• ADVANCED
PHARMACOLOGY 09/18/2026
EXAM
WGU D116 ADVANCED PHARMACOLOGY FINAL
EXAM 2 OBJECTIVE ASSEMENT & PRE-ASSESMENT
700 QUESTIONS AND ANSWERS LATEST UPDATE
THIS YEAR - JUST RELEASED
10.) The clinic nurse is performing an admission assessment on a client. The nurse notes that the client is taking
azelaic acid (Azelex). Because of the medication prescription, the nurse would suspect that the client is being
treated for:
1. Acne
P 1
, • ADVANCED
PHARMACOLOGY 09/18/2026
EXAM
2. Eczema
3. Hair loss
4. Herpes simplex –
Correct Answer :1. Acne
Rationale:
Azelaic acid is a topical medication used to treat mild to moderate acne. The acid appears to work by
suppressing the growth of Propionibacterium acnes and decreasing the proliferation of keratinocytes. Options 2,
3, and 4 are incorrect.
.) The health care provider has prescribed silver sulfadiazine (Silvadene) for the client with a partial-thickness
burn, which has cultured positive for gram-negative bacteria. The nurse is reinforcing information to the client
about the medication. Which statement made by the client indicates a lack of understanding about the
treatments?
1. "The medication is an antibacterial."
2. "The medication will help heal the burn."
3. "The medication will permanently stain my skin."
4. "The medication should be applied directly to the wound." - Correct Answer :3. "The medication will
permanently stain my skin."
Rationale:
Silver sulfadiazine (Silvadene) is an antibacterial that has a broad spectrum of activity against gram-negative
bacteria, gram-positive bacteria, and yeast. It is applied directly to the wound to assist in healing. It does not
stain the skin.
.) A nurse is caring for a client who is receiving an intravenous (IV) infusion of an antineoplastic medication.
During the infusion, the client complains of pain at the insertion site. During an inspection of the site, the nurse
notes redness and swelling and that the rate of infusion of the medication has slowed. The nurse should take
which appropriate action?
1. Notify the registered nurse.
2. Administer pain medication to reduce the discomfort.
P 2
, • ADVANCED
PHARMACOLOGY 09/18/2026
EXAM
3. Apply ice and maintain the infusion rate, as prescribed.
4. Elevate the extremity of the IV site, and slow the infusion. - Correct Answer :1. Notify the registered nurse.
Rationale:
When antineoplastic medications (Chemotheraputic Agents) are administered via IV, great care must be taken
to prevent the medication from escaping into the tissues surrounding the injection site, because pain, tissue
damage, and necrosis can result. The nurse monitors for signs of extravasation, such as redness or swelling at
the insertion site and a decreased infusion rate. If extravasation occurs, the registered nurse needs to be
notified; he or she will then contact the health care provider.
.) The client with squamous cell carcinoma of the larynx is receiving bleomycin intravenously. The nurse caring for
the client anticipates that which diagnostic study will be prescribed?
1. Echocardiography
2. Electrocardiography
3. Cervical radiography
4. Pulmonary function studies - Correct Answer :4. Pulmonary function studies
Rationale:
Bleomycin is an antineoplastic medication (Chemotheraputic Agents) that can cause interstitial pneumonitis,
which can progress to pulmonary fibrosis. Pulmonary function studies along with hematological, hepatic, and
renal function tests need to be monitored. The nurse needs to monitor lung sounds for dyspnea and crackles,
which indicate pulmonary toxicity. The medication needs to be discontinued immediately if pulmonary toxicity
occurs. Options 1, 2, and 3 are unrelated to the specific use of this medication.
.) The client with acute myelocytic leukemia is being treated with busulfan (Myleran). Which laboratory value
would the nurse specifically monitor during treatment with this medication?
1. Clotting time
2. Uric acid level
3. Potassium level
4. Blood glucose level - Correct Answer :2. Uric acid level
Rationale:
P 3
, • ADVANCED
PHARMACOLOGY 09/18/2026
EXAM
Busulfan (Myleran) can cause an increase in the uric acid level. Hyperuricemia can produce uric acid
nephropathy, renal stones, and acute renal failure. Options 1, 3, and 4 are not specifically related to this
medication.
.) The client with small cell lung cancer is being treated with etoposide (VePesid). The nurse who is assisting in
caring for the client during its administration understands that which side effect is specifically associated with
this medication?
1. Alopecia
2. Chest pain
3. Pulmonary fibrosis
4. Orthostatic hypotension - Correct Answer :4. Orthostatic hypotension
Rationale:
A side effect specific to etoposide is orthostatic hypotension. The client's blood pressure is monitored during the
infusion. Hair loss occurs with nearly all the antineoplastic medications. Chest pain and pulmonary fibrosis are
unrelated to this medication.
.) The clinic nurse is reviewing a teaching plan for the client receiving an antineoplastic medication. When
implementing the plan, the nurse tells the client:
1. To take aspirin (acetylsalicylic acid) as needed for headache
2. Drink beverages containing alcohol in moderate amounts each evening
3. Consult with health care providers (HCPs) before receiving immunizations
4. That it is not necessary to consult HCPs before receiving a flu vaccine at the local health fair - Correct Answer
:3. Consult with health care providers (HCPs) before receiving immunizations
Rationale:
Because antineoplastic medications lower the resistance of the body, clients must be informed not to receive
immunizations without a HCP's approval. Clients also need to avoid contact with individuals who have recently
received a live virus vaccine. Clients need to avoid aspirin and aspirin-containing products to minimize the risk of
bleeding, and they need to avoid alcohol to minimize the risk of toxicity and side effects.
17.) The client with ovarian cancer is being treated with vincristine (Oncovin). The nurse monitors the client,
knowing that which of the following indicates a side effect specific to this medication?
