APEA COMPREHENSIVE TEST QUESTIONS AND SOLUTIONS
● The ophthalmic preparation that is NOT available OTC is:
Answer:Hydroxypropyl cellulose (Lacrisert), a lubricant
● Oseltamivir (Tamiflu) is an antiviral agent, further classified as a(n):
Answer:Neuraminidase inhibitor
● The duration of action of ocular decongestants such as oxymetazoline
(Visine-LR) is approximately: Answer:6 hours-pts should be advised to
apply 1-2 drops in the affected eye q 6 hours
● The mechanism of action for macrolides is to: Answer:block the
dissociation of peptidyl tRNA from ribosomes
● 2nd generation antihistamines: Answer:have a variety of anti-
inflammatory properties-including decreased mast cell mediator
properties and downregulation of adhesion molecule expression
,● After the administration of olopatadine (Pataday) ophthalmic for
allergic conjunctivitis, contact lenses should not be inserted for at least:
Answer:10 minutes-do not insert if eyes are red
● Which of the following is NOT a mechanism of action of ocular
steroids? Answer:Promotes capillary proliferation and dilation
● The mechanism of action of polymyxin B/trimethoprim ophthalmic is:
Answer:Increased cell wall permeability/inhibition of nucleic acid and
protein synthesis
● Sulfacetamide/prednisolone (Blephamide) is NOT indicated in:
Answer:Ocular mycobacterial infection (ocular tuberculosis)
● The mechanism of action of pheniramine is that it:
Answer:Antagonized histamine-1 receptors
● The duration of action of meclizine (Antivert) is: Answer:8 hours-1st
gen antihistamine , onset ~1 hr with half-life of 6 hours
● The mechanism of action for mast cell stabilizers is: Answer:Inhibition
of histamine release and slow reacting substances of anaphylaxis
● The brand name for sulfacetamide ophthalmic is: Answer:Bleph-10
, ● The vasoconstrictive properties of alpha- agonist medications make
them beneficial for the tx of: Answer:Sinus congestion-used to reduce
edema and inflammation within sinus cavities
● The generic name for Dramamine is: Answer:Dimehydrinate
● Which risk factor would NOT prohibit the NP from prescribing
prednisolone acetate (Pred Forte)? Answer:Superficial punctate keratitis
● Which of the following organisms is NOT susceptible to
sulfacetamide ophthalmic (Bleph-10)? Answer:Psuedomonas
aeruginosa- does not provide adequate coverage against Neisseria
species
● A medication that acts on the hypothalamus to produce antipyresis is:
Answer:Acetaminophen
● Azelasine (Astelin), for tx of allergic rhinitis, is classified as a nasal:
Answer:Antihistamine
● A serious adverse reaction to clindamycin (Cleocin) is:
Answer:Clostridium difficile-related colitis
● The ophthalmic preparation that is NOT available OTC is:
Answer:Hydroxypropyl cellulose (Lacrisert), a lubricant
● Oseltamivir (Tamiflu) is an antiviral agent, further classified as a(n):
Answer:Neuraminidase inhibitor
● The duration of action of ocular decongestants such as oxymetazoline
(Visine-LR) is approximately: Answer:6 hours-pts should be advised to
apply 1-2 drops in the affected eye q 6 hours
● The mechanism of action for macrolides is to: Answer:block the
dissociation of peptidyl tRNA from ribosomes
● 2nd generation antihistamines: Answer:have a variety of anti-
inflammatory properties-including decreased mast cell mediator
properties and downregulation of adhesion molecule expression
,● After the administration of olopatadine (Pataday) ophthalmic for
allergic conjunctivitis, contact lenses should not be inserted for at least:
Answer:10 minutes-do not insert if eyes are red
● Which of the following is NOT a mechanism of action of ocular
steroids? Answer:Promotes capillary proliferation and dilation
● The mechanism of action of polymyxin B/trimethoprim ophthalmic is:
Answer:Increased cell wall permeability/inhibition of nucleic acid and
protein synthesis
● Sulfacetamide/prednisolone (Blephamide) is NOT indicated in:
Answer:Ocular mycobacterial infection (ocular tuberculosis)
● The mechanism of action of pheniramine is that it:
Answer:Antagonized histamine-1 receptors
● The duration of action of meclizine (Antivert) is: Answer:8 hours-1st
gen antihistamine , onset ~1 hr with half-life of 6 hours
● The mechanism of action for mast cell stabilizers is: Answer:Inhibition
of histamine release and slow reacting substances of anaphylaxis
● The brand name for sulfacetamide ophthalmic is: Answer:Bleph-10
, ● The vasoconstrictive properties of alpha- agonist medications make
them beneficial for the tx of: Answer:Sinus congestion-used to reduce
edema and inflammation within sinus cavities
● The generic name for Dramamine is: Answer:Dimehydrinate
● Which risk factor would NOT prohibit the NP from prescribing
prednisolone acetate (Pred Forte)? Answer:Superficial punctate keratitis
● Which of the following organisms is NOT susceptible to
sulfacetamide ophthalmic (Bleph-10)? Answer:Psuedomonas
aeruginosa- does not provide adequate coverage against Neisseria
species
● A medication that acts on the hypothalamus to produce antipyresis is:
Answer:Acetaminophen
● Azelasine (Astelin), for tx of allergic rhinitis, is classified as a nasal:
Answer:Antihistamine
● A serious adverse reaction to clindamycin (Cleocin) is:
Answer:Clostridium difficile-related colitis
