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UNE CHEM 1005 EXAM
PREPARATION MATERIALS
ADVANCED Q AND A FULL INQUIRY
SET WITH RESPONSES
Which of the following lipoproteins is responsible for carrying
cholesterol from peripheral tissues (i.e skeletal muscle) back to the
liver? ANSWER: HDL


⫸ What is the primary role of LCAT (Lecithin-cholesterol
acyltransferase)? ANSWER: To esterify cholesterol transported by
HDL


⫸ Which enzyme is responsible for transferring triacylglycerol from
VLDL to HDL in exchange for cholesterol? ANSWER: LCAT
(Lecithin-Cholesterol Acyltransferase)


⫸ Which of the following lipoproteins is responsible for the transport
of dietary triacylglycerols in the blood? ANSWER: Chylomicrons


⫸ Several hours after a high carbohydrate meal, the newly
synthesized triacylglycerols in the liver will be packaged into which
of the following lipoproteins? ANSWER: VLDL


⫸ When LDL is taken up by a cell, it will have which of the
following impacts to intracellular cholesterol? ANSWER: Increase in
intracellular cholesterol; Decrease on de novo cholesterol synthesis

, ⫸ Which of the following apoproteins is required for activation of
lipoprotein lipase? ANSWER: ApoCII


⫸ Which of the following apoproteins is present on an LDL particle
and required for uptake by peripheral tissues? ANSWER: ApoB 100


⫸ Which of the following is the full complement of apoproteins
present on VLDLs? ANSWER: ApoB100; ApoCII; ApoE


⫸ Which of the following lipoproteins contains ApoA and ApoCII?
ANSWER: HDL


⫸ Elevated levels of acetyl CoA can be converted into ketone bodies
and can potentially be used as fuel by all of the following tissues
except: ANSWER: liver


⫸ High levels of acetyl CoA within the mitochondria will stimulate
the activity of which of the following enzymes? ANSWER: Pyruvate
carboxylase


⫸ When citrate is shuttled out of the mitochondria for fatty acid
synthesis, the initial reaction by citrate lyase generates which of the
following products? ANSWER: AcetylCoA and oxaloacetate


⫸ Fatty acid beta oxidation generates several products. Which of the
following are direct products of beta oxidation?

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