P 4
PHARMACOLOGY 09/18/2026
EXAM
WGU D116 ADVANCED PHARMACOLOGY FINAL
EXAM 2 OBJECTIVE ASSEMENT & PRE-ASSESMENT
700 QUESTIONS AND ANSWERS LATEST UPDATE
THIS YEAR - JUST RELEASED
10.) The clinic nurse is performing an admission assessment on a client. The nurse notes that the client is taking
azelaic acid (Azelex). Because of the medication prescription, the nurse would suspect that the client is being
treated for:
1. Acne
P 1
, • ADVANCED
PHARMACOLOGY 09/18/2026
EXAM
2. Eczema
3. Hair loss
4. Herpes simplex –
Correct Answer :1. Acne
Rationale:
Azelaic acid is a topical medication used to treat mild to moderate acne. The acid appears to work by
suppressing the growth of Propionibacterium acnes and decreasing the proliferation of keratinocytes. Options 2,
3, and 4 are incorrect.
.) The health care provider has prescribed silver sulfadiazine (Silvadene) for the client with a partial-thickness
burn, which has cultured positive for gram-negative bacteria. The nurse is reinforcing information to the client
about the medication. Which statement made by the client indicates a lack of understanding about the
treatments?
1. "The medication is an antibacterial."
2. "The medication will help heal the burn."
3. "The medication will permanently stain my skin."
4. "The medication should be applied directly to the wound." - Correct Answer :3. "The medication will
permanently stain my skin."
Rationale:
Silver sulfadiazine (Silvadene) is an antibacterial that has a broad spectrum of activity against gram-negative
bacteria, gram-positive bacteria, and yeast. It is applied directly to the wound to assist in healing. It does not
stain the skin.
.) A nurse is caring for a client who is receiving an intravenous (IV) infusion of an antineoplastic medication.
During the infusion, the client complains of pain at the insertion site. During an inspection of the site, the nurse
notes redness and swelling and that the rate of infusion of the medication has slowed. The nurse should take
which appropriate action?
1. Notify the registered nurse.
2. Administer pain medication to reduce the discomfort.
P 2
, • ADVANCED
PHARMACOLOGY 09/18/2026
EXAM
3. Apply ice and maintain the infusion rate, as prescribed.
4. Elevate the extremity of the IV site, and slow the infusion. - Correct Answer :1. Notify the registered nurse.
Rationale:
When antineoplastic medications (Chemotheraputic Agents) are administered via IV, great care must be taken
to prevent the medication from escaping into the tissues surrounding the injection site, because pain, tissue
damage, and necrosis can result. The nurse monitors for signs of extravasation, such as redness or swelling at
the insertion site and a decreased infusion rate. If extravasation occurs, the registered nurse needs to be
notified; he or she will then contact the health care provider.
.) The client with squamous cell carcinoma of the larynx is receiving bleomycin intravenously. The nurse caring for
the client anticipates that which diagnostic study will be prescribed?
1. Echocardiography
2. Electrocardiography
3. Cervical radiography
4. Pulmonary function studies - Correct Answer :4. Pulmonary function studies
Rationale:
Bleomycin is an antineoplastic medication (Chemotheraputic Agents) that can cause interstitial pneumonitis,
which can progress to pulmonary fibrosis. Pulmonary function studies along with hematological, hepatic, and
renal function tests need to be monitored. The nurse needs to monitor lung sounds for dyspnea and crackles,
which indicate pulmonary toxicity. The medication needs to be discontinued immediately if pulmonary toxicity
occurs. Options 1, 2, and 3 are unrelated to the specific use of this medication.
.) The client with acute myelocytic leukemia is being treated with busulfan (Myleran). Which laboratory value
would the nurse specifically monitor during treatment with this medication?
1. Clotting time
2. Uric acid level
3. Potassium level
4. Blood glucose level - Correct Answer :2. Uric acid level
Rationale:
P 3
, • ADVANCED
PHARMACOLOGY 09/18/2026
EXAM
Busulfan (Myleran) can cause an increase in the uric acid level. Hyperuricemia can produce uric acid
nephropathy, renal stones, and acute renal failure. Options 1, 3, and 4 are not specifically related to this
medication.
.) The client with small cell lung cancer is being treated with etoposide (VePesid). The nurse who is assisting in
caring for the client during its administration understands that which side effect is specifically associated with
this medication?
1. Alopecia
2. Chest pain
3. Pulmonary fibrosis
4. Orthostatic hypotension - Correct Answer :4. Orthostatic hypotension
Rationale:
A side effect specific to etoposide is orthostatic hypotension. The client's blood pressure is monitored during the
infusion. Hair loss occurs with nearly all the antineoplastic medications. Chest pain and pulmonary fibrosis are
unrelated to this medication.
.) The clinic nurse is reviewing a teaching plan for the client receiving an antineoplastic medication. When
implementing the plan, the nurse tells the client:
1. To take aspirin (acetylsalicylic acid) as needed for headache
2. Drink beverages containing alcohol in moderate amounts each evening
3. Consult with health care providers (HCPs) before receiving immunizations
4. That it is not necessary to consult HCPs before receiving a flu vaccine at the local health fair - Correct Answer
:3. Consult with health care providers (HCPs) before receiving immunizations
Rationale:
Because antineoplastic medications lower the resistance of the body, clients must be informed not to receive
immunizations without a HCP's approval. Clients also need to avoid contact with individuals who have recently
received a live virus vaccine. Clients need to avoid aspirin and aspirin-containing products to minimize the risk of
bleeding, and they need to avoid alcohol to minimize the risk of toxicity and side effects.
17.) The client with ovarian cancer is being treated with vincristine (Oncovin). The nurse monitors the client,
knowing that which of the following indicates a side effect specific to this medication?
P 4
