TRAUMA, TUMOR QUESTIONS WITH
VERIFIED ANSWERS [GRADED A+]
Permanent brain damage can occur within _______-_______ minutes of
insufficient blood supply - ✔✔3-5
Describe auto regulation of cerebral blood flow - ✔✔-adjusts diameter of
blood vessels
-ensures consistent and constant blood flow to the brain
What are abnormal factors that affect cerebral blood flow? - ✔✔-CO2, O2,
and acidosis
-cardiac or respiratory arrest
-systemic hemorrhage
-trauma, tumors, cerebral hemorrhage or stroke
©morren2026/2027.Year published 2026.
,How to calculate cerebral perfusion pressure (CPP)? - ✔✔MAP-ICP
What is the normal CPP? - ✔✔60-100 mmHg
A CPP of less than 50mmHg is associated with _____________ and
______________ - ✔✔ischemia and neuronal death
What is the normal ICP? - ✔✔10-15 mmHg
What level ICP would be considered elevated? - ✔✔>20mmHg for 5-10
minutes or longer
What are the 3 ICP components? - ✔✔-CSF
-Intracranial blood volume
-tissue brain volume
Describe the Monro-Kellie Doctrine - ✔✔If one component increases,
another must decrease to maintain ICP
©morren2026/2027.Year published 2026.
, How does arterial pressure affect ICP? - ✔✔if it's too high, the ICP will
also increase
How does venous pressure affect ICP? - ✔✔If venous pressure is too
high, the blood can't be returned to brain (ICP drops)
How does intraabdominal and intrathoracic pressure affect ICP? - ✔✔if
these pressures are high, they will also increase ICP
How does posture affect ICP? - ✔✔-laying down or in Trendelenburg
position will increase ICP
-Sitting up will decrease ICP
How does temperature affect ICP? - ✔✔-high temp= metabolic
malfunction
How do blood gases (CO2 levels) affect ICP? - ✔✔low CO2= low ICP
©morren2026/2027.Year published 2026.