UWORLD NAPLEX ;COMPOUNDING 1-3 |ACTUAL
QUESTIONS AND VERIFIED ANSWERS|BRAND NEW
2026-2027 UPDATE|GRADED A+
Question 1
Which of the following statements are correct regarding the operation of a horizontal
laminar airflow workbench?
A- If power is interrupted, the hood can be used immediately for compounding
B- The hood must be operating continuously during compounding activity
C- The hood can be turned off for a maximum of 8 hours
D- If the hood is turned off, it must be on for at least 30 minutes before it can be used for
compounding
E- The hood must be turned off any time it is not being used for compounding activity
CORRECT ANSWER
B- The hood must be operating continuously during compounding activity
D- If the hood is turned off, it must be on for at least 30 minutes before it can be used for
compounding
**Primary engineering controls must be operating continuously during compounding
activity. If the power has been off, in addition to cleaning and disinfecting, the primary
engineering control must be on for at least 30 minutes before compounding can begin
1
@THE STUDY VAULT
,Question 2
USP requires periodic testing of the surfaces involved in sterile compounding. Which of the
following statements concerning surface testing is/are accurate? Select all that apply.
A- Testing should occur at the end of the day
B- Surfaces regularly exposed to staff should be tested
C- At least one surface sample must be taken from each ISO 5, 7, and 8 area
D- Action must be taken if any colony-forming units (CFUs) are identified
E- Tryptic soy agar (TSA) is used as the growth medium
CORRECT ANSWER
A- Testing should occur at the end of the day
B- Surfaces regularly exposed to staff should be tested
C- At least one surface sample must be taken from each ISO 5, 7, and 8 area
E- Tryptic soy agar (TSA) is used as the growth medium
**Action must be taken one OVER 3 CFUs are identified in the ISO 5 area, OVER 5 CFUs in
the ISO 7 area, or OVER 100 CFUs in an ISO 8 area
Question 3
Where do the pharmacy personnel don garb for sterile compounding?
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@THE STUDY VAULT
,A- Primary engineering control
B- Buffer room
C- Wash and Storage Area
D- Biological Safety Cabinet
E- Anteroom
CORRECT ANSWER
E- Anteroom
**Handwashing, garbing, CSP labeling and other procedures that release a high amount
of particulates are done in the anteroom
Question 4
During a 12 hour work shift preparing IV chemotherapy (assuming no breaks), what is the
minimum number of gowns that will be needed for the entire shift assuming that no
additional manufacturer information is available?
A- 1
B- 2
C- 3
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@THE STUDY VAULT
, D- 4
E- 5
CORRECT ANSWER
D- 4
**Gowns must be changed per the manufacturer's schedule. If no info is provided, gowns
should be changed every 2-3 hours and immediately after a spill or splash. Since the shift
is 12 hours and the gown must be changed every 3 hours, a minimum of 4 gowns will be
needed during the shift.
Question 5
Which of the following is used for disinfection while performing sanitization?
A- Sodium hypochlorite
B- Peroxide
C- Ammonia
D- 70% isopropyl alcohol
E- Sodium thiosulfate
CORRECT ANSWER
D- 70% isopropyl alcohol
**Disinfection is the final step in the sanitization process and uses 70% isopropyl alcohol
to inhibit or destroy microorganism growth. This step is required in sterile compounding.
4
@THE STUDY VAULT
QUESTIONS AND VERIFIED ANSWERS|BRAND NEW
2026-2027 UPDATE|GRADED A+
Question 1
Which of the following statements are correct regarding the operation of a horizontal
laminar airflow workbench?
A- If power is interrupted, the hood can be used immediately for compounding
B- The hood must be operating continuously during compounding activity
C- The hood can be turned off for a maximum of 8 hours
D- If the hood is turned off, it must be on for at least 30 minutes before it can be used for
compounding
E- The hood must be turned off any time it is not being used for compounding activity
CORRECT ANSWER
B- The hood must be operating continuously during compounding activity
D- If the hood is turned off, it must be on for at least 30 minutes before it can be used for
compounding
**Primary engineering controls must be operating continuously during compounding
activity. If the power has been off, in addition to cleaning and disinfecting, the primary
engineering control must be on for at least 30 minutes before compounding can begin
1
@THE STUDY VAULT
,Question 2
USP requires periodic testing of the surfaces involved in sterile compounding. Which of the
following statements concerning surface testing is/are accurate? Select all that apply.
A- Testing should occur at the end of the day
B- Surfaces regularly exposed to staff should be tested
C- At least one surface sample must be taken from each ISO 5, 7, and 8 area
D- Action must be taken if any colony-forming units (CFUs) are identified
E- Tryptic soy agar (TSA) is used as the growth medium
CORRECT ANSWER
A- Testing should occur at the end of the day
B- Surfaces regularly exposed to staff should be tested
C- At least one surface sample must be taken from each ISO 5, 7, and 8 area
E- Tryptic soy agar (TSA) is used as the growth medium
**Action must be taken one OVER 3 CFUs are identified in the ISO 5 area, OVER 5 CFUs in
the ISO 7 area, or OVER 100 CFUs in an ISO 8 area
Question 3
Where do the pharmacy personnel don garb for sterile compounding?
2
@THE STUDY VAULT
,A- Primary engineering control
B- Buffer room
C- Wash and Storage Area
D- Biological Safety Cabinet
E- Anteroom
CORRECT ANSWER
E- Anteroom
**Handwashing, garbing, CSP labeling and other procedures that release a high amount
of particulates are done in the anteroom
Question 4
During a 12 hour work shift preparing IV chemotherapy (assuming no breaks), what is the
minimum number of gowns that will be needed for the entire shift assuming that no
additional manufacturer information is available?
A- 1
B- 2
C- 3
3
@THE STUDY VAULT
, D- 4
E- 5
CORRECT ANSWER
D- 4
**Gowns must be changed per the manufacturer's schedule. If no info is provided, gowns
should be changed every 2-3 hours and immediately after a spill or splash. Since the shift
is 12 hours and the gown must be changed every 3 hours, a minimum of 4 gowns will be
needed during the shift.
Question 5
Which of the following is used for disinfection while performing sanitization?
A- Sodium hypochlorite
B- Peroxide
C- Ammonia
D- 70% isopropyl alcohol
E- Sodium thiosulfate
CORRECT ANSWER
D- 70% isopropyl alcohol
**Disinfection is the final step in the sanitization process and uses 70% isopropyl alcohol
to inhibit or destroy microorganism growth. This step is required in sterile compounding.
4
@THE STUDY VAULT
