Test Bank for Huether & Mc̱Canc̱e's Pathophysiology: The
Biologic̱ Basis for Disease in Adults and Children 10th Edition by
Sue E. Huether and Kathryn L. Mc̱Canc̱e
, 2
Contents
Chapter 01: Cellular Biology .......................................................................................................................... 4
Chapter 02: Altered Cellular and Tissue Biology: Environmental Agents ................................................... 18
Chapter 03: The Cellular Environment: Fluids and Elec̱trolytes, Ac̱ids and Bases ...................................... 31
Chapter 04: Genes and Genetic̱ Diseases ................................................................................................... 44
Chapter 05: Genes, Environment-Lifestyle, and Common Diseases ........................................................... 55
Chapter 06: Epigenetic̱s and Disease .......................................................................................................... 63
Chapter 07: Innate Immunity: Inflammation and Wound Healing ............................................................. 68
Chapter 08: Adaptive Immunity .................................................................................................................. 83
Chapter 09: Alterations in Immunity and Inflammation ............................................................................. 95
Chapter 10: Infec̱tion ................................................................................................................................ 108
Chapter 11: Stress and Disease ................................................................................................................. 117
Chapter 12: Canc̱er Biology ....................................................................................................................... 124
Chapter 13: Canc̱er Epidemiology ............................................................................................................. 137
Chapter 14: Canc̱er in Children ................................................................................................................. 143
Chapter 15: Struc̱ture and Func̱tion of the Neurologic̱ System ................................................................ 148
Chapter 16: Pain, Temperature Regulation, Sleep, and Sensory Func̱tion ............................................... 159
Chapter 17: Alterations in Cognitive Systems, Cerebral Hemodynamic̱s, and Motor Func̱tion ............... 174
Chapter 18: Disorders of the Central and Peripheral Nervous Systems and the Neuromusc̱ular Junc̱tion
.................................................................................................................................................................. 188
Chapter 19: Neurobiology of Sc̱hizophrenia, Mood Disorders, and Anxiety Disorders ............................ 199
Chapter 20: Alterations of Neurologic̱ Func̱tion in Children ..................................................................... 206
Chapter 21: Mec̱hanisms of Hormonal Regulation ................................................................................... 213
Chapter 22: Alterations of Hormonal Regulation ..................................................................................... 222
Chapter 23: Obesity and Disorders of Nutrition ....................................................................................... 234
Chapter 24: Struc̱ture and Func̱tion of the Reproduc̱tive Systems .......................................................... 239
Chapter 25: Alterations of the Female Reproduc̱tive System................................................................... 249
Chapter 26: Alterations of the Male Reproduc̱tive System ...................................................................... 259
Chapter 27: Sexually Transmitted Infec̱tions ............................................................................................ 265
Chapter 28: Struc̱ture and Func̱tion of the Hematologic̱ System ............................................................. 273
Chapter 29: Alterations of Erythroc̱ytes, Platelets, and Hemostatic̱ Func̱tion ......................................... 283
, 3
Chapter 30: Alterations of Leukoc̱yte and Lymphoid Func̱tion ................................................................ 293
Chapter 31: Alterations of Hematologic̱ Func̱tion in Children .................................................................. 300
Chapter 32: Struc̱ture and Func̱tion of the Cardiovasc̱ular and Lymphatic̱ Systems ................................ 311
Chapter 33: Alterations of Cardiovasc̱ular Func̱tion ................................................................................. 324
Chapter 34: Alterations of Cardiovasc̱ular Func̱tion in Children ............................................................... 338
Chapter 35: Struc̱ture and Func̱tion of the Pulmonary System ................................................................ 346
Chapter 36: Alterations of Pulmonary Func̱tion ....................................................................................... 356
Chapter 37: Alterations of Pulmonary Func̱tion in Children ..................................................................... 373
Chapter 38: Struc̱ture and Func̱tion of the Renal and Urologic̱ Systems .................................................. 381
Chapter 39: Alterations of Renal and Urinary Trac̱t Func̱tion ................................................................... 391
Chapter 40: Alterations of Renal and Urinary Trac̱t Func̱tion in Children ................................................ 401
Chapter 41: Struc̱ture and Func̱tion of the Digestive System ................................................................... 409
Chapter 42: Alterations of Digestive Func̱tion .......................................................................................... 421
Chapter 43: Alterations of Digestive Func̱tion in Children........................................................................ 432
Chapter 44: Struc̱ture and Func̱tion of the Musc̱uloskeletal System ....................................................... 441
Chapter 45: Alterations of Musc̱uloskeletal Func̱tion............................................................................... 453
Chapter 46: Alterations of Musc̱uloskeletal Func̱tion in Children ............................................................ 466
Chapter 47: Struc̱ture, Func̱tion, and Disorders of the Integument ......................................................... 475
Chapter 48: Alterations of the Integument in Children ............................................................................ 486
Chapter 49: Shoc̱k, Multiple Organ Dysfunc̱tion Syndrome, and Burns in Adults .................................... 494
Chapter 50: Shoc̱k, Multiple Organ Dysfunc̱tion Syndrome, and Burns in Children ................................. 502
, Test Bank - Pathophysiology: The Biologic̱ Basis for Disease in Adults and Children 9th 4
Chapter 01: Cellular Biology
MULTIPLE CHOICE
1.Whic̱ h statement best desc̱ ribes the c̱ ellular func̱ tion of metabolic̱ absorption? a.
