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HESI A2 Version 2 Biology Exam Practice Questions and Answers | HESI A2 Biology Review | Rationales and Complete Exam Preparation | Latest 2026/2027 Update

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HESI A2 Version 2 Biology Exam Practice Questions and Answers | HESI A2 Biology Review | Rationales and Complete Exam Preparation | Latest 2026/2027 Update Description This comprehensive HESI A2 Biology Exam Practice Set contains 200 multiple-choice questions (MCQs) with correct answers marked with and detailed rationales for complete exam preparation. It covers all major HESI A2 Biology content areas including biomolecules, cellular structure, cell cycle, DNA and protein synthesis, genetics, metabolism, body systems, and ecology. Perfect for nursing school entrance exam review, this set is aligned with the latest 2026/2027 HESI A2 test blueprint. Keywords HESI A2 Biology, HESI A2 exam, HESI A2 practice questions, HESI A2 review, biology MCQs, nursing entrance exam, biomolecules, cell structure, DNA, protein synthesis, genetics, body systems, metabolism, HESI 2026, HESI 2027, HESI A2 study guide, HESI A2 Version 2 SECTION 1: BIOMOLECULES AND BASIC CHEMISTRY (Questions 1–25) 1. Which of the following is the primary function of carbohydrates in the human body? A. Long-term energy storage B. Immediate energy source C. Enzyme catalysis D. Genetic information storage Correct Answer: B Rationale: Carbohydrates, especially glucose, are the body's preferred immediate energy source. They are broken down quickly during cellular respiration. Lipids are used for long-term energy storage, proteins function as enzymes, and nucleic acids store genetic information. 2. Which biomolecule is composed of amino acids linked by peptide bonds? A. Carbohydrates B. Lipids C. Proteins D. Nucleic acids Correct Answer: C Rationale: Proteins are polymers of amino acids joined by peptide bonds. Carbohydrates are made of monosaccharides, lipids of glycerol and fatty acids, and nucleic acids of nucleotides. 3. What is the monomer of a nucleic acid? A. Monosaccharide B. Amino acid C. Nucleotide D. Fatty acid Correct Answer: C Rationale: Nucleic acids (DNA and RNA) are polymers of nucleotides, each consisting of a phosphate group, a five-carbon sugar, and a nitrogenous base. 4. Which of the following is NOT a function of lipids? A. Insulation B. Long-term energy storage C. Carrying genetic information D. Forming cell membranes Correct Answer: C Rationale: Carrying genetic information is the function of nucleic acids, not lipids. Lipids function in insulation, energy storage, and membrane formation (phospholipid bilayer). 5. Which element is found in all organic compounds? A. Nitrogen B. Carbon C. Phosphorus D. Sulfur Correct Answer: B Rationale: Carbon is the backbone of all organic compounds due to its ability to form four covalent bonds. 6. A solution with a pH of 3 is considered: A. Neutral B. Basic C. Acidic D. Alkaline Correct Answer: C Rationale: A pH below 7 is acidic. A pH of 7 is neutral, and above 7 is basic/alkaline. 7. Which of the following is a disaccharide? A. Glucose B. Sucrose C. Starch D. Glycogen Correct Answer: B Rationale: Sucrose (table sugar) is a disaccharide made of glucose and fructose. Glucose is a monosaccharide; starch and glycogen are polysaccharides. 8. Enzymes are best described as: A. Lipids that store energy B. Proteins that speed up chemical reactions C. Carbohydrates that provide structure D. Nucleic acids that carry information Correct Answer: B Rationale: Enzymes are biological catalysts, typically proteins, that lower activation energy and speed up biochemical reactions without being consumed. 9. Which bond holds the two strands of DNA together?

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HESI A2 Version 2 Biology Exam
Practice Questions and Answers | HESI
A2 Biology Review | Rationales and
Complete Exam Preparation | Latest
2026/2027 Update
Description

This comprehensive HESI A2 Biology Exam Practice Set contains 200 multiple-choice
questions (MCQs) with correct answers marked with ✅ and detailed rationales for
complete exam preparation. It covers all major HESI A2 Biology content areas including
biomolecules, cellular structure, cell cycle, DNA and protein synthesis, genetics,
metabolism, body systems, and ecology. Perfect for nursing school entrance exam
review, this set is aligned with the latest 2026/2027 HESI A2 test blueprint.


Keywords

HESI A2 Biology, HESI A2 exam, HESI A2 practice questions, HESI A2 review,
biology MCQs, nursing entrance exam, biomolecules, cell structure, DNA, protein
synthesis, genetics, body systems, metabolism, HESI 2026, HESI 2027, HESI A2
study guide, HESI A2 Version 2




SECTION 1: BIOMOLECULES AND BASIC CHEMISTRY
(Questions 1–25)

,1. Which of the following is the primary function of carbohydrates in the human
body?

A. Long-term energy storage
B. Immediate energy source
C. Enzyme catalysis
D. Genetic information storage

Correct Answer: B ✅

Rationale: Carbohydrates, especially glucose, are the body's preferred immediate
energy source. They are broken down quickly during cellular respiration. Lipids are used
for long-term energy storage, proteins function as enzymes, and nucleic acids store
genetic information.




2. Which biomolecule is composed of amino acids linked by peptide bonds?

A. Carbohydrates
B. Lipids
C. Proteins
D. Nucleic acids

Correct Answer: C ✅

Rationale: Proteins are polymers of amino acids joined by peptide bonds.
Carbohydrates are made of monosaccharides, lipids of glycerol and fatty acids, and
nucleic acids of nucleotides.

,3. What is the monomer of a nucleic acid?

A. Monosaccharide
B. Amino acid
C. Nucleotide
D. Fatty acid

Correct Answer: C ✅

Rationale: Nucleic acids (DNA and RNA) are polymers of nucleotides, each consisting
of a phosphate group, a five-carbon sugar, and a nitrogenous base.




4. Which of the following is NOT a function of lipids?

A. Insulation
B. Long-term energy storage
C. Carrying genetic information
D. Forming cell membranes

Correct Answer: C ✅

Rationale: Carrying genetic information is the function of nucleic acids, not lipids.
Lipids function in insulation, energy storage, and membrane formation (phospholipid
bilayer).




5. Which element is found in all organic compounds?

A. Nitrogen
B. Carbon

, C. Phosphorus
D. Sulfur

Correct Answer: B ✅

Rationale: Carbon is the backbone of all organic compounds due to its ability to form
four covalent bonds.




6. A solution with a pH of 3 is considered:

A. Neutral
B. Basic
C. Acidic
D. Alkaline

Correct Answer: C ✅

Rationale: A pH below 7 is acidic. A pH of 7 is neutral, and above 7 is basic/alkaline.




7. Which of the following is a disaccharide?

A. Glucose
B. Sucrose
C. Starch
D. Glycogen

Correct Answer: B ✅

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