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,Spirochete: Treponema pallidum
syphilis
• A painless lesion, a chancre, develops on the genitals
• The chancre may be present for up to 3-12
weeks 2-3 weeks after exposure
Primary stage of syphilis
• A rash develops on the trunk and extremities (hands andfeet)
• Contact with lesions can cause spread of infection
• Other s/s include: arthritis, meningitis, fever, malaise,and weight loss
Secondary stage of syphilis
causes progressive inflammatory changeswhich can impact multiple organ
• Manifestations include: aortitis and neurosyphilis(dementia, psychosis, paresis, stroke, or
meningitis)
Tertiary stage of syphilis
, Syphilis management
• Antibiotics are the primary method of treatment
• Penicillin G is the first line choice
• If allergic, doxycycline is alternate
• Most common in women 15-24 yrs old
• Often asymptomatic• s/s include
• Women: purulent discharge in the endocervical canal, UTI s/s, and vaginitis• --Men:
s/s are more common, burning on urination, penile discharge, painful/swollen testis
Chlamydia and gonorrhea
• Flagellated protozoan
• Per the CDC, about 3.7 million cases per year inthe US
• Can be asymptomatic which increases chancesof spread
• Increases risk for HIV, pregnancycomplications, infertility, and PID
• May lead to cervical cellular changes
• S/S include: malodorous vaginal discharge(may be frothy and discolored),
and vulvitismay occur leading to burning and itching
Trichomoniasis
Metronidazole or Tinidazole are
treatments for trichomoniasis
HSV-1 (genital herpes)