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BIOL_252_Human_Anatomy_Physiology_II_250_Question_Review

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This BIOL 252 Human Anatomy and Physiology II review resource contains 250 practice questions designed to strengthen mastery of human body structures and physiological processes. Content focuses on systems including cardiovascular, respiratory, digestive, urinary, reproductive, endocrine, and immune systems. Questions encourage learners to connect anatomical structures with functions, understand physiological regulation, analyze interactions between body systems, and apply concepts to biological and clinical situations. Practice helps identify knowledge gaps, reinforce difficult concepts, and develop critical-thinking and problem-solving skills. The resource supports examination preparation by strengthening recall, conceptual understanding, system integration, and confidence when applying anatomy and physiology principles to assessment questions effectively.

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BIOL 252 Human Anatomy & Physiology II w/Lab | Final Exam
Review 90+ Questions and Answers -Summary | LockDown Browser
| Portage Learning
250-Question Original Practice Review • Answer key embedded • Built from the current BIOL 252 course outcomes and lab objectives
Heart schematic




R atrium → R ventricle → lungs L atrium → L ventricle → aorta
Respiratory schematic




Air: nose → pharynx → larynx → trachea → bronchi → alveoli


Module 1 — Blood
1. Which plasma protein contributes most directly to colloid osmotic pressure?
• Immunoglobulin E
• Hemoglobin
• Fibrin
■ Albumin
2. Which leukocyte is typically the most abundant circulating white blood cell?
• Basophil
• Monocyte
■ Neutrophil
• Eosinophil
3. Which leukocyte is especially associated with parasitic infections and allergic responses?
■ Eosinophil
• Platelet
• Neutrophil
• Monocyte
4. Which leukocyte releases histamine and heparin during inflammatory responses?
• Lymphocyte
• Monocyte
■ Basophil
• Erythrocyte
5. Which leukocyte can leave the bloodstream and differentiate into a macrophage in tissues?
■ Monocyte
• Basophil
• Neutrophil
• Eosinophil
6. What is the major role of platelets in hemostasis?
• Destroying old erythrocytes
• Carrying oxygen
• Producing antibodies
■ Forming the initial platelet plug and supporting coagulation
7. The hormone erythropoietin most directly stimulates which process?
• Antibody secretion
• Fibrin breakdown
• Platelet destruction
■ Erythrocyte production


BIOL 252 • Original 250-question final review • Not an official Portage Learning exam Page 1

, 8. Which organ is the major source of erythropoietin in adults?
• Liver
■ Kidney
• Thymus
• Spleen
9. The heme portion of hemoglobin contains which mineral?
■ Iron
• Sodium
• Potassium
• Calcium
10. A patient with reduced hemoglobin would most directly have impaired:
• Blood clot formation
• Lymph flow
• Antibody specificity
■ Oxygen-carrying capacity
11. What is the first vascular response immediately after a small vessel is injured?
• Clot retraction
• RBC agglutination
■ Vascular spasm
• Fibrinolysis
12. What is the purpose of the platelet plug?
• Dissolve fibrin
• Carry oxygen to the wound
■ Temporarily seal the damaged vessel
• Activate erythropoietin
13. Thrombin converts which soluble plasma protein into insoluble strands?
• Albumin
• Hemoglobin
• Globulin
■ Fibrinogen
14. Fibrin primarily functions to:
• Digest bacteria
• Carry carbon dioxide
• Prevent platelet adhesion
■ Form a mesh that stabilizes a blood clot
15. Which process removes a clot after vessel repair?
• Erythropoiesis
■ Fibrinolysis
• Hemolysis
• Agglutination
16. A substance that opposes coagulation is best described as a(n):
• Hemolytic agent
• Erythropoietin
■ Anticoagulant
• Agglutinogen
17. In ABO typing, agglutination with anti-A serum indicates the RBCs possess:
• Rh antigen only
• B antigen
• No surface antigens
■ A antigen
18. A person with type O-positive blood has which RBC antigen pattern?
• B antigen only; Rh present
• A and B antigens; Rh absent
■ No A or B antigens; Rh antigen present
• A antigen only; Rh absent
19. Which blood type is the usual universal red-cell donor type when ABO/Rh compatibility is required?
• A positive
■ O negative


BIOL 252 • Original 250-question final review • Not an official Portage Learning exam Page 2

, • B negative
• AB positive
20. Which blood type is the usual universal red-cell recipient type?
• A negative
• O negative
• B positive
■ AB positive
21. A hematocrit primarily estimates the proportion of blood occupied by:
• Plasma proteins
• Platelets
• Leukocytes
■ Erythrocytes
22. A complete blood count commonly includes all EXCEPT:
• RBC count
■ Serum bile acid concentration
• WBC count
• Platelet count
23. A low platelet count would most directly increase the risk of:
• Hyperoxygenation
• Hyperglycemia
■ Bleeding
• Hypertension
24. A low neutrophil count most directly reduces the body's ability to:
■ Respond rapidly to many bacterial infections
• Transport oxygen
• Filter plasma
• Form bile
25. Which condition describes abnormally low numbers of circulating erythrocytes or hemoglobin?
• Thrombocytosis
■ Anemia
• Polycythemia
• Leukocytosis
Blood-vessel wall schematic




Tunica intima | tunica media | tunica externa

26. Which condition refers to an abnormally high RBC mass or concentration?
• Leukopenia
■ Polycythemia
• Thrombocytopenia
• Anemia
27. Which laboratory result most directly reflects the oxygen-carrying pigment in blood?
• Hematocrit only
■ Hemoglobin concentration
• Platelet count
• WBC differential
28. Why are gloves and appropriate barriers used when handling blood in the laboratory?
■ To reduce exposure to bloodborne pathogens
• To sterilize the specimen
• To increase platelet production
• To prevent oxygen from entering blood

Module 2 — Cardiovascular System: The Heart
29. Which chamber pumps oxygenated blood into the aorta?
■ Left ventricle


BIOL 252 • Original 250-question final review • Not an official Portage Learning exam Page 3

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