Wyoming - Multistate Pharmacy Jurisprudence
Examination (MPJE) Questions and Correct
Answers (Verified Answers) Plus Rationales
2026/2027 / Q&A Instant Download Pdf
1. Which federal law establishes the requirement for prescription drugs to be dispensed only by a
licensed practitioner?
A) Pure Food and Drug Act
B) *Food, Drug, and Cosmetic Act (FDCA)
C) Harrison Narcotics Tax Act
D) Durham-Humphrey Amendment
Answer: D
Rationale: The Durham-Humphrey Amendment (1951) distinguished prescription drugs from OTC drugs
and required dispensing by prescription.
2. Under the Controlled Substances Act, which schedule has the highest abuse potential?
A) Schedule V
B) Schedule IV
C) *Schedule II
D) Schedule I
Answer: D
Rationale: Schedule I drugs have no accepted medical use and the highest abuse potential (e.g., heroin,
LSD).
3. Wyoming pharmacists must complete how many hours of continuing education per renewal
cycle?
A) 10 hours
,B) *15 hours
C) 20 hours
D) 30 hours
Answer: B
Rationale: Wyoming requires 15 hours of CE per 2-year renewal cycle, including 1 hour of opioid/pain
management.
4. Which of the following is required for a valid Schedule II prescription in Wyoming?
A) Oral order only
B) *Written or electronic prescription, signed by the prescriber
C) Refill authorization for 6 months
D) No DEA number required
Answer: B
Rationale: Schedule II prescriptions must be written or electronic, manually signed, and cannot be
refilled.
5. A Wyoming pharmacist may administer immunizations to patients aged:
A) 18 years and older
B) *According to a prescriber's protocol, including children
C) Only adults over 65
D) Only with a physician present
Answer: B
Rationale: Wyoming pharmacists can administer vaccines per protocol; age depends on specific vaccine
and training.
6. The Wyoming PDMP (Prescription Drug Monitoring Program) requires dispensers to report
controlled substance dispensing within:
A) 7 days
,B) *24 hours
C) 72 hours
D) Monthly
Answer: B
Rationale: Wyoming requires reporting to the PDMP within 24 hours of dispensing controlled
substances.
7. Which DEA form is used to order Schedule II controlled substances?
A) DEA Form 106
B) *DEA Form 222
C) DEA Form 224
D) DEA Form 363
Answer: B
Rationale: DEA Form 222 (or CSOS electronic equivalent) is used to order Schedule II drugs.
8. A pharmacist in Wyoming may dispense a 90-day supply of a Schedule II medication:
A) True
B) *False
C) Only with physician approval
D) Only for hospice patients
Answer: B
Rationale: Schedule II prescriptions cannot be refilled; a new prescription is required for each dispensing.
9. Which of the following is a Schedule III controlled substance?
A) Oxycodone
B) *Testosterone
C) Alprazolam
D) Heroin
, Answer: B
Rationale: Testosterone is Schedule III; oxycodone is Schedule II, alprazolam is Schedule IV, heroin is
Schedule I.
10. Wyoming pharmacy technicians must be registered with:
A) The DEA
B) *The Wyoming Board of Pharmacy
C) The FDA
D) The state nursing board
Answer: B
Rationale: Pharmacy technicians must register with the Wyoming Board of Pharmacy.
11. A prescription for a Schedule II drug may be transmitted orally in an emergency if:
A) The pharmacist approves
B) *The quantity is limited to the emergency period, and a written prescription follows within 7 days
C) The patient signs a waiver
D) It is for a hospice patient
Answer: B
Rationale: Emergency oral Schedule II prescriptions require follow-up written prescription within 7 days.
12. Wyoming law requires that prescription labels include:
A) Only the patient's name
B) *Patient name, drug name, directions, date, prescriber, and pharmacy information
C) Only the drug name
D) The pharmacist's home address
Answer: B
Rationale: Wyoming requires complete labeling per federal and state law.
