NR 605: DIAGNOSIS AND
MANAGEMENT IN PSYCHIATRIC-
MENTAL HEALTH ACROSS THE
LIFESPAN COMPREHENSIVE EXAM
QUESTIONS & ANSWERS
(CHAMBERLAIN) 100% GUARANTEE
PASS
1. Which neurotransmitter is primarily implicated in the regulation of mood, sleep, and
appetite, and is the target of most first-line antidepressant treatments?
A. Dopamine
B. Serotonin
C. Norepinephrine
D. GABA
Answer: B
Conceptual Explanation: Serotonin (5-HT) plays a key role in mood, sleep, and appetite
regulation. SSRIs, which increase serotonin levels in the synaptic cleft, are the first-line
treatment for depression.
,2. A patient presents with a history of at least one hypomanic episode and at least one major
depressive episode. What is the most likely DSM-5-TR diagnosis?
A. Bipolar I Disorder
B. Bipolar II Disorder
C. Cyclothymic Disorder
D. Major Depressive Disorder
Answer: B
Conceptual Explanation: Bipolar II Disorder is characterized by at least one hypomanic
episode and at least one major depressive episode, without any full manic episodes.
3. What is the primary mechanism of action for second-generation (atypical) antipsychotics
that distinguishes them from first-generation (typical) antipsychotics?
A. D2 receptor antagonism only
B. Alpha-1 adrenergic blockade
C. NMDA receptor agonism
D. Serotonin-dopamine antagonism (5-HT2A and D2)
Answer: D
Conceptual Explanation: Atypical antipsychotics block both D2 receptors and 5-HT2A
serotonin receptors, which helps mitigate extrapyramidal symptoms and improve negative
symptoms of schizophrenia.
, 4. Lithium toxicity is a medical emergency. Which of the following serum levels indicates
severe toxicity requiring immediate intervention such as hemodialysis?
A. 2.5 mEq/L
B. 1.2 mEq/L
C. 1.5 mEq/L
D. 0.8 mEq/L
Answer: A
Conceptual Explanation: Serum lithium levels above 2.0-2.5 mEq/L are considered
severely toxic and typically require urgent medical intervention like hemodialysis.
5. Which brain region is most closely associated with the ‘fear circuit’ and the
pathophysiology of anxiety disorders and PTSD?
A. Prefrontal cortex
B. Amygdala
C. Hippocampus
D. Basal ganglia
Answer: B
Conceptual Explanation: The amygdala is the center for emotional processing,
particularly fear and aggression, and is often overactive in individuals with anxiety and
PTSD.
MANAGEMENT IN PSYCHIATRIC-
MENTAL HEALTH ACROSS THE
LIFESPAN COMPREHENSIVE EXAM
QUESTIONS & ANSWERS
(CHAMBERLAIN) 100% GUARANTEE
PASS
1. Which neurotransmitter is primarily implicated in the regulation of mood, sleep, and
appetite, and is the target of most first-line antidepressant treatments?
A. Dopamine
B. Serotonin
C. Norepinephrine
D. GABA
Answer: B
Conceptual Explanation: Serotonin (5-HT) plays a key role in mood, sleep, and appetite
regulation. SSRIs, which increase serotonin levels in the synaptic cleft, are the first-line
treatment for depression.
,2. A patient presents with a history of at least one hypomanic episode and at least one major
depressive episode. What is the most likely DSM-5-TR diagnosis?
A. Bipolar I Disorder
B. Bipolar II Disorder
C. Cyclothymic Disorder
D. Major Depressive Disorder
Answer: B
Conceptual Explanation: Bipolar II Disorder is characterized by at least one hypomanic
episode and at least one major depressive episode, without any full manic episodes.
3. What is the primary mechanism of action for second-generation (atypical) antipsychotics
that distinguishes them from first-generation (typical) antipsychotics?
A. D2 receptor antagonism only
B. Alpha-1 adrenergic blockade
C. NMDA receptor agonism
D. Serotonin-dopamine antagonism (5-HT2A and D2)
Answer: D
Conceptual Explanation: Atypical antipsychotics block both D2 receptors and 5-HT2A
serotonin receptors, which helps mitigate extrapyramidal symptoms and improve negative
symptoms of schizophrenia.
, 4. Lithium toxicity is a medical emergency. Which of the following serum levels indicates
severe toxicity requiring immediate intervention such as hemodialysis?
A. 2.5 mEq/L
B. 1.2 mEq/L
C. 1.5 mEq/L
D. 0.8 mEq/L
Answer: A
Conceptual Explanation: Serum lithium levels above 2.0-2.5 mEq/L are considered
severely toxic and typically require urgent medical intervention like hemodialysis.
5. Which brain region is most closely associated with the ‘fear circuit’ and the
pathophysiology of anxiety disorders and PTSD?
A. Prefrontal cortex
B. Amygdala
C. Hippocampus
D. Basal ganglia
Answer: B
Conceptual Explanation: The amygdala is the center for emotional processing,
particularly fear and aggression, and is often overactive in individuals with anxiety and
PTSD.
