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Introduction to Genetic Analysis
Anthony J.F. Griffiths, John Doebley, Catherine Peichel, and David A. Wassarman
12th Edition
PlusBay.Plus
,Table of Contents
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Chapter 01 The Genetics Revolution
tx tx tx tx 1
Chapter 02 Single Gene Inheritance
tx tx tx tx 6
Chapter 03 Independent Assortment of Genes
tx tx tx tx tx 26
Chapter 04 Mapping Eukaryote Chromosomes by Recombination
tx tx tx tx tx tx 43
Chapter 05 Gene Interaction
tx tx tx 63
Chapter 06 The Genetics of Bacteria and Their Viruses
tx tx tx tx tx tx tx tx 84
Chapter 07 DNA Structure and Replication
tx tx tx tx tx 104
Chapter 08 RNA Transcription Processing and Decay
tx tx tx tx tx tx 117
Chapter 09 Proteins and Their Synthesis
tx tx tx tx tx 130
Chapter 10 Gene Isolation and Manipulation
tx tx tx tx tx 141
Chapter 11 Regulation of Gene Expression in Bacteria and Their Viruses
tx tx tx tx tx tx tx tx tx tx 160
Chapter 12 Regulation of Gene Expression in Eukaryotes
tx tx tx tx tx tx tx 175
Chapter 13 The Genetic Control of Development
tx tx tx tx tx tx 184
Chapter 14 Genomes and Genomics
tx tx tx tx 192
Chapter 15 DNA Damage Repair and Recombination
tx tx tx tx tx tx 197
Chapter 16 The Dynamic Genome Transposable Elements
tx tx tx tx tx tx 216
Chapter 17 Large Scale Chromosomal Changes
tx tx tx tx tx 225
Chapter 18 Population Genetics
tx tx tx 243
Chapter 19 The Inheritance of Complex Traits
tx tx tx tx tx tx 258
Chapter 20 Evolution of Genes and Traits
tx tx tx tx tx tx 270
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Chapter 01: The Genetics Revolution
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1. The early 1900s was an important period for genetics due to which of the following major events?
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a. the rediscovery of Gregor Mendel's scientific findings
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b. Watson and Crick solving the structure of DNA tx tx tx tx tx tx tx
c. Walter Sutton and Theodore Boveri hypothesizing that chromosomes are the hereditary elements
tx tx tx tx tx tx tx tx tx tx tx
d. the rediscovery of Gregor Mendel's scientific findings and Walter Sutton and Theodore Boveri
tx tx tx tx tx tx tx tx tx tx tx tx tx
hypothesizing that chromosomes are the hereditary elements tx tx tx tx tx tx
e. All of the answer options are correct.
tx tx tx tx tx tx
ANSWER: e t x
2. A sample of normal double-
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stranded DNA was found to have a guanine content of 18%. What is the expected proportion of adenine?
tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx
a. 9%
b. 32%
c. 36%
d. 68%
e. 82%
ANSWER: b t x
3. In one strand of DNA, the nucleotide sequence is 5'-ATGC-
tx tx tx tx tx tx tx tx tx
3'. The complementary sequence in the other strand must be
tx tx tx tx tx tx tx tx tx
a. 3'-ATGC-5'.
b. 3'-TACG-5'.
c. 5'-ATCG-3'.
d. 5'-CGTA-3'.
e. 5'-TACG-3'.
ANSWER: b t x
4. How many different DNA molecules that are eight-nucleotide-pairs long are theoretically possible?
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a. 24
b. 32
c. 64
d. 256
e. 65,536
ANSWER: e t x
5. Which of the following is/are TRUE about genes?
tx tx tx tx tx tx tx
a. Genes are located on chromosomes. tx tx tx tx
b. Genes come in variants known as alleles. tx tx tx tx tx tx
c. Genes usually encode protein products. tx tx tx tx
d. All of the answer options are correct.
tx tx tx tx tx tx
e. None of the answer options is correct.
tx tx tx tx tx tx
ANSWER: d t x
1|Page
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6. Wild cats (Felis silvestris) and common mice (Mus musculus) are diploid. In wild cats, 2n = 38, while in
tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx
common mice, 2n = 40. Based on this information, we can conclude that wild-cat cells have
tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx
a. less DNA than common-mouse cells.
tx tx tx tx
b. smaller genomes than common-mouse cells. tx tx tx tx
c. fewer DNA molecules than common-mouse cells.
tx tx tx tx tx
d. fewer genes than common-mouse cells.
tx tx tx tx
e. fewer sets of chromosomes than common-mouse cells.
tx tx tx tx tx tx
ANSWER: c t x
7. Which of the following is a component of DNA?
tx tx tx tx tx tx tx tx
a. alanine
b. arginine
c. cysteine
d. guanine
e. tyrosine
ANSWER: d t x
8. Which of the following is/are TRUE of the DNA structure solved by Watson and Crick?
tx tx tx tx tx tx tx tx tx tx tx tx tx tx
a. It is a double-helical structure.
tx tx tx tx
b. Sugar–phosphate backbone is always toward the outside of the DNA. tx tx tx tx tx tx tx tx tx
c. There are two hydrogen bonds between A and T and three hydrogen bonds between C and G.
tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx
d. There are four types of nitrogenous bases.
