,Table of Contents
Chapter 01 Introduction to Pathophysiology 1
Chapter 02 Altered Cells and Tissues 9
Chapter 03 Inflammation and Tissue Inflammation and Tissue 18
Chapter 04 Altered Immunity 29
Chapter 05 Infection 39
Chapter 06 Genetic and Developmental Disorders 50
Chapter 07 Altered Cellular Proliferation and Differentiation 58
Chapter 08 Altered Fluid and Electrolyte Balance 66
Chapter 09 Altered Acid–Base Balance 74
Chapter 10 Altered Neural Function 82
Chapter 11 Altered Mood, Attention, and Behavior 94
Chapter 12 Altered Somatic and Special Sensory Function 102
Chapter 13 Altered Hormonal and Metabolic Regulation 115
Chapter 14 Altered Reproductive Function 123
Chapter 15 Altered Ventilation and Diffusion 133
Chapter 16 Altered Perfusion 141
Chapter 17 Altered Nutrition 154
Chapter 18 Altered Elimination 163
Chapter 19 Degenerative Changes in Aging 173
Chapter 20 Integrated Pathophysiologic Concepts 181
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Test Bank - Applied Pathophysiology: A Conceptual Approach, 4th Edition (Nath, 2023)
Chapter 1, Introduction to Pathophysiology
1. Which term is defined as the study of the mechanisms of human body functioning?
a. Pathology
b. Physiology
c. Anatomy
d. Pathophysiology
ANS: B
Feedback: Physiology is the study of the mechanisms of human body functioning.
Pathology is the study of changes in cells and tissues as a result of injury or disease.
Anatomy is the study of body structures. Pathophysiology is the study of mechanisms of
disease.
PTS: 1 REF: Page and Header: 2, Defining Pathophysiology
OBJ: 1
NAT: Client Needs: Physiological Integrity: Physiological Adaptation
TOP: Chapter: 1 KEY: Integrated Process: Teaching/Learning
BLM: Cognitive Level: Remember NOT: Multiple Choice
2. Which statement best describes the health–illness continuum?
a. It is a dynamic entity.
b. It is based on objective data.
c. It represents two exclusive categories.
d. It is focused on physical well-being.
ANS: A
Feedback: Health and illness are part of a dynamic continuum. It is based on one’s
perceptions and is subjective. There are a variety of descriptions one can use along the
continuum to describe their current state. These range from “extremely healthy” to
“extremely ill.” Because it is a dynamic continuum, it represents more than two exclusive
categories. The health–illness continuum includes the body, mind, and spirit, not just
physical well-being.
PTS: 1 REF: Page and Header: 4, Individual Health
OBJ: 1 NAT: Client Needs: Health Promotion and Maintenance
TOP: Chapter: 1 KEY: Integrated Process: Teaching/Learning
BLM: Cognitive Level: Remember NOT: Multiple Choice
3. Which concept is often equated with health?
a. Homeostasis
b. Disease
c. Objectivity
d. An uneventful physical examination
ANS: A
______________________________________________________________________________________________
1|Page
, ______________________________________________________________________________________________
Test Bank - Applied Pathophysiology: A Conceptual Approach, 4th Edition (Nath, 2023)
Feedback: Homeostasis is an important body goal and is often reflected in the client’s
perception of the health–illness continuum. Disease is the functional impairment of cells,
tissues, organs, or organ systems. Because health is reflected in the client’s perception of the
health–illness continuum, it is subjective, not objective. An uneventful physical examination
would only be on aspect of health. The health–illness continuum includes the body, mind,
and spirit.
PTS: 1 REF: Page and Header: 4, Individual Health
OBJ: 1 NAT: Client Needs: Health Promotion and Maintenance
TOP: Chapter: 1 KEY: Integrated Process: Teaching/Learning
BLM: Cognitive Level: Remember NOT: Multiple Choice
4. Which term is defined as the functional impairment of cells, tissues, organs, or organ
systems?
a. Injury
b. Pathophysiology
c. Disease
d. Syndrome
ANS: C
Feedback: Disease is defined as the functional impairment of cells, tissues, organs, or organ
systems. Injury causes changes to cells, pathophysiology refers to the study of mechanisms
of disease, and syndrome is used to describe specific conditions with predictive patterns.
PTS: 1 REF: Page and Header: 5, Population Health
OBJ: 1
NAT: Client Needs: Physiological Integrity: Physiological Adaptation
TOP: Chapter: 1 KEY: Integrated Process: Teaching/Learning
BLM: Cognitive Level: Remember NOT: Multiple Choice
5. The nurse is planning education on the importance of wearing a helmet when riding a bike.
What level of prevention is the nurse describing?
a. Primary
b. Secondary
c. Tertiary
d. Quaternary
ANS: A
Feedback: Primary prevention, such as wearing a bike helmet focuses on protecting people
from developing a disease or injury. Secondary prevention is the early detection of disease
through screening and early treatment. Tertiary prevention focuses on rehabilitation after
diagnosis of a disease or injury. Quaternary prevention relates to overmedicalization.
PTS: 1 REF: Page and Header: 5, Disease Prevention
OBJ: 4 NAT: Client Needs: Health Promotion and Maintenance
TOP: Chapter: 1 KEY: Integrated Process: Teaching/Learning
BLM: Cognitive Level: Apply NOT: Multiple Choice
6. A nurse in a rehabilitation unit is assisting a client who has had a stroke with relearning how
to perform activities of daily living. What level of prevention is the nurse implementing?
