NCLEX-RN 2026 Questions
NCLEX-RN 2026 Questions with Correct
Answers Questions And Answers Practice
Questions with Solutions Newest | Already
Graded A+
A clinic nurse prepares a teaching plan for a client receiving an
antineoplastic medication. When implementing the plan, the nurse
should make which statement to the client?
A. "You can take aspirin as needed for headache."
B. "You can drink beverages containing alcohol in moderate amounts
each evening."
C. "You need to consult with the primary health care provider (PHCP)
before receiving immunizations."
D. "It is fine to receive a flu vaccine at the local health fair without PHCP
approval because the flu is so contagious."
C
Rationale:
Because antineoplastic medications lower the resistance of the body,
clients must be informed not to receive immunizations without the
PHCP's approval. Clients also need to avoid contact with individuals who
have recently received a live virus vaccine. Clients need to avoid aspirin
and aspirin-containing products to minimize the risk of bleeding, and
they need to avoid alcohol to minimize the risk of toxicity and
side/adverse effects.
The nurse is analyzing the laboratory results of a client with leukemia
who has received a regimen of chemotherapy. Which laboratory value
Page 1 of 96
, NCLEX-RN 2026 Questions
would the nurse specifically note as a result of the massive cell
destruction that occurred from the chemotherapy?
A. Anemia
B. Decreased platelets
C. Increased uric acid level
D. Decreased leukocyte count
C
Rationale:
Hyperuricemia is especially common following treatment for leukemias
and lymphomas, because chemotherapy results in massive cell kill.
Although options 1, 2, and 4 also may be noted, an increased uric acid
level is related specifically to cell destruction.
A client is brought to the emergency department in an unresponsive
state, and a diagnosis of hyperosmolar hyperglycemic syndrome is
made. The nurse would immediately prepare to initiate which
anticipated primary health care provider's prescription?
A. Endotracheal intubation
B. 100 units of NPH insulin
C. Intravenous infusion of normal saline
D. Intravenous infusion of sodium bicarbonate
C
Rationale:
The primary goal of treatment in hyperosmolar hyperglycemic
syndrome (HHS) is to rehydrate the client to restore fluid volume and to
correct electrolyte deficiency. Intravenous (IV) fluid replacement is
Page 2 of 96
, NCLEX-RN 2026 Questions
similar to that administered in diabetic ketoacidosis (DKA) and begins
with IV infusion of normal saline. Regular insulin, not NPH insulin,
would be administered. The use of sodium bicarbonate to correct
acidosis is avoided because it can precipitate a further drop in serum
potassium levels. Intubation and mechanical ventilation are not
required to treat HHS.
An external insulin pump is prescribed for a client with diabetes
mellitus. When the client asks the nurse about the functioning of the
pump, the nurse bases the response on which information about the
pump?
A. It is timed to release programmed doses of either short-duration or
NPH insulin into the bloodstream at specific intervals.
B. It continuously infuses small amounts of NPH insulin into the
bloodstream while regularly monitoring blood glucose levels.
C. It is surgically attached to the pancreas and infuses regular insulin
into the pancreas. This releases insulin into the bloodstream. D. It
administers a small continuous dose of short-duration insulin
subcutaneously. The client can self-administer an additional bolus dose
from the pump before each meal.
D
Rationale:
An insulin pump provides a small continuous dose of short-duration
(rapid- or short-acting) insulin subcutaneously throughout the day and
night. The client can self-administer an additional bolus dose from the
pump before each meal as needed. Short-duration insulin is used in an
insulin pump. An external pump is not attached surgically to the
pancreas.
Page 3 of 96
, NCLEX-RN 2026 Questions
A client with a diagnosis of diabetic ketoacidosis (DKA) is being treated
in the emergency department. Which findings support this diagnosis?
Select all that apply.
A. Increase in pH
B. Comatose state
C. Deep, rapid breathing
D. Decreased urine output
E. Elevated blood glucose level
B, C, E
Rationale:
Because of the profound deficiency of insulin associated with DKA,
glucose cannot be used for energy and the body breaks down fat as a
secondary source of energy. Ketones, which are acid by-products of fat
metabolism, build up, and the client experiences a metabolic
ketoacidosis. High serum glucose contributes to an osmotic diuresis and
the client becomes severely dehydrated. If untreated, the client will
become comatose due to severe dehydration, acidosis, and electrolyte
imbalance. Kussmaul's respirations, the deep rapid breathing associated
with DKA, is a compensatory mechanism by the body. The body
attempts to correct the acidotic state by blowing off carbon dioxide
(CO2), which is an acid. In the absence of insulin, the client will
experience severe hyperglycemia. Option 1 is incorrect, because in
acidosis the pH would be low. Option 4 is incorrect because a high
serum glucose will result in an osmotic diuresis and the client will
experience polyuria.
