NBME CBSE EXAM LATEST 2026 UPDATED QUESTIONS AND
VERIFIED 100% SOLUTIONS (2026/2027) GRADE: A+|STATUS:
GUARANTEED PASS
a hemolysis - Answers -partial (greening)
strep pneumo
strep viridans
B hemolysis - Answers -complete
Staph
Strep A/B
Listeria
g hemolysis - Answers -none
enterococcus
Staph Aureus virulence factors - Answers -*Protein A*: Binds Fc of Ig
= prevent complement
*Leukocidin* = lyse leukocytes
1|Page
,*Alpha Toxin* = lyse leukocytes
*Hemolysin* = lyse RBC
*Coagulase* = converts fibrinogen into fibrin clot
Toxic Shock Syndrome
(cells, cytokines) - Answers -*TSST* binds Th + APC (macrophage)
--> *IL-2* (Th)
--> *TNFa, IL-1* (macrophage)
Fever, vomit, diarrhea, rash
Hypotension, Shock, high Cr
SSSS
staphylococcal scalded skin - Answers -exotoxin
--> exfoliate - necrosis
What does Staph secrete that can be used by another bug - Answers -NAD+ (f.V)
used by H. flu
MRSA tx - Answers -Vancomycin, daptomycin
linezolid, tigecycline, ceftaroline
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,Enterococcus causes - Answers -UTI
endocarditis
biliary (Acute Bacterial Cholangitis)
bacteremia, meningitis
SSTI (skin/soft tissue)
Enterococcus treatment - Answers -ampicillin/vancomycin
PLUS
Aminoglycoside
VRE treatment - Answers -linezolid
streptogramins: quinupristin, dalfopristin
fosfomycin
H flu requires what to grow - Answers -f.X (hematin)
f.V (NAD+)
= Sheeps blood agar
= Staph aures
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, Strep Pyogens characteristics - Answers -+ bacitracin (pyrrolidonyl arylamidase)
*M protein* (homologous to myosin)
=RESIST PHAGOCYTOSIS
*Molecular Mimicry*: cross reactivity antibodies
Molecular mimicry in which bug - Answers -Strep Pyogens
= Rheumatic Fever
Rheumatic Fever - Answers -*ASO+* (Antistreptolysin O)
Molecular Mimicry
JONES:
Migratory arthritis, Pancarditis (*MR* death), SubQ Nodules,
Erythema marginatum, Sydenham's chorea
Scarlet fever complications - Answers -RF or PSGN
(RF preventable with penicillin)
PSGN on EM and IF - Answers -EM = discrete *subepi humps *
IF = granular IgG C3 (*starry sky*)
4|Page
VERIFIED 100% SOLUTIONS (2026/2027) GRADE: A+|STATUS:
GUARANTEED PASS
a hemolysis - Answers -partial (greening)
strep pneumo
strep viridans
B hemolysis - Answers -complete
Staph
Strep A/B
Listeria
g hemolysis - Answers -none
enterococcus
Staph Aureus virulence factors - Answers -*Protein A*: Binds Fc of Ig
= prevent complement
*Leukocidin* = lyse leukocytes
1|Page
,*Alpha Toxin* = lyse leukocytes
*Hemolysin* = lyse RBC
*Coagulase* = converts fibrinogen into fibrin clot
Toxic Shock Syndrome
(cells, cytokines) - Answers -*TSST* binds Th + APC (macrophage)
--> *IL-2* (Th)
--> *TNFa, IL-1* (macrophage)
Fever, vomit, diarrhea, rash
Hypotension, Shock, high Cr
SSSS
staphylococcal scalded skin - Answers -exotoxin
--> exfoliate - necrosis
What does Staph secrete that can be used by another bug - Answers -NAD+ (f.V)
used by H. flu
MRSA tx - Answers -Vancomycin, daptomycin
linezolid, tigecycline, ceftaroline
2|Page
,Enterococcus causes - Answers -UTI
endocarditis
biliary (Acute Bacterial Cholangitis)
bacteremia, meningitis
SSTI (skin/soft tissue)
Enterococcus treatment - Answers -ampicillin/vancomycin
PLUS
Aminoglycoside
VRE treatment - Answers -linezolid
streptogramins: quinupristin, dalfopristin
fosfomycin
H flu requires what to grow - Answers -f.X (hematin)
f.V (NAD+)
= Sheeps blood agar
= Staph aures
3|Page
, Strep Pyogens characteristics - Answers -+ bacitracin (pyrrolidonyl arylamidase)
*M protein* (homologous to myosin)
=RESIST PHAGOCYTOSIS
*Molecular Mimicry*: cross reactivity antibodies
Molecular mimicry in which bug - Answers -Strep Pyogens
= Rheumatic Fever
Rheumatic Fever - Answers -*ASO+* (Antistreptolysin O)
Molecular Mimicry
JONES:
Migratory arthritis, Pancarditis (*MR* death), SubQ Nodules,
Erythema marginatum, Sydenham's chorea
Scarlet fever complications - Answers -RF or PSGN
(RF preventable with penicillin)
PSGN on EM and IF - Answers -EM = discrete *subepi humps *
IF = granular IgG C3 (*starry sky*)
4|Page
