UTA NURS 5315 UPDATED ACTUAL
QUESTIONS AND CORRECT ANSWERS
EXAM SCRIPT
●● what enzyme converts CO2 to Carbonic acid H2CO3
Answer: carbonic anhydrase
●● _________ is a byproduct of anaerobic metabolism of glucose
Answer: lactic acid
●● end product of oxidation of sulfur containing amino acids
Answer: sulfuric acid
●● end product of metabolism of phosphoproteins and ribonucleotides
which are used as an energy source
Answer: phosphoric acid
●● __________ binds with 40% of calcium
Answer: albumin
●● charge of albumin
Answer: negative
,●● what happens with albumin and calcium in acidotic states
Answer: There is an increased amount of H ions which causes albumin
to bind to more H ions and less calcium ions causing calcium ions to
become displaced leading to a higher level of free calcium
●● what happens with albumin and calcium in alkalotic states
Answer: There is a decreased amount of H ions causing a insufficient
amount of H ions to bind with albumin. This causes albumin to bind
with more calcium (due to H depletion) and causes a decreased amount
of free calcium
●● When the extracellular fluid volume is expanded it ____________
the reabsorption of HCO3 in the ____________ ___________
Answer: inhibits; proximal tubule
●● A deficit in ECF volume results in a __________ in the reabsorption
of HCO3
Answer: increase
●● What hormone does ECF volume deficit stimulate
Answer: RAAS
●● How does RAAS affect bicarb
, Answer: Angiotension II stimulates the Na-H exchanger in the proximal
tubule --> increases HCO3 reabsorption
●● Angiotension II stimulates the Na-H exchanger in the proximal
tubule --> increases HCO3 reabsorption --> what does this cause?
Answer: metabolic alkalosis (contraction alkalosis) secondary to volume
depletion- can occur with use of loop/thiazide diuretics
●● Where does the renal excretion of hydrogen occur?
Answer: distal tubule and collecting ducts
●● What 2 active transport system are used to secrete H
Answer: H-ATPase and H-K-ATPase
●● How do the 2 transport systems move H to be excreted
Answer: move H into the lumen and move potassium from the lumen
into the cells
●● once H is in the lumen what does it bind with?
Answer: monohydrogen phosphate (HPO4)
●● what does mono hydrogen phosphate produce
Answer: H2PO4 --> dihydrogen phosphate
QUESTIONS AND CORRECT ANSWERS
EXAM SCRIPT
●● what enzyme converts CO2 to Carbonic acid H2CO3
Answer: carbonic anhydrase
●● _________ is a byproduct of anaerobic metabolism of glucose
Answer: lactic acid
●● end product of oxidation of sulfur containing amino acids
Answer: sulfuric acid
●● end product of metabolism of phosphoproteins and ribonucleotides
which are used as an energy source
Answer: phosphoric acid
●● __________ binds with 40% of calcium
Answer: albumin
●● charge of albumin
Answer: negative
,●● what happens with albumin and calcium in acidotic states
Answer: There is an increased amount of H ions which causes albumin
to bind to more H ions and less calcium ions causing calcium ions to
become displaced leading to a higher level of free calcium
●● what happens with albumin and calcium in alkalotic states
Answer: There is a decreased amount of H ions causing a insufficient
amount of H ions to bind with albumin. This causes albumin to bind
with more calcium (due to H depletion) and causes a decreased amount
of free calcium
●● When the extracellular fluid volume is expanded it ____________
the reabsorption of HCO3 in the ____________ ___________
Answer: inhibits; proximal tubule
●● A deficit in ECF volume results in a __________ in the reabsorption
of HCO3
Answer: increase
●● What hormone does ECF volume deficit stimulate
Answer: RAAS
●● How does RAAS affect bicarb
, Answer: Angiotension II stimulates the Na-H exchanger in the proximal
tubule --> increases HCO3 reabsorption
●● Angiotension II stimulates the Na-H exchanger in the proximal
tubule --> increases HCO3 reabsorption --> what does this cause?
Answer: metabolic alkalosis (contraction alkalosis) secondary to volume
depletion- can occur with use of loop/thiazide diuretics
●● Where does the renal excretion of hydrogen occur?
Answer: distal tubule and collecting ducts
●● What 2 active transport system are used to secrete H
Answer: H-ATPase and H-K-ATPase
●● How do the 2 transport systems move H to be excreted
Answer: move H into the lumen and move potassium from the lumen
into the cells
●● once H is in the lumen what does it bind with?
Answer: monohydrogen phosphate (HPO4)
●● what does mono hydrogen phosphate produce
Answer: H2PO4 --> dihydrogen phosphate
