 18 MIN
1 MULTIPLE CHOICE
A substance binds to a receptor and activates it, producing a response similar to that of the body's natural
chemical. Which term best describes the substance?
A Side effect
B Receptor
C Antagonist
D Agonist
ANSWER D
WHY An agonist binds to and activates a receptor. An antagonist blocks or reduces receptor activation, while a receptor is the protein the
drug binds to.
2 TRUE / FALSE
Pharmacodynamics examines how the body absorbs, distributes, metabolizes, and excretes a drug over time.
ANSWER False
WHY Those processes are pharmacokinetics. Pharmacodynamics concerns how a drug produces effects and how concentration relates to
response.
3 SHORT ANSWER
A drug binds to a receptor but reduces the effect of an agonist. Identify the drug's receptor-level role and explain
the defining action.
MODEL ANSWER
It is an antagonist because it binds to the receptor and blocks or reduces the effect of an agonist.
WHY An antagonist binds to a receptor without activating it as an agonist does, thereby blocking or reducing an agonist's effect.
1/6
, 4 MATCHING
Match each pharmacology term to the definition that best distinguishes it.
CORRECT PAIRS
Pharmacokinetics → How the body absorbs, distributes, metabolizes, and excretes a drug over time
Pharmacodynamics → How a drug produces effects on the body, including concentration and response
Receptor → A specific protein on or inside a cell that a drug can bind to
WHY Pharmacokinetics describes the body's handling of drugs, pharmacodynamics describes drug effects, and receptors are the binding
proteins involved in biological responses.
5 FILL IN THE BLANK
Complete the statements with the most precise terms.
A drug that activates a receptor is an agonist. A drug that binds and reduces an agonist's effect is an antagonist.
ANSWERS
1 agonist
2 antagonist
WHY An agonist activates a receptor, whereas an antagonist binds to a receptor and blocks or reduces the effect of an agonist or natural
chemical.
Drug Handling and Administration 19 MIN
6 MULTIPLE CHOICE
Which measure specifically describes the fraction of an administered drug that reaches systemic circulation
unchanged?
A Bioavailability
B Dosage
C Therapeutic index
D Tolerance
ANSWER A
WHY Bioavailability is the fraction of a drug that reaches systemic circulation unchanged. Dosage is the amount administered, therapeutic
index compares toxic and effective doses, and tolerance is a decreased response over time.
2/6
