Abrams' Clinical Drug Therapy:̣ Rationales for
Nursing Practice, 13th Edition, edited by
Geralyn Frandsen and Sandra Smith Pennington,
and published
̣ by Wolters Kluwer.
ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
,Abrams' Clinical Drug Therapy: ̣ Rationales for Nursing Practice, 13th Edition, edited by Geralyn Frandsen
and Sandra Smith Pennington, and published
̣ by Wolters Kluwer.
Chapter
̣ 1, The Foundation of Pharmacology: Quality and Safety
1. A woman diagnosed with obsessive–compulsive ̣ disorder has been prescribed
̣ oral
paroxetine
̣ hydrochloride. What is the exp ected
̣ effect for this p rescrip
̣ tion?
̣
A. Curative effect on symptoms
̣
B. Systemic effect on symptomṣ
C. Local effect on symptoms
̣
D. Parenteral effect on symptomṣ
ANS: B
Rationale: Drugs that produce
̣ systemic effects are taken into the body, circulated through
the bloodstream to their sites of action in various body tissues, and eventually eliminated
from the body. Curative agents are given to cure a disease process.
̣ In this case, paroxetine
̣
hydrochloride will control the symptoms ̣ but not cure the disorder. Drugs with local effects,
such as sunscreen and local anesthetics, act mainly at the site of app̣ lication.
̣ Paroxetine
hydrochloride is not administered parenterally.
̣ Parenteral agents are administered
subcutaneously, intramuscularly, or intravenously.
PTS: 1 REF: p.̣ 3, Introduction OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
̣
TOP: Chapter:
̣ 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple
̣ Choice
2. A client has been prescribed
̣ an antibiotic. This medication is a naturally occurring
substance that has been cheG
mRicA
alDlyEm
SoBdOifOieSd.TWhaOt M
.C is another name for this typẹ of
medication?
A. Synthetic drug
B. Semisynthetic drug
C. Biotechnology drug
D. Prototypẹ drug
ANS: B
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances
that have been chemically modified. Synthetic drugs are more standardized in their chemical
characteristics, more consistent in their effects, and less likely to produce
̣ allergic reactions.
Biotechnology drugs involve manipulating
̣ DNA and RNA and recombining genes into
hybrid molecules that can be inserted into living organisms. Prototypẹ drugs are the first
drug of a particular
̣ group ̣ to be developed.
̣
PTS: 1 REF: p.̣ 3, Drug Sources OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
̣
TOP: Chapter:
̣ 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple
̣ Choice
3. Which classification app̣ lies
̣ to morphine?
̣
A. Central nervous system depressant
̣
B. Central nervous system stimulant
ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
, C. Anti-inflammatory
D. Antihypertensive
̣
ANS: A
Rationale: Drugs are classified according to their effects on particular
̣ body systems, their
therapeutic
̣ uses, and their chemical characteristics. Morp hine
̣ is classified as a central
nervous system depressant
̣ and will produce
̣ this effect in the client. A central nervous
system stimulant increases attention and raises mood. An anti-inflammatory agent decreases
inflammation at the site of tissue or joint inflammation. An antihypertensive
̣ agent reduces
blood pressure.
̣
PTS: 1 REF: p.̣ 3, Drug Classifications and Prototypes
̣
OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
̣
TOP: Chapter:
̣ 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember NOT: Multiplẹ Choice
G R A D E S B O O S T . C O M
4. A client is administered amoxicillin. The generic name of this medication belongs to which
drug group?̣
A. Selective serotonin reuptake
̣ inhibitors
B. Diuretics
C. Penicillins
D. ACE inhibitors
ANS: C
Rationale: The generic name often indicates the drug group ̣ (e.g., drugs with generic names
GRADESBOOST.COM
ending in “cillin” are penicillins).
̣ Selective serotonin reuptake
̣ inhibitors are medications
that have antidepressant
̣ effects; SSRI is a broad classification, not a generic name. Diuretics
are medications that increase urine output; ̣ diuretic is a broad classification, not a generic
name. ACE inhibitor is the broad classification for the angiotensin receptor ̣ blockers, not the
generic name.
PTS: 1 REF: p.̣ 3, Drug Names OBJ: 2
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
̣
TOP: Chapter:
̣ 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple
̣ Choice
5. The administration of diphenhydramine
̣ is regulated by which U.S. government agency?