Examination (MPJE) Questions and Correct
Answers (Verified Answers) Plus Rationales
2026/2027 / Q&A Instant Download Pdf
1. Which federal law establishes the requirement for prescription drugs to be dispensed only by a
licensed practitioner?
A) Pure Food and Drug Act
B) *Food, Drug, and Cosmetic Act (FDCA)
C) Harrison Narcotics Tax Act
D) Durham-Humphrey Amendment
Answer: D
Rationale: The Durham-Humphrey Amendment (1951) distinguished prescription drugs from OTC drugs
and required dispensing by prescription.
2. Under the Controlled Substances Act, which schedule has the highest abuse potential?
A) Schedule V
B) Schedule IV
C) *Schedule II
D) Schedule I
Answer: D
Rationale: Schedule I drugs have no accepted medical use and the highest abuse potential (e.g., heroin,
LSD).
3. Wyoming pharmacists must complete how many hours of continuing education per renewal
cycle?
A) 10 hours
,B) *15 hours
C) 20 hours
D) 30 hours
Answer: B
Rationale: Wyoming requires 15 hours of CE per 2-year renewal cycle, including 1 hour of opioid/pain
management.
4. Which of the following is required for a valid Schedule II prescription in Wyoming?
A) Oral order only
B) *Written or electronic prescription, signed by the prescriber
C) Refill authorization for 6 months
D) No DEA number required
Answer: B
Rationale: Schedule II prescriptions must be written or electronic, manually signed, and cannot be
refilled.
5. A Wyoming pharmacist may administer immunizations to patients aged:
A) 18 years and older
B) *According to a prescriber's protocol, including children
C) Only adults over 65
D) Only with a physician present
Answer: B
Rationale: Wyoming pharmacists can administer vaccines per protocol; age depends on specific vaccine
and training.
6. The Wyoming PDMP (Prescription Drug Monitoring Program) requires dispensers to report
controlled substance dispensing within:
A) 7 days
,B) *24 hours
C) 72 hours
D) Monthly
Answer: B
Rationale: Wyoming requires reporting to the PDMP within 24 hours of dispensing controlled
substances.
7. Which DEA form is used to order Schedule II controlled substances?
A) DEA Form 106
B) *DEA Form 222
C) DEA Form 224
D) DEA Form 363
Answer: B
Rationale: DEA Form 222 (or CSOS electronic equivalent) is used to order Schedule II drugs.
8. A pharmacist in Wyoming may dispense a 90-day supply of a Schedule II medication:
A) True
B) *False
C) Only with physician approval
D) Only for hospice patients
Answer: B
Rationale: Schedule II prescriptions cannot be refilled; a new prescription is required for each dispensing.
9. Which of the following is a Schedule III controlled substance?
A) Oxycodone
B) *Testosterone
C) Alprazolam
D) Heroin
, Answer: B
Rationale: Testosterone is Schedule III; oxycodone is Schedule II, alprazolam is Schedule IV, heroin is
Schedule I.
10. Wyoming pharmacy technicians must be registered with:
A) The DEA
B) *The Wyoming Board of Pharmacy
C) The FDA
D) The state nursing board
Answer: B
Rationale: Pharmacy technicians must register with the Wyoming Board of Pharmacy.
11. A prescription for a Schedule II drug may be transmitted orally in an emergency if:
A) The pharmacist approves
B) *The quantity is limited to the emergency period, and a written prescription follows within 7 days
C) The patient signs a waiver
D) It is for a hospice patient
Answer: B
Rationale: Emergency oral Schedule II prescriptions require follow-up written prescription within 7 days.
12. Wyoming law requires that prescription labels include:
A) Only the patient's name
B) *Patient name, drug name, directions, date, prescriber, and pharmacy information
C) Only the drug name
D) The pharmacist's home address
Answer: B
Rationale: Wyoming requires complete labeling per federal and state law.