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e. All of the answer options are correct.
tx tx tx tx tx tx
ANSWER: e t x
9. Which of the following is a CORRECT representation of the central dogma?
tx tx tx tx tx tx tx tx tx tx tx
a. RNA → DNA → protein tx tx tx tx
b. protein → DNA → RNA tx tx tx tx
c. DNA → RNA → protein tx tx tx tx
d. DNA → protein → DNA tx tx tx tx
e. None of the answer options is correct.
tx tx tx tx tx tx
ANSWER: c t x
10. You have come across a dog (named Cindy) that does not have a tail. Interestingly, all the puppies produced
tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx
by this dog don't have a tail. If the lack of tail is caused by a genetic mutation, where has this mutation most lik
tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx
ely taken place?
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a. in Cindy's gametes
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b. in the cells that should normally have given rise to Cindy's tail
tx tx tx tx tx tx tx tx tx tx tx
c. in the cells that should normally have given rise to Cindy's and her puppies' tails
tx tx tx tx tx tx tx tx tx tx tx tx tx tx
d. in all of Cindy's cells (including her gametes)
tx tx tx tx tx tx tx
e. in a gamete of one of Cindy's parents
tx tx tx tx tx tx tx
ANSWER: a t x
11. Which of the following features makes a species suitable as a model organism?
tx tx tx tx tx tx tx tx tx tx tx tx
2|Page
tx tx tx tx
PlusBay.Plus
Introduction to Genetic Analysis
Anthony J.F. Griffiths, John Doebley, Catherine Peichel, and David A. Wassarman
12th Edition
PlusBay.Plus
,Table of Contents
tx tx
Chapter 01 The Genetics Revolution
tx tx tx tx 1
Chapter 02 Single Gene Inheritance
tx tx tx tx 6
Chapter 03 Independent Assortment of Genes
tx tx tx tx tx 26
Chapter 04 Mapping Eukaryote Chromosomes by Recombination
tx tx tx tx tx tx 43
Chapter 05 Gene Interaction
tx tx tx 63
Chapter 06 The Genetics of Bacteria and Their Viruses
tx tx tx tx tx tx tx tx 84
Chapter 07 DNA Structure and Replication
tx tx tx tx tx 104
Chapter 08 RNA Transcription Processing and Decay
tx tx tx tx tx tx 117
Chapter 09 Proteins and Their Synthesis
tx tx tx tx tx 130
Chapter 10 Gene Isolation and Manipulation
tx tx tx tx tx 141
Chapter 11 Regulation of Gene Expression in Bacteria and Their Viruses
tx tx tx tx tx tx tx tx tx tx 160
Chapter 12 Regulation of Gene Expression in Eukaryotes
tx tx tx tx tx tx tx 175
Chapter 13 The Genetic Control of Development
tx tx tx tx tx tx 184
Chapter 14 Genomes and Genomics
tx tx tx tx 192
Chapter 15 DNA Damage Repair and Recombination
tx tx tx tx tx tx 197
Chapter 16 The Dynamic Genome Transposable Elements
tx tx tx tx tx tx 216
Chapter 17 Large Scale Chromosomal Changes
tx tx tx tx tx 225
Chapter 18 Population Genetics
tx tx tx 243
Chapter 19 The Inheritance of Complex Traits
tx tx tx tx tx tx 258
Chapter 20 Evolution of Genes and Traits
tx tx tx tx tx tx 270
PlusBay.Plus
, TesttxBanktx-txIntroductiontxtotxGenetictxAnalysis,tx12thtxEditiontx(Griffiths,tx2021)
Chapter 01: The Genetics Revolution
tx tx tx tx
1. The early 1900s was an important period for genetics due to which of the following major events?
tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx
a. the rediscovery of Gregor Mendel's scientific findings
tx tx tx tx tx tx
b. Watson and Crick solving the structure of DNA tx tx tx tx tx tx tx
c. Walter Sutton and Theodore Boveri hypothesizing that chromosomes are the hereditary elements
tx tx tx tx tx tx tx tx tx tx tx
d. the rediscovery of Gregor Mendel's scientific findings and Walter Sutton and Theodore Boveri
tx tx tx tx tx tx tx tx tx tx tx tx tx
hypothesizing that chromosomes are the hereditary elements tx tx tx tx tx tx
e. All of the answer options are correct.