A. Public Health Service
B. Federal Trade Commission
C. Occupational
̣ Safety and Health Administration
D. Food and Drug Administration
ANS: D
ABRAMS' CLINICAL DRUG THERAPY:
, GRADESBOOST.COM
Rationale: The Food and Drug Administration app̣ roves ̣ drugs for over-the-counter
availability, including the transfer of drugs from prescrip
̣ tion
̣ to OTC status, and may
require clinical trials to determine the safety and effectiveness of OTC use. The Public
Health Service is regulated by the state to maintain the health of individual citizens of the
state. The Federal Trade Commission regulates imports ̣ and exports
̣ throughout the nation.
The Occupational
̣ Safety and Health Administration regulates safety within the workplace.
̣
PTS: 1 REF: p.̣ 4, Prescription
̣ and Nonprescrip
̣ tion
̣ Drugs
OBJ: 4
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
̣
TOP: Chapter:
̣ 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiplẹ Choice
6. In the U.S., the administration of anabolic steroids is regulated by which law?
A. The Food, Drug, and Cosmetic Act of 1938
B. The Comprehensive
̣ Drug Abuse Prevention and Control Act
C. The Harrison Narcotic Act
G R A D E S B O O S T . C O M
D. The Sherley Amendment
ANS: B
Rationale: The Comprehensive
̣ Drug Abuse Prevention and Control Act regulates the
manufacture and distribution of narcotics, stimulants, depressants,
̣ hallucinogens, and
anabolic steroids. The Food, Drug, and Cosmetic Act of 1938 revised and broadened FDA
powers
̣ and responsibilities,
̣ giving the FDA control over drug safety. The Harrison Narcotic
Act restricted the importation,
̣ manufacture, sale, and use of opium,
̣ cocaine, marijuana, and
other drugs that the act defiG
neRdAaD
sEnaSrcBoO
tiO
csSTh.eCSOhM
.T erley Amendment of 1912 prohibited
̣
fraudulent claims of drug effectiveness.
PTS: 1 REF: p.̣ 4, Prescription
̣ and Nonprescrip
̣ tion
̣ Drugs
OBJ: 3
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
̣
TOP: Chapter:
̣ 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember NOT: Multiplẹ Choice
7. A nurse is responsible
̣ for maintaining an accurate count and record of the controlled
substances on the nursing division. This nursing action is regulated by which U.S. law or
agency?
A. The Food, Drug, and Cosmetic Act of 1938
B. The Public Health Service
C. The Drug Enforcement Administration
D. The Sherley Amendment
ANS: C
GRADESBOOST.COM #1 TEST BANKS WEBSITE
Nursing Practice, 13th Edition, edited by
Geralyn Frandsen and Sandra Smith Pennington,
and published
̣ by Wolters Kluwer.
ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
,Abrams' Clinical Drug Therapy: ̣ Rationales for Nursing Practice, 13th Edition, edited by Geralyn Frandsen
and Sandra Smith Pennington, and published
̣ by Wolters Kluwer.
Chapter
̣ 1, The Foundation of Pharmacology: Quality and Safety
1. A woman diagnosed with obsessive–compulsive ̣ disorder has been prescribed
̣ oral
paroxetine
̣ hydrochloride. What is the exp ected
̣ effect for this p rescrip
̣ tion?
̣
A. Curative effect on symptoms
̣
B. Systemic effect on symptomṣ
C. Local effect on symptoms
̣
D. Parenteral effect on symptomṣ
ANS: B
Rationale: Drugs that produce
̣ systemic effects are taken into the body, circulated through
the bloodstream to their sites of action in various body tissues, and eventually eliminated
from the body. Curative agents are given to cure a disease process.
̣ In this case, paroxetine
̣
hydrochloride will control the symptoms ̣ but not cure the disorder. Drugs with local effects,
such as sunscreen and local anesthetics, act mainly at the site of app̣ lication.
̣ Paroxetine
hydrochloride is not administered parenterally.
̣ Parenteral agents are administered
subcutaneously, intramuscularly, or intravenously.
PTS: 1 REF: p.̣ 3, Introduction OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
̣
TOP: Chapter:
̣ 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple
̣ Choice
2. A client has been prescribed
̣ an antibiotic. This medication is a naturally occurring
substance that has been cheG
mRicA
alDlyEm
SoBdOifOieSd.TWhaOt M
.C is another name for this typẹ of
medication?
A. Synthetic drug
B. Semisynthetic drug
C. Biotechnology drug
D. Prototypẹ drug
ANS: B
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances
that have been chemically modified. Synthetic drugs are more standardized in their chemical
characteristics, more consistent in their effects, and less likely to produce
̣ allergic reactions.
Biotechnology drugs involve manipulating
̣ DNA and RNA and recombining genes into
hybrid molecules that can be inserted into living organisms. Prototypẹ drugs are the first
drug of a particular
̣ group ̣ to be developed.
