MSN 570 Week 5 Quiz | Questions and
Answers | 2026/27 Update | 100% Correct -
USU.
MSN 570 Week 5 Quiz
100 Practice Questions with Answers & Rationales | 2026/27 Update | United
States University
Number of Questions: 100
Time Allowed: 120 minutes
Format: Multiple choice (single best answer)
Answer Key & Rationales: Provided after each question
SECTION 1: INFLAMMATION & IMMUNITY
1. What is the vascular effect of histamine released from mast cells?
A) Vasoconstriction
B) Vasodilation and increased capillary permeability
C) Decreased blood flow
D) Reduced immune cell recruitment
Answer: B. Vasodilation and increased capillary permeability
Rationale: Histamine released from mast cells causes vasodilation, which
increases local blood flow and capillary permeability. This is a fundamental
component of the acute inflammatory response, allowing immune cells and
plasma proteins to reach the site of injury or infection .
,2. Which action is a purpose of the inflammatory process?
A) To provide specific responses toward antigens
B) To lyse cell membranes of microorganisms
C) To prevent infection of the injured tissue
D) To create immunity against subsequent tissue injury
Answer: C. To prevent infection of the injured tissue
Rationale: The inflammatory process serves to prevent infection of injured tissue.
This innate immune response is rapid and non-specific, providing immediate
defense while the adaptive immune system mounts a more specific response .
3. Which of the following is an effect of cytokines?
A) Activate and stimulate proliferation of B and T lymphocytes
B) Destroy antigens quickly
C) Increase the rate of mitosis in tumors
D) Cause immediate pain
Answer: A. Activate and stimulate proliferation of B and T lymphocytes
Rationale: Cytokines are signaling molecules that regulate immune responses.
They activate and stimulate the proliferation of B and T lymphocytes .
4. What does seroconversion mean in relation to HIV and AIDS?
A) The virus has been identified in the blood and body fluids
B) Antibodies for HIV have been identified in the blood
C) HIV was found in lymphocytes
D) Active infection has developed in the patient
Answer: B. Antibodies for HIV have been identified in the blood
Rationale: Seroconversion refers to the development of detectable antibodies
against HIV in the blood. This typically occurs 2-4 weeks after exposure .
,5. HIV results in which of the following?
A) Decrease in the CD4+ cell population
B) Increase in the CD4+ cell population
C) Decrease in the CD8+ cell population
D) Increase in natural killer cells
Answer: A. Decrease in the CD4+ cell population
Rationale: HIV infection results in progressive depletion of CD4+ T lymphocytes.
The virus binds to CD4 receptors, enters cells, and replicates, ultimately destroying
them .
6. Which statement concerning exotoxins is true?
A) Exotoxins are contained in cell walls of gram-negative bacteria
B) Exotoxins are released during the lysis of bacteria
C) Exotoxins are able to initiate the complement and coagulation cascades
D) Exotoxins are released during bacterial growth
Answer: D. Exotoxins are released during bacterial growth
Rationale: Exotoxins are proteins released during bacterial growth. Endotoxins are
contained in cell walls of gram-negative bacteria .
7. Which histologic finding in an affected area would suggest chronic
inflammation?
A) Predominance of neutrophils
B) Absence of fibroblasts and proteases
C) Decrease in degradation products
D) Increase in monocytes and macrophages
Answer: D. Increase in monocytes and macrophages
, Rationale: Chronic inflammation is characterized by infiltration of mononuclear
cells, including monocytes, macrophages, and lymphocytes. Neutrophils are
predominant in acute inflammation .
8. Atopic dermatitis often occurs along with which condition?
A) Asthma
B) Hypertension
C) Acne
D) Diabetes mellitus
Answer: A. Asthma
Rationale: Atopic dermatitis commonly occurs along with asthma, allergic rhinitis,
and food allergies, reflecting the atopic triad .
9. Hypersensitivity is best defined as:
A) Disturbance in the immunologic tolerance of self-antigens
B) Immunologic reaction of one person to the tissue of another person
C) Altered immunologic response to an antigen that results in disease
D) Undetectable immune response in the presence of antigens
Answer: C. Altered immunologic response to an antigen that results in disease
Rationale: Hypersensitivity is an altered immunologic response to an antigen that
results in disease or damage to the host .
10. Which type of antibody is involved in type I hypersensitivity reaction?
A) IgA
B) IgG
C) IgM
D) IgE
Answers | 2026/27 Update | 100% Correct -
USU.