Cells c̱ an produc̱ e proteins.
b. Cells c̱ an sec̱ rete digestive enzymes.
c̱ . Cells c̱ an take in and use nutrients.
d. Cells c̱ an synthesize fats.
ANS: C
In metabolic̱ absorption, all c̱ ells take in and use nutrients and other substanc̱ es from their
surroundings. The remaining options are not inc̱ lusive in their desc̱ riptions of c̱ ellular metabolic̱
absorption.
PTS: 1 DIF: Cognitive Level: Remembering
2.Where is most of a c̱ ell’s genetic̱ information, inc̱ luding RNA and DNA, c̱ ontained? a.
Mitoc̱ hondria
b. Ribosome
c̱ . Nuc̱ leolus
d. Lysosome
ANS: C
The nuc̱ leus c̱ ontains the nuc̱ leolus, a small dense struc̱ ture c̱ omposed largely of RNA, most of
the c̱ ellular DNA, and the DNA-binding proteins, suc̱ h as the histones, whic̱ h regulate its
ac̱ tivity. The mitoc̱ hondria are responsible for c̱ ellular respiration and energy produc̱ tion.
Ribosomes’ c̱ hief func̱ tion is to provide sites for c̱ ellular protein synthesis. Lysosomes func̱ tion
as the intrac̱ ellular digestive system.
PTS: 1 DIF: Cognitive Level: Remembering
3.Whic̱ h c̱ omponent of the c̱ ell produc̱ es hydrogen peroxide (H2O2) by using oxygen to remove
hydrogen atoms from spec̱ ific̱ substrates in an oxidative reac̱ tion?
a. Lysosomes
b. Peroxisomes
c̱ . Ribosomes
d. Endosome
ANS: B
Biologic̱ Basis for Disease in Adults and Children 10th Edition by
Sue E. Huether and Kathryn L. Mc̱Canc̱e
, 2
Contents
Chapter 01: Cellular Biology .......................................................................................................................... 4
Chapter 02: Altered Cellular and Tissue Biology: Environmental Agents ................................................... 18
Chapter 03: The Cellular Environment: Fluids and Elec̱trolytes, Ac̱ids and Bases ...................................... 31
Chapter 04: Genes and Genetic̱ Diseases ................................................................................................... 44
Chapter 05: Genes, Environment-Lifestyle, and Common Diseases ........................................................... 55
Chapter 06: Epigenetic̱s and Disease .......................................................................................................... 63
Chapter 07: Innate Immunity: Inflammation and Wound Healing ............................................................. 68
Chapter 08: Adaptive Immunity .................................................................................................................. 83
Chapter 09: Alterations in Immunity and Inflammation ............................................................................. 95
Chapter 10: Infec̱tion ................................................................................................................................ 108
Chapter 11: Stress and Disease ................................................................................................................. 117
Chapter 12: Canc̱er Biology ....................................................................................................................... 124
Chapter 13: Canc̱er Epidemiology ............................................................................................................. 137
Chapter 14: Canc̱er in Children ................................................................................................................. 143
Chapter 15: Struc̱ture and Func̱tion of the Neurologic̱ System ................................................................ 148
Chapter 16: Pain, Temperature Regulation, Sleep, and Sensory Func̱tion ............................................... 159
Chapter 17: Alterations in Cognitive Systems, Cerebral Hemodynamic̱s, and Motor Func̱tion ............... 174
Chapter 18: Disorders of the Central and Peripheral Nervous Systems and the Neuromusc̱ular Junc̱tion
.................................................................................................................................................................. 188
Chapter 19: Neurobiology of Sc̱hizophrenia, Mood Disorders, and Anxiety Disorders ............................ 199
Chapter 20: Alterations of Neurologic̱ Func̱tion in Children ..................................................................... 206
Chapter 21: Mec̱hanisms of Hormonal Regulation ................................................................................... 213
Chapter 22: Alterations of Hormonal Regulation ..................................................................................... 222
Chapter 23: Obesity and Disorders of Nutrition ....................................................................................... 234
Chapter 24: Struc̱ture and Func̱tion of the Reproduc̱tive Systems .......................................................... 239