̣
PTS: 1 REF: p.̣ 3, Drug Sources OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
̣
TOP: Chapter:
̣ 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple
̣ Choice
3. Which classification app̣ lies
̣ to morphine?
̣
A. Central nervous system depressant
̣
B. Central nervous system stimulant
ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
, C. Anti-inflammatory
D. Antihypertensive
̣
ANS: A
Rationale: Drugs are classified according to their effects on particular
̣ body systems, their
therapeutic
̣ uses, and their chemical characteristics. Morp hine
̣ is classified as a central
nervous system depressant
̣ and will produce
̣ this effect in the client. A central nervous
system stimulant increases attention and raises mood. An anti-inflammatory agent decreases
inflammation at the site of tissue or joint inflammation. An antihypertensive
̣ agent reduces
blood pressure.
̣
PTS: 1 REF: p.̣ 3, Drug Classifications and Prototypes
̣
OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
̣
TOP: Chapter:
̣ 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember NOT: Multiplẹ Choice
G R A D E S B O O S T . C O M
4. A client is administered amoxicillin. The generic name of this medication belongs to which
drug group?̣
A. Selective serotonin reuptake
̣ inhibitors
B. Diuretics
C. Penicillins
D. ACE inhibitors
ANS: C
Rationale: The generic name often indicates the drug group ̣ (e.g., drugs with generic names
GRADESBOOST.COM
ending in “cillin” are penicillins).
̣ Selective serotonin reuptake
̣ inhibitors are medications
that have antidepressant
̣ effects; SSRI is a broad classification, not a generic name. Diuretics
are medications that increase urine output; ̣ diuretic is a broad classification, not a generic
name. ACE inhibitor is the broad classification for the angiotensin receptor ̣ blockers, not the
generic name.
PTS: 1 REF: p.̣ 3, Drug Names OBJ: 2
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
̣
TOP: Chapter:
̣ 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple
̣ Choice
5. The administration of diphenhydramine
̣ is regulated by which U.S. government agency?
A. Public Health Service
B. Federal Trade Commission
C. Occupational
̣ Safety and Health Administration
D. Food and Drug Administration
ANS: D
ABRAMS' CLINICAL DRUG THERAPY:
, GRADESBOOST.COM
Rationale: The Food and Drug Administration app̣ roves ̣ drugs for over-the-counter
availability, including the transfer of drugs from prescrip
̣ tion
̣ to OTC status, and may
require clinical trials to determine the safety and effectiveness of OTC use. The Public
Health Service is regulated by the state to maintain the health of individual citizens of the
state. The Federal Trade Commission regulates imports ̣ and exports
̣ throughout the nation.
The Occupational
̣ Safety and Health Administration regulates safety within the workplace.
̣
PTS: 1 REF: p.̣ 4, Prescription
̣ and Nonprescrip
̣ tion
̣ Drugs
OBJ: 4
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
̣
TOP: Chapter:
̣ 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiplẹ Choice
6. In the U.S., the administration of anabolic steroids is regulated by which law?
A. The Food, Drug, and Cosmetic Act of 1938
B. The Comprehensive
̣ Drug Abuse Prevention and Control Act
C. The Harrison Narcotic Act
G R A D E S B O O S T . C O M
D. The Sherley Amendment
ANS: B
Rationale: The Comprehensive
̣ Drug Abuse Prevention and Control Act regulates the
manufacture and distribution of narcotics, stimulants, depressants,
̣ hallucinogens, and
anabolic steroids. The Food, Drug, and Cosmetic Act of 1938 revised and broadened FDA
powers
̣ and responsibilities,
̣ giving the FDA control over drug safety. The Harrison Narcotic
Act restricted the importation,
̣ manufacture, sale, and use of opium,
̣ cocaine, marijuana, and
other drugs that the act defiG
neRdAaD
sEnaSrcBoO
tiO
csSTh.eCSOhM
.T erley Amendment of 1912 prohibited
̣
fraudulent claims of drug effectiveness.
PTS: 1 REF: p.̣ 4, Prescription
̣ and Nonprescrip
̣ tion
̣ Drugs
OBJ: 3
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
̣
TOP: Chapter:
̣ 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember NOT: Multiplẹ Choice
7. A nurse is responsible
̣ for maintaining an accurate count and record of the controlled
substances on the nursing division. This nursing action is regulated by which U.S. law or
agency?
A. The Food, Drug, and Cosmetic Act of 1938
B. The Public Health Service
C. The Drug Enforcement Administration
D. The Sherley Amendment
ANS: C
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