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HESI RN Pharmacology V1–V3 Bundle Exam 2026/2027:100% Verified Questions, Answers with Rationales| Guaranteed Pass (GRADED A+)

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Ace your nursing pharmacology boards with this comprehensive HESI RN V1–V3 exam bundle featuring hundreds of verified, real-style practice questions. Each question includes detailed, clinical rationales to help you master drug classifications, safety protocols, and dosage calculations. Boost your confidence and guarantee an A+ grade on your upcoming comprehensive assessment.

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HESI RN Pharmacology V1–V3
Bundle Exam 2026/2027:100%
Verified Questions, Answers
with Rationales| Guaranteed
Pass (GRADED A+)
Question 1
A nurse is administering digoxin to a client with heart failure.
Which assessment finding should cause the nurse to withhold
the medication and notify the healthcare provider?
A. Blood pressure 128/76 mmHg
B. Respiratory rate 18 breaths/minute
C. Apical pulse 54 beats/minute
D. Temperature 98.6°F (37°C)
Answer: C. Apical pulse 54 beats/minute
Rationale: Digoxin can cause bradycardia. An apical pulse
below 60 beats/minute in an adult is generally considered a
reason to withhold the medication and notify the healthcare
provider for further evaluation.
Question 2

,A client taking warfarin asks the nurse which laboratory value is
used to monitor the effectiveness of the medication.
A. Hemoglobin
B. INR
C. Platelet count
D. White blood cell count
Answer: B. INR
Rationale: The International Normalized Ratio (INR) is used to
monitor the therapeutic effect of warfarin and guide dosage
adjustments to reduce the risk of bleeding or clot formation.

Question 3
A nurse is teaching a client about nitroglycerin sublingual
tablets. Which statement by the client indicates understanding?
A. "I will swallow the tablet with water."
B. "I should take the tablet after chest pain subsides."
C. "I should place the tablet under my tongue."
D. "I can store the tablets in a weekly pill organizer."
Answer: C. "I should place the tablet under my tongue."
Rationale: Sublingual nitroglycerin should be placed under the
tongue for rapid absorption. It should remain in its original
dark container to maintain potency.
Question 4
A client receives furosemide therapy. Which electrolyte
imbalance should the nurse monitor for?

,A. Hypercalcemia
B. Hypernatremia
C. Hypokalemia
D. Hypermagnesemia
Answer: C. Hypokalemia
Rationale: Furosemide is a loop diuretic that increases
potassium excretion, placing the client at risk for hypokalemia
and associated cardiac dysrhythmias.
Question 5
Which instruction is most important for a client taking
tetracycline?
A. Take with milk.
B. Avoid sun exposure.
C. Increase sodium intake.
D. Take with antacids.
Answer: B. Avoid sun exposure.
Rationale: Tetracycline can cause photosensitivity. Clients
should limit sun exposure and use protective measures when
outdoors.
Question 6
A nurse is preparing to administer insulin lispro. When should
this medication be given?
A. 1 hour before meals
B. At bedtime only

, C. Within 15 minutes of a meal
D. 2 hours after meals
Answer: C. Within 15 minutes of a meal
Rationale: Insulin lispro is a rapid-acting insulin that begins
working quickly and should be administered immediately before
or with meals to prevent hypoglycemia.
Question 7
A client taking an ACE inhibitor develops a persistent dry
cough. Which medication is most likely responsible?
A. Lisinopril
B. Metoprolol
C. Amlodipine
D. Hydrochlorothiazide
Answer: A. Lisinopril
Rationale: A persistent dry cough is a common adverse effect of
ACE inhibitors such as lisinopril due to increased bradykinin
levels.
Question 8
A nurse is caring for a client receiving morphine sulfate. Which
assessment is the priority before administration?
A. Pain level
B. Respiratory rate
C. Bowel sounds
D. Skin turgor

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Uploaded on
September 16, 2026
Number of pages
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Written in
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Type
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