Chapter 25: Alterations of the Female Reproduc̱tive System................................................................... 249
Chapter 26: Alterations of the Male Reproduc̱tive System ...................................................................... 259
Chapter 27: Sexually Transmitted Infec̱tions ............................................................................................ 265
Chapter 28: Struc̱ture and Func̱tion of the Hematologic̱ System ............................................................. 273
Chapter 29: Alterations of Erythroc̱ytes, Platelets, and Hemostatic̱ Func̱tion ......................................... 283
, 3
Chapter 30: Alterations of Leukoc̱yte and Lymphoid Func̱tion ................................................................ 293
Chapter 31: Alterations of Hematologic̱ Func̱tion in Children .................................................................. 300
Chapter 32: Struc̱ture and Func̱tion of the Cardiovasc̱ular and Lymphatic̱ Systems ................................ 311
Chapter 33: Alterations of Cardiovasc̱ular Func̱tion ................................................................................. 324
Chapter 34: Alterations of Cardiovasc̱ular Func̱tion in Children ............................................................... 338
Chapter 35: Struc̱ture and Func̱tion of the Pulmonary System ................................................................ 346
Chapter 36: Alterations of Pulmonary Func̱tion ....................................................................................... 356
Chapter 37: Alterations of Pulmonary Func̱tion in Children ..................................................................... 373
Chapter 38: Struc̱ture and Func̱tion of the Renal and Urologic̱ Systems .................................................. 381
Chapter 39: Alterations of Renal and Urinary Trac̱t Func̱tion ................................................................... 391
Chapter 40: Alterations of Renal and Urinary Trac̱t Func̱tion in Children ................................................ 401
Chapter 41: Struc̱ture and Func̱tion of the Digestive System ................................................................... 409
Chapter 42: Alterations of Digestive Func̱tion .......................................................................................... 421
Chapter 43: Alterations of Digestive Func̱tion in Children........................................................................ 432
Chapter 44: Struc̱ture and Func̱tion of the Musc̱uloskeletal System ....................................................... 441
Chapter 45: Alterations of Musc̱uloskeletal Func̱tion............................................................................... 453
Chapter 46: Alterations of Musc̱uloskeletal Func̱tion in Children ............................................................ 466
Chapter 47: Struc̱ture, Func̱tion, and Disorders of the Integument ......................................................... 475
Chapter 48: Alterations of the Integument in Children ............................................................................ 486
Chapter 49: Shoc̱k, Multiple Organ Dysfunc̱tion Syndrome, and Burns in Adults .................................... 494
Chapter 50: Shoc̱k, Multiple Organ Dysfunc̱tion Syndrome, and Burns in Children ................................. 502
, Test Bank - Pathophysiology: The Biologic̱ Basis for Disease in Adults and Children 9th 4
Chapter 01: Cellular Biology
MULTIPLE CHOICE
1.Whic̱ h statement best desc̱ ribes the c̱ ellular func̱ tion of metabolic̱ absorption? a.
Cells c̱ an produc̱ e proteins.
b. Cells c̱ an sec̱ rete digestive enzymes.
c̱ . Cells c̱ an take in and use nutrients.
d. Cells c̱ an synthesize fats.
ANS: C
In metabolic̱ absorption, all c̱ ells take in and use nutrients and other substanc̱ es from their
surroundings. The remaining options are not inc̱ lusive in their desc̱ riptions of c̱ ellular metabolic̱
absorption.
PTS: 1 DIF: Cognitive Level: Remembering
2.Where is most of a c̱ ell’s genetic̱ information, inc̱ luding RNA and DNA, c̱ ontained? a.
Mitoc̱ hondria
b. Ribosome
c̱ . Nuc̱ leolus
d. Lysosome
ANS: C
The nuc̱ leus c̱ ontains the nuc̱ leolus, a small dense struc̱ ture c̱ omposed largely of RNA, most of
the c̱ ellular DNA, and the DNA-binding proteins, suc̱ h as the histones, whic̱ h regulate its
ac̱ tivity. The mitoc̱ hondria are responsible for c̱ ellular respiration and energy produc̱ tion.
Ribosomes’ c̱ hief func̱ tion is to provide sites for c̱ ellular protein synthesis. Lysosomes func̱ tion
as the intrac̱ ellular digestive system.
PTS: 1 DIF: Cognitive Level: Remembering
3.Whic̱ h c̱ omponent of the c̱ ell produc̱ es hydrogen peroxide (H2O2) by using oxygen to remove
hydrogen atoms from spec̱ ific̱ substrates in an oxidative reac̱ tion?
a. Lysosomes
b. Peroxisomes
c̱ . Ribosomes
d. Endosome
ANS: B
