NUCLEAR MEDICINE TECHNOLOGY EXAM STUDY GUIDE WITH
VERIFIED QUESTIONS CORRECT ANSWERS | 2026/2027 LATEST
UPDATE | ALREADY GRADED A+
How does 201Tl decay? -
ANSWER
Electron capture with gamma emissions of 0.135 MeV and 0.167 MeV
What is the role of the standouts ion in the preparation of pharmaceuticals labeled with 99mTc? -
ANSWER
Stannous Chloride is a reducing agent which changes of valence state of Tc in pertechnetate. It has
no effect on either the amount of Al3+ or the radiation dose.
If an assay of a vial containing 131I shows 50 mCi present on May 2, approximately what will the
assay show on May 18? -
ANSWER
12.5 mCi
If a bone scan has been ordered on a 5-year-old girl, and the physician prescribes 62% of the adult
dose to be
given, how many mCi should be administered? -
ANSWER
12.4 mCi
If the biological half-life of an isotope is 6 h and the physical half-life is 12 h, what is the effective half-
life? -
ANSWER
4 hrs
Which of the following is used to abbreviate physical half life? -
ANSWER
Tp
,The physical half life of a radionuclide is the time it takes: -
ANSWER
for the nuclide to decay to one half of the original activity
If a kit has 310 mCi of activity present at 8:00 a.m., what will the vial assay show in 4 h and 10 min if
the decay factor is 0.618? -
ANSWER
192 mCi
A vial containing 99mTc is assayed at 9 am and contains 255 mCi. To calculate the remaining activity
at 3 pm what decay factor would be used? -
ANSWER
0.5
A vial of technetium eluate contains 50 mCi/ml. If 4 ml is
withdrawn and added to a diphosphonate kit containing
16 ml of solution, what volume would then need to be
withdrawn to prepare a 20 mCi dose at that moment? -
ANSWER
2
If a preparation of 99mTc mertiatide has 60 mCi of activity present at 8:30 am, how many mCi will be
present at 9 am? (Decay constant = 0.944) -
ANSWER
56.6
Which of the following is boiled during preparation? -
ANSWER
sulfur colloid
The presence of 12 ug Al+3 in 1 ml of 99mTc eluate is -
ANSWER
,Chemical impurity; Al 3+ ions from the alumina column of the must be less than 10 ug Al3+/ml of
eluate - this limit is set by US Pharmacopoeia
Which body decides on the acceptable levels of radionuclidic impurity? -
ANSWER
NRC & USP
Which of the following is an example of radionuclidic impurity:
1) presence of free 99mTc in a preparation of 99mTc sulfur colloid
2) Presence of 99Mo in 99mTc eluate
3) presence of aluminum ions in 99mTc eluate
4) presence of pyrogens in eluate -
ANSWER
2
What is the maximum amount of aluminum ions (AL3+) allowed in one milliliter of 99mTc eluate
according to the USP? -
ANSWER
10 μg
What is indicated by the front of an ITLC strip? -
ANSWER
This depends on the solvent and strip used
If a kit contains 140 mCi of 99mTc in 23 ml, how much volume must be withdrawn to obtain a dose of
5 mCi? -
ANSWER
0.8 mL - specific concentration is 140 mCi/23 ml or 6.1 mCi/ml
If a kit contains 140 mCi of 99mTc in 23 ml at 9:00 a.m., how much volume must be withdrawn to
obtain a dose of 5 mCi at 3:00 p.m.? -
ANSWER
1.6 ml
, An MAA kit contains 40 mCi of 99mTc in 5 ml at 8 am. What would be the best volume to be
withdrawn at 10 am if a perfusion lung scan is planned (decay constant = 0.794) -
ANSWER
0.63 ml
What is the most likely size of an MAA particle if correctly prepared? -
ANSWER
10-30 µm
99mTc MAA has a biological half life of 2-4 hrs; what will the effective half life be? -
ANSWER
1.5 - 2.4 hrs
Which radiopharmaceutical is made with 99mTc without a reducing agent? -
ANSWER
sulfur colloid
Which of the following is an example of radiochemical impurity?
