PCOL 838 UPDATED ACTUAL QUESTIONS
AND CORRECT ANSWERS
COMPREHENSIVE STUDY GUIDE
●● phosphate group
Answer: What group is this?
●● thymidine
Answer: Which DNA nucleoside is this?
●● cytidine
Answer: The molecule depicted above can be referred to as:
A. guanine
B. adeninine
C. adenosine
D. cytosine
E. cytidine
●● A. histidine
recognize it is an amino acid based off carboxylic acid
-it is alpha based on where the amino group is
,-imidazole ring (aromatic compound)
-mediates allergies
Answer: Select the correct name that specifies the amino acid shown
above:
A. Histidine
B. Lysine
C. Glycine
D. Leucine
E. Tryptophan
●● •precursors for peptide and protein biosynthesis
• fuel molecules
• neurotransmitters
• precursors for amino acid-derived biomolecules
including neutrotransmitters etc.
• transport molecules
Answer: What are the purpose of amino acids? What do they do?
●● E. Glutamic acid, cysteine, glycine
Answer: Select the correct amino acids contained in this molecule:
A. methionine,glutamic acid , aspartate
B. glutamic acid, cysteine, alanine
,C. glutamic acid, tryptophan, glucose
D. cystine, glutamic acid, phenylalanine
E. Glutamic acid, cysteine, glycine
●● D. acidic
Answer: The molecule shown below is the amino acid L-histidine
The specific ionization state shown above occurs under which conditions
?
A. neutral
B. basic
C. hydrophilic
D. acidic
E. hydrophobic
●● D. 5
Answer: Consider the structure of a regular hexapeptide. Specify the
number of peptide bonds:
A. 2
B. 3
C. 4
D. 5
E. 6
, ●● The alpha helix (α-helix) is a common motif in the secondary
structure of proteins and is a righthand-spiral conformation
The β-sheet (also β-pleated sheet) is a common motif of regular
secondary structure in proteins. Beta sheets consist of beta strands (also
β-strand) connected laterally by at least two or three backbone hydrogen
bonds
Answer: What are common motifs of secondary structures?
●● • Aromatase, is an enzyme that catalyzes a key step in estrogen
biosynthesis.
• Aromatase is a member of the cytochrome P450 monooxygenase
superfamily.
• During steroidogenesis, aromatase is responsible for the aromatization
of androgens into estrogens.
• Aromatase is a drug target: Aromatase inhibitors are cancer
therapeutics that suppress estrogen biosynthesis, thereby depriving
estrogen-dependent breast cancer cells of this hormone.
Answer: Which reaction does aromatase catalyze?
●● D. Oxidation
Answer: The chemical reaction sequence depicted in the scheme is
catalyzed by the hepatic enzymes ADH and ALDH.
Select the correct term that describes the chemical reaction lading from
acetaldehyde to acetate:
A. Hydrolysis
AND CORRECT ANSWERS
COMPREHENSIVE STUDY GUIDE
●● phosphate group
Answer: What group is this?
●● thymidine
Answer: Which DNA nucleoside is this?
●● cytidine
Answer: The molecule depicted above can be referred to as:
A. guanine
B. adeninine
C. adenosine
D. cytosine
E. cytidine
●● A. histidine
recognize it is an amino acid based off carboxylic acid
-it is alpha based on where the amino group is
,-imidazole ring (aromatic compound)
-mediates allergies
Answer: Select the correct name that specifies the amino acid shown
above:
A. Histidine
B. Lysine
C. Glycine
D. Leucine
E. Tryptophan
●● •precursors for peptide and protein biosynthesis
• fuel molecules
• neurotransmitters
• precursors for amino acid-derived biomolecules
including neutrotransmitters etc.
• transport molecules
Answer: What are the purpose of amino acids? What do they do?
●● E. Glutamic acid, cysteine, glycine
Answer: Select the correct amino acids contained in this molecule:
A. methionine,glutamic acid , aspartate
B. glutamic acid, cysteine, alanine
,C. glutamic acid, tryptophan, glucose
D. cystine, glutamic acid, phenylalanine
E. Glutamic acid, cysteine, glycine
●● D. acidic
Answer: The molecule shown below is the amino acid L-histidine
The specific ionization state shown above occurs under which conditions
?
A. neutral
B. basic
C. hydrophilic
D. acidic
E. hydrophobic
●● D. 5
Answer: Consider the structure of a regular hexapeptide. Specify the
number of peptide bonds:
A. 2
B. 3
C. 4
D. 5
E. 6
, ●● The alpha helix (α-helix) is a common motif in the secondary
structure of proteins and is a righthand-spiral conformation
The β-sheet (also β-pleated sheet) is a common motif of regular
secondary structure in proteins. Beta sheets consist of beta strands (also
β-strand) connected laterally by at least two or three backbone hydrogen
bonds
Answer: What are common motifs of secondary structures?
●● • Aromatase, is an enzyme that catalyzes a key step in estrogen
biosynthesis.
• Aromatase is a member of the cytochrome P450 monooxygenase
superfamily.
• During steroidogenesis, aromatase is responsible for the aromatization
of androgens into estrogens.
• Aromatase is a drug target: Aromatase inhibitors are cancer
therapeutics that suppress estrogen biosynthesis, thereby depriving
estrogen-dependent breast cancer cells of this hormone.
Answer: Which reaction does aromatase catalyze?
●● D. Oxidation
Answer: The chemical reaction sequence depicted in the scheme is
catalyzed by the hepatic enzymes ADH and ALDH.
Select the correct term that describes the chemical reaction lading from
acetaldehyde to acetate:
A. Hydrolysis
