NURS 5463 TEST 4 PRACTICE TEST BANK
SOLVED QUESTIONS WITH FULL SOLUTION
AND DETAILED ANSWERS GRADED A+
⩥ What are the risks associated with Acyclovir?
Answer: Nephrotoxicity (crystal nephropathy) and neurotoxicity.
⩥ What is essential to ensure when administering Acyclovir?
Answer: Ensure adequate hydration and dose-adjust in renal impairment.
⩥ What common infections are associated with Candida albicans?
Answer: Oral thrush, vaginitis, and candidemia.
⩥ What risk factors are associated with Candida glabrata/krusei?
Answer: ICU admission, central lines, and neutropenia.
⩥ What infections are caused by Aspergillus fumigatus?
Answer: Pulmonary aspergillosis and invasive disease.
⩥ What are the risk factors for Cryptococcus neoformans infections?
Answer: HIV/AIDS and transplant patients.
,⩥ What common infection is associated with Histoplasma capsulatum?
Answer: Pulmonary disease, especially in the Midwest USA.
⩥ What exposure risks are associated with Blastomyces dermatitidis?
Answer: Exposure to the Ohio/Mississippi river valley.
⩥ What is the clinical indication for Azoles?
Answer: Used for oral candidiasis, esophagitis, and aspergillosis.
⩥ What are the examples of Echinocandins and their clinical use?
Answer: Examples include Micafungin and Caspofungin, used for
invasive candidiasis and neutropenic fever.
⩥ What is the primary use of Amphotericin B?
Answer: Reserved for severe systemic fungal infections due to its
toxicity.
⩥ What is the role of Flucytosine in antifungal therapy?
Answer: It is often used synergistically with Amphotericin B for
cryptococcal meningitis.
⩥ What are the key points for NP practice regarding antifungal therapy?
, Answer: Consider the patient's immune status and infection site;
Echinocandins are first line for candidemia; Voriconazole is first line for
invasive aspergillosis.
⩥ What is the typical duration for surgical prophylaxis antibiotics?
Answer: Typically 24-48 hours post-surgery unless an infection is
identified.
⩥ What should be considered when adjusting the duration of
postoperative antibiotics?
Answer: Adjust based on the patient's clinical response, infection
severity, and pathogen identified.
⩥ When are broad-spectrum antibiotics used?
Answer: Used empirically in severe infections where the pathogen is
unknown.
⩥ What are some examples of fluoroquinolones?
Answer: Ciprofloxacin, Levofloxacin, Moxifloxacin.
⩥ What are some examples of carbapenems?
Answer: Meropenem, Imipenem, Ertapenem.
SOLVED QUESTIONS WITH FULL SOLUTION
AND DETAILED ANSWERS GRADED A+
⩥ What are the risks associated with Acyclovir?
Answer: Nephrotoxicity (crystal nephropathy) and neurotoxicity.
⩥ What is essential to ensure when administering Acyclovir?
Answer: Ensure adequate hydration and dose-adjust in renal impairment.
⩥ What common infections are associated with Candida albicans?
Answer: Oral thrush, vaginitis, and candidemia.
⩥ What risk factors are associated with Candida glabrata/krusei?
Answer: ICU admission, central lines, and neutropenia.
⩥ What infections are caused by Aspergillus fumigatus?
Answer: Pulmonary aspergillosis and invasive disease.
⩥ What are the risk factors for Cryptococcus neoformans infections?
Answer: HIV/AIDS and transplant patients.
,⩥ What common infection is associated with Histoplasma capsulatum?
Answer: Pulmonary disease, especially in the Midwest USA.
⩥ What exposure risks are associated with Blastomyces dermatitidis?
Answer: Exposure to the Ohio/Mississippi river valley.
⩥ What is the clinical indication for Azoles?
Answer: Used for oral candidiasis, esophagitis, and aspergillosis.
⩥ What are the examples of Echinocandins and their clinical use?
Answer: Examples include Micafungin and Caspofungin, used for
invasive candidiasis and neutropenic fever.
⩥ What is the primary use of Amphotericin B?
Answer: Reserved for severe systemic fungal infections due to its
toxicity.
⩥ What is the role of Flucytosine in antifungal therapy?
Answer: It is often used synergistically with Amphotericin B for
cryptococcal meningitis.
⩥ What are the key points for NP practice regarding antifungal therapy?
, Answer: Consider the patient's immune status and infection site;
Echinocandins are first line for candidemia; Voriconazole is first line for
invasive aspergillosis.
⩥ What is the typical duration for surgical prophylaxis antibiotics?
Answer: Typically 24-48 hours post-surgery unless an infection is
identified.
⩥ What should be considered when adjusting the duration of
postoperative antibiotics?
Answer: Adjust based on the patient's clinical response, infection
severity, and pathogen identified.
⩥ When are broad-spectrum antibiotics used?
Answer: Used empirically in severe infections where the pathogen is
unknown.
⩥ What are some examples of fluoroquinolones?
Answer: Ciprofloxacin, Levofloxacin, Moxifloxacin.
⩥ What are some examples of carbapenems?
Answer: Meropenem, Imipenem, Ertapenem.
