ANCC Medical-Surgical Nursing Certification (MEDSURG-
BC™) Comprehensive Practice Examination: 250 Color-
Coded Questions with Verified Answers and Detailed
Rationales Covering Cardiovascular, Respiratory,
Neurological, Gastrointestinal, Renal, Endocrine,
Musculoskeletal, Hematologic, and Professional Role
Content Domains for 2026–2027 Exam Preparation
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ANCC MEDICAL-SURGICAL NURSING CERTIFICATION
(MEDSURG-BC™) PRACTICE EXAMINATION
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DOCUMENT TITLE:
ANCC Medical-Surgical Nursing Certification (MEDSURG-BC™) Comprehensive
Practice Examination: 250 Color-Coded Questions with Verified Answers and
Detailed Rationales Across Nine Clinical and Professional Domains for
2025–2026 Board Certification Preparation
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EXAM OVERVIEW
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Total Questions ............ 250
Format ..................... Multiple-Choice, Select-All-That-Apply,
True/False, and Scenario-Based Questions
Time Allowed ............... 4 Hours (240 Minutes)
Recommended Passing Score .. 70% or Higher (Practice Benchmark)
Version .................... 2025–2026 Edition
Answer Format .............. Color-Coded (Blue Question / Red Answer /
Purple Rationale)
pg. 1
, ANCC MEDSURG-BC™ EXAM
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CONTENT DOMAINS COVERED
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1. Cardiovascular System ...................... 35 Questions (Q1–Q35)
2. Respiratory System ......................... 30 Questions (Q36–Q65)
3. Neurological System ........................ 30 Questions (Q66–Q95)
4. Gastrointestinal System .................... 30 Questions (Q96–Q125)
5. Renal and Genitourinary System ............. 30 Questions (Q126–Q155)
6. Endocrine System ........................... 30 Questions (Q156–Q185)
7. Musculoskeletal System ..................... 20 Questions (Q186–Q205)
8. Hematologic and Immune Systems ............. 20 Questions (Q206–Q225)
9. Professional Role and Ethical Considerations 25 Questions (Q226–Q250)
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ANCC EXAM BLUEPRINT ALIGNMENT
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Assessment and Diagnosis ...................... 39%
Planning, Implementation, and Evaluation ...... 40%
Professional Role .............................. 21%
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INSTRUCTIONS TO THE EXAMINEE
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1. Read each question carefully before selecting your answer.
2. For multiple-choice items, choose the SINGLE best answer.
3. For select-all-that-apply items, choose ALL answers that apply.
4. For true/false items, select the correct statement.
5. For scenario-based items, apply clinical judgment and evidence-based
practice guidelines.
6. Do NOT view the answer or rationale until you have selected your response.
7. Record your answers on a separate answer sheet for self-scoring.
pg. 2
, ANCC MEDSURG-BC™ EXAM
8. Review all rationales thoroughly, including explanations for why
incorrect options are wrong.
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COLOR-CODE KEY
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[BLUE] QUESTION — The exam question and answer options
[RED] ANSWER — The correct answer with letter and full text
[PURPLE] RATIONALE — Detailed explanation of the correct answer and why
other options are incorrect
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PREPARATION NOTES
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This practice examination is designed to simulate the format, difficulty,
and content coverage of the ANCC Medical-Surgical Nursing Certification
(MEDSURG-BC™) examination. All questions are aligned with current
evidence-based practice standards and the newest ANCC test blueprint.
This document is intended for educational and exam-preparation purposes
only and does not replace official ANCC study materials or clinical
judgment in practice.
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DOCUMENT INFORMATION
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Prepared For ....... Registered Nurses Preparing for MEDSURG-BC™ Certification
Content Review ..... Evidence-Based Practice and ANCC Test Blueprint
Publication Year ... 2026–2027
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BEGIN EXAMINATION
pg. 3
, ANCC MEDSURG-BC™ EXAM
ANCC MEDSURG-BC™ CERTIFICATION EXAMINATION
Comprehensive Practice Test – 250 Questions
Exam Overview:
• Total Questions: 250
• Content Domains: Assessment and Diagnosis (39%), Planning, Implementation, and
Evaluation (40%), Professional Role (21%)
• Format: Multiple-choice, select-all-that-apply, true/false, and scenario-based questions
• Time Allowed: 4 hours (simulating extended practice)
SECTION 1: CARDIOVASCULAR SYSTEM (Questions 1-35)
QUESTION 1:
A patient with acute decompensated heart failure is admitted with dyspnea, bilateral crackles, and
an oxygen saturation of 86% on room air. Which nursing intervention should be implemented FIRST?
A. Administer IV furosemide 40 mg as prescribed
B. Position the patient in high Fowler's position and apply supplemental oxygen
C. Obtain a 12-lead ECG
D. Insert an indwelling urinary catheter
ANSWER:
B. Position the patient in high Fowler's position and apply supplemental oxygen
RATIONALE:
The priority in acute decompensated heart failure with hypoxemia is to improve oxygenation and
breathing (ABC priority). High Fowler's position reduces venous return and pulmonary congestion,
while supplemental oxygen addresses the hypoxemia. While diuretics are essential, positioning and
oxygenation take immediate precedence. ECG and urinary catheter insertion are important but not
immediate life-saving interventions.
QUESTION 2:
A patient receiving a heparin infusion for acute coronary syndrome has an aPTT of 95 seconds. The
therapeutic range is 60-80 seconds. Which action should the nurse take?
A. Continue the current infusion rate and recheck in 6 hours
B. Stop the heparin infusion and notify the healthcare provider
C. Administer vitamin K 10 mg IV
D. Increase the infusion rate to maintain therapeutic levels
pg. 4