MSN 570 Week 5 Quiz
100 Practice Questions with Answers & Rationales | 2026/27 Update | United
States University
Number of Questions: 100
Time Allowed: 120 minutes
Format: Multiple choice (single best answer)
Answer Key & Rationales: Provided after each question
SECTION 1: INFLAMMATION & IMMUNITY
1. What is the vascular effect of histamine released from mast cells?
A) Vasoconstriction
B) Vasodilation and increased capillary permeability
C) Decreased blood flow
D) Reduced immune cell recruitment
Answer: B. Vasodilation and increased capillary permeability
Rationale: Histamine released from mast cells causes vasodilation, which
increases local blood flow and capillary permeability. This is a fundamental
component of the acute inflammatory response, allowing immune cells and
plasma proteins to reach the site of injury or infection .
,2. Which action is a purpose of the inflammatory process?
A) To provide specific responses toward antigens
B) To lyse cell membranes of microorganisms
C) To prevent infection of the injured tissue
D) To create immunity against subsequent tissue injury
Answer: C. To prevent infection of the injured tissue
Rationale: The inflammatory process serves to prevent infection of injured tissue.
This innate immune response is rapid and non-specific, providing immediate
defense while the adaptive immune system mounts a more specific response .
3. Which of the following is an effect of cytokines?
A) Activate and stimulate proliferation of B and T lymphocytes
B) Destroy antigens quickly
C) Increase the rate of mitosis in tumors
D) Cause immediate pain
Answer: A. Activate and stimulate proliferation of B and T lymphocytes
Rationale: Cytokines are signaling molecules that regulate immune responses.
They activate and stimulate the proliferation of B and T lymphocytes .
4. What does seroconversion mean in relation to HIV and AIDS?
A) The virus has been identified in the blood and body fluids
B) Antibodies for HIV have been identified in the blood
C) HIV was found in lymphocytes
D) Active infection has developed in the patient
Answer: B. Antibodies for HIV have been identified in the blood
Rationale: Seroconversion refers to the development of detectable antibodies
against HIV in the blood. This typically occurs 2-4 weeks after exposure .
,5. HIV results in which of the following?
A) Decrease in the CD4+ cell population
B) Increase in the CD4+ cell population
C) Decrease in the CD8+ cell population
D) Increase in natural killer cells
Answer: A. Decrease in the CD4+ cell population
Rationale: HIV infection results in progressive depletion of CD4+ T lymphocytes.
The virus binds to CD4 receptors, enters cells, and replicates, ultimately destroying
them .
6. Which statement concerning exotoxins is true?
A) Exotoxins are contained in cell walls of gram-negative bacteria
B) Exotoxins are released during the lysis of bacteria
C) Exotoxins are able to initiate the complement and coagulation cascades
D) Exotoxins are released during bacterial growth
Answer: D. Exotoxins are released during bacterial growth
Rationale: Exotoxins are proteins released during bacterial growth. Endotoxins are
contained in cell walls of gram-negative bacteria .
7. Which histologic finding in an affected area would suggest chronic
inflammation?
A) Predominance of neutrophils
B) Absence of fibroblasts and proteases
C) Decrease in degradation products
D) Increase in monocytes and macrophages
Answer: D. Increase in monocytes and macrophages
, Rationale: Chronic inflammation is characterized by infiltration of mononuclear
cells, including monocytes, macrophages, and lymphocytes. Neutrophils are
predominant in acute inflammation .
8. Atopic dermatitis often occurs along with which condition?
A) Asthma
B) Hypertension
C) Acne
D) Diabetes mellitus
Answer: A. Asthma
Rationale: Atopic dermatitis commonly occurs along with asthma, allergic rhinitis,
and food allergies, reflecting the atopic triad .
9. Hypersensitivity is best defined as:
A) Disturbance in the immunologic tolerance of self-antigens
B) Immunologic reaction of one person to the tissue of another person
C) Altered immunologic response to an antigen that results in disease
D) Undetectable immune response in the presence of antigens
Answer: C. Altered immunologic response to an antigen that results in disease
Rationale: Hypersensitivity is an altered immunologic response to an antigen that
results in disease or damage to the host .
10. Which type of antibody is involved in type I hypersensitivity reaction?
A) IgA
B) IgG
C) IgM
D) IgE
