NR 293
NR 293 EXAM 2 REVIEW QUESTIONS AND ANSWERS
What are coagulation modifiers? - correct answer Coagulation modifiers
are a category of medications that both promote and prevent clot
formation as well as lysing a preformed clot and reversing the action of
anticoagulants.
Which medications are coagulation modifier drugs? - correct answer 1.
Apixaban
2. Aspirin
3. Heparin
4. Warfarin
What type of drug is Warfarin? - correct answer Warfarin is an
anticoagulant medication whose mechanism of action is to prevent clot
formation by inhibiting particular clotting factors.
What is hemostasis? - correct answer Refers to any process that stops
bleeding by any of these means:
,NR 293
mechanical- compression
surgical- clamping, cauterization
pharmacologic- coagulation modifier drugs
What is coagulation? - correct answer is the process by which an intrinsic
(internal damage to a blood vessel) or extrinsic injury (external damage
to the blood vessel) to a blood vessel triggers one of two pathways
depending on the injury.
Clotting is triggered by ______ - correct answer Clotting is triggered by an
injury to a blood vessel, which then triggers a cascade in which clotting
factors are activated. This results in a large concentration of fibrin.
Reverse of the Coagulation Process - correct answer The reverse of the
coagulation process is the fibrinolytic system. Fibrinolysis is the
breakdown of thrombi. This is an important part of hemostasis in order
to prevent excessive coagulation, blocked blood vessels, or mobilized
thrombi called emboli.
The coagulation modifier drugs are broken down into several subclasses
or categories based on their hemostasis reversal or promotion action.
Which items are mechanisms of action for this class of drug? - correct
answer 1. Lysing of a performed thrombus.
2. Thrombus promotion.
3. Anticoagulation reversal.
,NR 293
4. Thrombus prevention.
Categories that reduce or eliminate clots - correct answer 1.
Anticoagulants
2. Antiplatelets
3. Thrombolytics
Categories that increase clotting - correct answer 1. Antifibrinolytics
2. Hemorheologics
3. Reversal Drugs
What are anticoagulants? - correct answer Also known as antithrombotics
which are given to prevent clot formation in high-risk individuals who
may not respond to antiplatelet therapy. Common in those with atrial
fibrillation.
Anticoagulant Mechanism of Action - correct answer Prevents clot
formation by inhibiting specific clotting factors.
Anticoagulant Drug Classes - correct answer 1. Heparins
2. Coumarins
3. Direct Thrombin Inhibitors
4. Selective Factor Xa Inhibitors
, NR 293
Anticoagulant Common Drugs - correct answer 1. Heparin
2. Enoxaparin
3. Warfarin
4. Dabigatran
5. Rivaroxaban
6. Apixaban
Antiplatelets Mechanism of Action - correct answer Prevent clot formation
by interfering with platelet function. Given to prevent further clotting or
to prevent a stroke or heart attack. Also given during or after cardiac
stent placements.
Antiplatelet Drug Classes - correct answer 1. Aggregation Inhibitors
2. Glycoprotein llb/llla Inhibitors
Antiplatelet Common Drugs - correct answer 1. Clopidogrel
2. Ticagrelor
3. Aspirin
4. Abciximab
5. Tirofiban
6. Eptifibatide
NR 293 EXAM 2 REVIEW QUESTIONS AND ANSWERS
What are coagulation modifiers? - correct answer Coagulation modifiers
are a category of medications that both promote and prevent clot
formation as well as lysing a preformed clot and reversing the action of
anticoagulants.
Which medications are coagulation modifier drugs? - correct answer 1.
Apixaban
2. Aspirin
3. Heparin
4. Warfarin
What type of drug is Warfarin? - correct answer Warfarin is an
anticoagulant medication whose mechanism of action is to prevent clot
formation by inhibiting particular clotting factors.
What is hemostasis? - correct answer Refers to any process that stops
bleeding by any of these means:
,NR 293
mechanical- compression
surgical- clamping, cauterization
pharmacologic- coagulation modifier drugs
What is coagulation? - correct answer is the process by which an intrinsic
(internal damage to a blood vessel) or extrinsic injury (external damage
to the blood vessel) to a blood vessel triggers one of two pathways
depending on the injury.
Clotting is triggered by ______ - correct answer Clotting is triggered by an
injury to a blood vessel, which then triggers a cascade in which clotting
factors are activated. This results in a large concentration of fibrin.
Reverse of the Coagulation Process - correct answer The reverse of the
coagulation process is the fibrinolytic system. Fibrinolysis is the
breakdown of thrombi. This is an important part of hemostasis in order
to prevent excessive coagulation, blocked blood vessels, or mobilized
thrombi called emboli.
The coagulation modifier drugs are broken down into several subclasses
or categories based on their hemostasis reversal or promotion action.
Which items are mechanisms of action for this class of drug? - correct
answer 1. Lysing of a performed thrombus.
2. Thrombus promotion.
3. Anticoagulation reversal.
,NR 293
4. Thrombus prevention.
Categories that reduce or eliminate clots - correct answer 1.
Anticoagulants
2. Antiplatelets
3. Thrombolytics
Categories that increase clotting - correct answer 1. Antifibrinolytics
2. Hemorheologics
3. Reversal Drugs
What are anticoagulants? - correct answer Also known as antithrombotics
which are given to prevent clot formation in high-risk individuals who
may not respond to antiplatelet therapy. Common in those with atrial
fibrillation.
Anticoagulant Mechanism of Action - correct answer Prevents clot
formation by inhibiting specific clotting factors.
Anticoagulant Drug Classes - correct answer 1. Heparins
2. Coumarins
3. Direct Thrombin Inhibitors
4. Selective Factor Xa Inhibitors
, NR 293
Anticoagulant Common Drugs - correct answer 1. Heparin
2. Enoxaparin
3. Warfarin
4. Dabigatran
5. Rivaroxaban
6. Apixaban
Antiplatelets Mechanism of Action - correct answer Prevent clot formation
by interfering with platelet function. Given to prevent further clotting or
to prevent a stroke or heart attack. Also given during or after cardiac
stent placements.
Antiplatelet Drug Classes - correct answer 1. Aggregation Inhibitors
2. Glycoprotein llb/llla Inhibitors
Antiplatelet Common Drugs - correct answer 1. Clopidogrel
2. Ticagrelor
3. Aspirin
4. Abciximab
5. Tirofiban
6. Eptifibatide