______________________________________________________________________________________________
2|Page
Chapter 01 Introduction to Pathophysiology 1
Chapter 02 Altered Cells and Tissues 9
Chapter 03 Inflammation and Tissue Inflammation and Tissue 18
Chapter 04 Altered Immunity 29
Chapter 05 Infection 39
Chapter 06 Genetic and Developmental Disorders 50
Chapter 07 Altered Cellular Proliferation and Differentiation 58
Chapter 08 Altered Fluid and Electrolyte Balance 66
Chapter 09 Altered Acid–Base Balance 74
Chapter 10 Altered Neural Function 82
Chapter 11 Altered Mood, Attention, and Behavior 94
Chapter 12 Altered Somatic and Special Sensory Function 102
Chapter 13 Altered Hormonal and Metabolic Regulation 115
Chapter 14 Altered Reproductive Function 123
Chapter 15 Altered Ventilation and Diffusion 133
Chapter 16 Altered Perfusion 141
Chapter 17 Altered Nutrition 154
Chapter 18 Altered Elimination 163
Chapter 19 Degenerative Changes in Aging 173
Chapter 20 Integrated Pathophysiologic Concepts 181
,______________________________________________________________________________________________
Test Bank - Applied Pathophysiology: A Conceptual Approach, 4th Edition (Nath, 2023)
Chapter 1, Introduction to Pathophysiology
1. Which term is defined as the study of the mechanisms of human body functioning?
a. Pathology
b. Physiology
c. Anatomy
d. Pathophysiology
ANS: B
Feedback: Physiology is the study of the mechanisms of human body functioning.
Pathology is the study of changes in cells and tissues as a result of injury or disease.
Anatomy is the study of body structures. Pathophysiology is the study of mechanisms of
disease.
PTS: 1 REF: Page and Header: 2, Defining Pathophysiology
OBJ: 1
NAT: Client Needs: Physiological Integrity: Physiological Adaptation
TOP: Chapter: 1 KEY: Integrated Process: Teaching/Learning
BLM: Cognitive Level: Remember NOT: Multiple Choice
2. Which statement best describes the health–illness continuum?
a. It is a dynamic entity.
b. It is based on objective data.
c. It represents two exclusive categories.
d. It is focused on physical well-being.
ANS: A
Feedback: Health and illness are part of a dynamic continuum. It is based on one’s
perceptions and is subjective. There are a variety of descriptions one can use along the
continuum to describe their current state. These range from “extremely healthy” to
“extremely ill.” Because it is a dynamic continuum, it represents more than two exclusive
categories. The health–illness continuum includes the body, mind, and spirit, not just
physical well-being.
PTS: 1 REF: Page and Header: 4, Individual Health
OBJ: 1 NAT: Client Needs: Health Promotion and Maintenance
TOP: Chapter: 1 KEY: Integrated Process: Teaching/Learning
BLM: Cognitive Level: Remember NOT: Multiple Choice
3. Which concept is often equated with health?
a. Homeostasis
b. Disease
c. Objectivity
d. An uneventful physical examination
ANS: A
______________________________________________________________________________________________
1|Page
, ______________________________________________________________________________________________
Test Bank - Applied Pathophysiology: A Conceptual Approach, 4th Edition (Nath, 2023)
Feedback: Homeostasis is an important body goal and is often reflected in the client’s
perception of the health–illness continuum. Disease is the functional impairment of cells,
tissues, organs, or organ systems. Because health is reflected in the client’s perception of the
health–illness continuum, it is subjective, not objective. An uneventful physical examination
would only be on aspect of health. The health–illness continuum includes the body, mind,
and spirit.
PTS: 1 REF: Page and Header: 4, Individual Health
OBJ: 1 NAT: Client Needs: Health Promotion and Maintenance
TOP: Chapter: 1 KEY: Integrated Process: Teaching/Learning
BLM: Cognitive Level: Remember NOT: Multiple Choice
4. Which term is defined as the functional impairment of cells, tissues, organs, or organ
systems?
a. Injury
b. Pathophysiology
c. Disease
d. Syndrome
ANS: C
Feedback: Disease is defined as the functional impairment of cells, tissues, organs, or organ
systems. Injury causes changes to cells, pathophysiology refers to the study of mechanisms
of disease, and syndrome is used to describe specific conditions with predictive patterns.
PTS: 1 REF: Page and Header: 5, Population Health
OBJ: 1
NAT: Client Needs: Physiological Integrity: Physiological Adaptation
TOP: Chapter: 1 KEY: Integrated Process: Teaching/Learning
BLM: Cognitive Level: Remember NOT: Multiple Choice
5. The nurse is planning education on the importance of wearing a helmet when riding a bike.
What level of prevention is the nurse describing?
a. Primary
b. Secondary
c. Tertiary
d. Quaternary
ANS: A
Feedback: Primary prevention, such as wearing a bike helmet focuses on protecting people
from developing a disease or injury. Secondary prevention is the early detection of disease
through screening and early treatment. Tertiary prevention focuses on rehabilitation after
diagnosis of a disease or injury. Quaternary prevention relates to overmedicalization.
PTS: 1 REF: Page and Header: 5, Disease Prevention
OBJ: 4 NAT: Client Needs: Health Promotion and Maintenance
TOP: Chapter: 1 KEY: Integrated Process: Teaching/Learning
BLM: Cognitive Level: Apply NOT: Multiple Choice
6. A nurse in a rehabilitation unit is assisting a client who has had a stroke with relearning how
to perform activities of daily living. What level of prevention is the nurse implementing?
______________________________________________________________________________________________
2|Page