1) presence of free 99mTc in a prep of 99mTc sulfur colloid
2) presence of 99Mo in 99mTc eluate
3) presence of aluminum ions in 99mTc eluate
4) presence of pyrogens in eluate -
ANSWER
1) presence of free 99mTc in prep of 99mTc sulfur colloid
Which of the following can be said regarding effective half-life? 1) It is always longer than the physical
half life 2) It always shorter than both the physical and biological half life 3) It is always shorter than
physical half life but longer than biological half life 4)It is always longer than the biological but
shorter than the physical half life? -
ANSWER
2
VERIFIED QUESTIONS CORRECT ANSWERS | 2026/2027 LATEST
UPDATE | ALREADY GRADED A+
How does 201Tl decay? -
ANSWER
Electron capture with gamma emissions of 0.135 MeV and 0.167 MeV
What is the role of the standouts ion in the preparation of pharmaceuticals labeled with 99mTc? -
ANSWER
Stannous Chloride is a reducing agent which changes of valence state of Tc in pertechnetate. It has
no effect on either the amount of Al3+ or the radiation dose.
If an assay of a vial containing 131I shows 50 mCi present on May 2, approximately what will the
assay show on May 18? -
ANSWER
12.5 mCi
If a bone scan has been ordered on a 5-year-old girl, and the physician prescribes 62% of the adult
dose to be
given, how many mCi should be administered? -
ANSWER
12.4 mCi
If the biological half-life of an isotope is 6 h and the physical half-life is 12 h, what is the effective half-
life? -
ANSWER
4 hrs
Which of the following is used to abbreviate physical half life? -
ANSWER
Tp
,The physical half life of a radionuclide is the time it takes: -
ANSWER
for the nuclide to decay to one half of the original activity
If a kit has 310 mCi of activity present at 8:00 a.m., what will the vial assay show in 4 h and 10 min if
the decay factor is 0.618? -
ANSWER
192 mCi
A vial containing 99mTc is assayed at 9 am and contains 255 mCi. To calculate the remaining activity
at 3 pm what decay factor would be used? -
ANSWER
0.5
A vial of technetium eluate contains 50 mCi/ml. If 4 ml is
withdrawn and added to a diphosphonate kit containing
16 ml of solution, what volume would then need to be
withdrawn to prepare a 20 mCi dose at that moment? -
ANSWER
2
If a preparation of 99mTc mertiatide has 60 mCi of activity present at 8:30 am, how many mCi will be
present at 9 am? (Decay constant = 0.944) -
ANSWER
56.6
Which of the following is boiled during preparation? -
ANSWER
sulfur colloid
The presence of 12 ug Al+3 in 1 ml of 99mTc eluate is -
ANSWER
,Chemical impurity; Al 3+ ions from the alumina column of the must be less than 10 ug Al3+/ml of
eluate - this limit is set by US Pharmacopoeia
Which body decides on the acceptable levels of radionuclidic impurity? -
ANSWER
NRC & USP
Which of the following is an example of radionuclidic impurity:
1) presence of free 99mTc in a preparation of 99mTc sulfur colloid
2) Presence of 99Mo in 99mTc eluate
3) presence of aluminum ions in 99mTc eluate
4) presence of pyrogens in eluate -
ANSWER
2
What is the maximum amount of aluminum ions (AL3+) allowed in one milliliter of 99mTc eluate
according to the USP? -
ANSWER
10 μg
What is indicated by the front of an ITLC strip? -
ANSWER
This depends on the solvent and strip used
If a kit contains 140 mCi of 99mTc in 23 ml, how much volume must be withdrawn to obtain a dose of
5 mCi? -
ANSWER
0.8 mL - specific concentration is 140 mCi/23 ml or 6.1 mCi/ml
If a kit contains 140 mCi of 99mTc in 23 ml at 9:00 a.m., how much volume must be withdrawn to
obtain a dose of 5 mCi at 3:00 p.m.? -
ANSWER
1.6 ml
, An MAA kit contains 40 mCi of 99mTc in 5 ml at 8 am. What would be the best volume to be
withdrawn at 10 am if a perfusion lung scan is planned (decay constant = 0.794) -
ANSWER
0.63 ml
What is the most likely size of an MAA particle if correctly prepared? -
ANSWER
10-30 µm
99mTc MAA has a biological half life of 2-4 hrs; what will the effective half life be? -
ANSWER
1.5 - 2.4 hrs
Which radiopharmaceutical is made with 99mTc without a reducing agent? -
ANSWER
sulfur colloid
Which of the following is an example of radiochemical impurity?
1) presence of free 99mTc in a prep of 99mTc sulfur colloid
2) presence of 99Mo in 99mTc eluate
3) presence of aluminum ions in 99mTc eluate
4) presence of pyrogens in eluate -
ANSWER
1) presence of free 99mTc in prep of 99mTc sulfur colloid
Which of the following can be said regarding effective half-life? 1) It is always longer than the physical
half life 2) It always shorter than both the physical and biological half life 3) It is always shorter than
physical half life but longer than biological half life 4)It is always longer than the biological but
shorter than the physical half life? -
ANSWER
2