tx tx tx tx tx tx
ANSWER: e t x
2. A sample of normal double-
tx tx tx tx
stranded DNA was found to have a guanine content of 18%. What is the expected proportion of adenine?
tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx
a. 9%
b. 32%
c. 36%
d. 68%
e. 82%
ANSWER: b t x
3. In one strand of DNA, the nucleotide sequence is 5'-ATGC-
tx tx tx tx tx tx tx tx tx
3'. The complementary sequence in the other strand must be
tx tx tx tx tx tx tx tx tx
a. 3'-ATGC-5'.
b. 3'-TACG-5'.
c. 5'-ATCG-3'.
d. 5'-CGTA-3'.
e. 5'-TACG-3'.
ANSWER: b t x
4. How many different DNA molecules that are eight-nucleotide-pairs long are theoretically possible?
tx tx tx tx tx tx tx tx tx tx tx
a. 24
b. 32
c. 64
d. 256
e. 65,536
ANSWER: e t x
5. Which of the following is/are TRUE about genes?
tx tx tx tx tx tx tx
a. Genes are located on chromosomes. tx tx tx tx
b. Genes come in variants known as alleles. tx tx tx tx tx tx
c. Genes usually encode protein products. tx tx tx tx
d. All of the answer options are correct.
tx tx tx tx tx tx
e. None of the answer options is correct.
tx tx tx tx tx tx
ANSWER: d t x
1|Page
tx tx tx tx
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, TesttxBanktx-txIntroductiontxtotxGenetictxAnalysis,tx12thtxEditiontx(Griffiths,tx2021)
6. Wild cats (Felis silvestris) and common mice (Mus musculus) are diploid. In wild cats, 2n = 38, while in
tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx
common mice, 2n = 40. Based on this information, we can conclude that wild-cat cells have
tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx
a. less DNA than common-mouse cells.
tx tx tx tx
b. smaller genomes than common-mouse cells. tx tx tx tx
c. fewer DNA molecules than common-mouse cells.
tx tx tx tx tx
d. fewer genes than common-mouse cells.
tx tx tx tx
e. fewer sets of chromosomes than common-mouse cells.
tx tx tx tx tx tx
ANSWER: c t x
7. Which of the following is a component of DNA?
tx tx tx tx tx tx tx tx
a. alanine
b. arginine
c. cysteine
d. guanine
e. tyrosine
ANSWER: d t x
8. Which of the following is/are TRUE of the DNA structure solved by Watson and Crick?
tx tx tx tx tx tx tx tx tx tx tx tx tx tx
a. It is a double-helical structure.
tx tx tx tx
b. Sugar–phosphate backbone is always toward the outside of the DNA. tx tx tx tx tx tx tx tx tx
c. There are two hydrogen bonds between A and T and three hydrogen bonds between C and G.
tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx
d. There are four types of nitrogenous bases.
tx tx tx tx tx tx
e. All of the answer options are correct.
tx tx tx tx tx tx
ANSWER: e t x
9. Which of the following is a CORRECT representation of the central dogma?
tx tx tx tx tx tx tx tx tx tx tx
a. RNA → DNA → protein tx tx tx tx
b. protein → DNA → RNA tx tx tx tx
c. DNA → RNA → protein tx tx tx tx
d. DNA → protein → DNA tx tx tx tx
e. None of the answer options is correct.
tx tx tx tx tx tx
ANSWER: c t x
10. You have come across a dog (named Cindy) that does not have a tail. Interestingly, all the puppies produced
tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx
by this dog don't have a tail. If the lack of tail is caused by a genetic mutation, where has this mutation most lik
tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx tx
ely taken place?
tx tx
a. in Cindy's gametes
tx tx
b. in the cells that should normally have given rise to Cindy's tail
tx tx tx tx tx tx tx tx tx tx tx
c. in the cells that should normally have given rise to Cindy's and her puppies' tails
tx tx tx tx tx tx tx tx tx tx tx tx tx tx
d. in all of Cindy's cells (including her gametes)
tx tx tx tx tx tx tx
e. in a gamete of one of Cindy's parents
tx tx tx tx tx tx tx
ANSWER: a t x
11. Which of the following features makes a species suitable as a model organism?
tx tx tx tx tx tx tx tx tx tx tx tx
2|Page
tx tx tx tx
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