The nurse teaches a client with diabetes mellitus about differentiating
between hypoglycemia and ketoacidosis. The client demonstrates an
understanding of the teaching by stating that a form of glucose should
Page 4 of 96
NCLEX-RN 2026 Questions with Correct
Answers Questions And Answers Practice
Questions with Solutions Newest | Already
Graded A+
A clinic nurse prepares a teaching plan for a client receiving an
antineoplastic medication. When implementing the plan, the nurse
should make which statement to the client?
A. "You can take aspirin as needed for headache."
B. "You can drink beverages containing alcohol in moderate amounts
each evening."
C. "You need to consult with the primary health care provider (PHCP)
before receiving immunizations."
D. "It is fine to receive a flu vaccine at the local health fair without PHCP
approval because the flu is so contagious."
C
Rationale:
Because antineoplastic medications lower the resistance of the body,
clients must be informed not to receive immunizations without the
PHCP's approval. Clients also need to avoid contact with individuals who
have recently received a live virus vaccine. Clients need to avoid aspirin
and aspirin-containing products to minimize the risk of bleeding, and
they need to avoid alcohol to minimize the risk of toxicity and
side/adverse effects.
The nurse is analyzing the laboratory results of a client with leukemia
who has received a regimen of chemotherapy. Which laboratory value
Page 1 of 96
, NCLEX-RN 2026 Questions
would the nurse specifically note as a result of the massive cell
destruction that occurred from the chemotherapy?
A. Anemia
B. Decreased platelets
C. Increased uric acid level
D. Decreased leukocyte count
C
Rationale:
Hyperuricemia is especially common following treatment for leukemias
and lymphomas, because chemotherapy results in massive cell kill.
Although options 1, 2, and 4 also may be noted, an increased uric acid
level is related specifically to cell destruction.
A client is brought to the emergency department in an unresponsive
state, and a diagnosis of hyperosmolar hyperglycemic syndrome is
made. The nurse would immediately prepare to initiate which
anticipated primary health care provider's prescription?
A. Endotracheal intubation
B. 100 units of NPH insulin
C. Intravenous infusion of normal saline
D. Intravenous infusion of sodium bicarbonate
C
Rationale:
The primary goal of treatment in hyperosmolar hyperglycemic
syndrome (HHS) is to rehydrate the client to restore fluid volume and to
correct electrolyte deficiency. Intravenous (IV) fluid replacement is
Page 2 of 96
, NCLEX-RN 2026 Questions
similar to that administered in diabetic ketoacidosis (DKA) and begins
with IV infusion of normal saline. Regular insulin, not NPH insulin,
would be administered. The use of sodium bicarbonate to correct
acidosis is avoided because it can precipitate a further drop in serum
potassium levels. Intubation and mechanical ventilation are not
required to treat HHS.
An external insulin pump is prescribed for a client with diabetes
mellitus. When the client asks the nurse about the functioning of the
pump, the nurse bases the response on which information about the
pump?
A. It is timed to release programmed doses of either short-duration or
NPH insulin into the bloodstream at specific intervals.
B. It continuously infuses small amounts of NPH insulin into the
bloodstream while regularly monitoring blood glucose levels.
C. It is surgically attached to the pancreas and infuses regular insulin
into the pancreas. This releases insulin into the bloodstream. D. It
administers a small continuous dose of short-duration insulin
subcutaneously. The client can self-administer an additional bolus dose
from the pump before each meal.
D
Rationale:
An insulin pump provides a small continuous dose of short-duration
(rapid- or short-acting) insulin subcutaneously throughout the day and
night. The client can self-administer an additional bolus dose from the
pump before each meal as needed. Short-duration insulin is used in an
insulin pump. An external pump is not attached surgically to the
pancreas.
Page 3 of 96
, NCLEX-RN 2026 Questions
A client with a diagnosis of diabetic ketoacidosis (DKA) is being treated
in the emergency department. Which findings support this diagnosis?
Select all that apply.
A. Increase in pH
B. Comatose state
C. Deep, rapid breathing
D. Decreased urine output
E. Elevated blood glucose level
B, C, E
Rationale:
Because of the profound deficiency of insulin associated with DKA,
glucose cannot be used for energy and the body breaks down fat as a
secondary source of energy. Ketones, which are acid by-products of fat
metabolism, build up, and the client experiences a metabolic
ketoacidosis. High serum glucose contributes to an osmotic diuresis and
the client becomes severely dehydrated. If untreated, the client will
become comatose due to severe dehydration, acidosis, and electrolyte
imbalance. Kussmaul's respirations, the deep rapid breathing associated
with DKA, is a compensatory mechanism by the body. The body
attempts to correct the acidotic state by blowing off carbon dioxide
(CO2), which is an acid. In the absence of insulin, the client will
experience severe hyperglycemia. Option 1 is incorrect, because in
acidosis the pH would be low. Option 4 is incorrect because a high
serum glucose will result in an osmotic diuresis and the client will
experience polyuria.
The nurse teaches a client with diabetes mellitus about differentiating
between hypoglycemia and ketoacidosis. The client demonstrates an
understanding of the teaching by stating that a form of glucose should
Page 4 of 96
