BANK | HIGH-YIELD PHARMACOLOGY PRACTICE QUESTIONS & STUDY
GUIDE | VERIFIED ANSWERS | LATEST UPDATE
1. A type II hypersensitivity reaction occurs when a normal constituent is viewed
as foreign by the body. An example of a type II reaction is:
Rh-hemolytic disease (newborn).
bacterial endocarditis.
rheumatoid arthritis.
lupus erythematosus.
2. Infants and children are most at risk for complications related to the
administration of medications due to:
their immature neurological system
their small size and immature renal system
family history of med use
their immature respiratory system
3. If a nurse is administering a beta-blocker to an older patient with decreased
renal function, what should be the nurse's primary consideration?
Increasing the dosage to ensure effectiveness
Administering the standard dose without changes
Monitoring for allergic reactions only
Adjusting the dosage based on renal function
4. What is one key factor that affects drug metabolism in older adults?
Renal function
, Skin thickness
Body temperature
Liver size
5. Describe the relationship between renal function and the pharmacokinetics
of medications.
Renal function affects the pharmacokinetics of medications by
altering their elimination rates, which can lead to drug accumulation
and toxicity.
Renal function has no impact on pharmacokinetics.
Renal function only affects drug absorption.
Renal function enhances drug efficacy.
6. What is a common adverse effect associated with beta-blockers?
Bradycardia
Hypertension
Hyperglycemia
Nausea
7. The main goal of which phase of drug development is to explore therapeutic
efficacy in patients? It is important during this phase to determine the dose
and regimens that will be used for later trials.
Phase 2
Phase 3
Phase 4
Phase 1
,8. Describe the significance of selecting the appropriate drug in the WHO
prescribing process.
Selecting the appropriate drug is the final step in the process.
Selecting the appropriate drug only considers the drug's cost.
Selecting the appropriate drug ensures that the treatment is
effective and safe for the patient.
Selecting the appropriate drug is less important than assessing the
patient's condition.
9. What specific patient factors should be considered when prescribing
medication to infants and children?
Age and renal function
Family medical history
Diet and exercise
Weight and height
10. What factors contribute to the slower absorption rates of oral, intramuscular,
and subcutaneous drug administration routes?
The presence of barriers such as the gastrointestinal tract for oral,
and the need for diffusion through tissue for IM and SQ.
The rapid metabolism of drugs in the liver for oral administration.
The use of intravenous administration which bypasses absorption.
The immediate entry of drugs into the bloodstream for all routes.
11. Describe how beta-blockers affect cardiovascular function.
, Beta-blockers decrease heart rate and contractility, leading to
lower blood pressure and reduced cardiac workload.
Beta-blockers have no significant effect on cardiovascular function.
Beta-blockers primarily affect respiratory function by dilating airways.
Beta-blockers increase heart rate and blood flow, enhancing oxygen
delivery to tissues.
12. A patient with chronic kidney disease is prescribed a medication that is
primarily eliminated by the kidneys. What should the nurse do to ensure safe
medication administration?
Increase the dosage to enhance effectiveness.
Administer the standard dosage without modification.
Adjust the medication dosage based on the patient's renal function.
Switch to an oral form of the medication.
13. A patient presents with hemolytic anemia following a blood transfusion.
Which type of hypersensitivity reaction is likely involved, and what is the
underlying cause?
Type 3 hypersensitivity due to immune complex deposition.
Type 2 hypersensitivity due to antibody-mediated destruction of
red blood cells.
Type 1 hypersensitivity due to IgE-mediated mast cell degranulation.
Type 4 hypersensitivity due to T-cell mediated response.
14. In a clinical scenario, a patient with both hypertension and heart failure is
prescribed carvedilol. What should the nurse monitor closely due to
carvedilol's unique pharmacological profile?