CARN-AP 2nd set Of Questions And
Answers
GABA is the main ________ NT of the CNS - ANSWER -inhibitory
Benzos work by potentiating the effects of GABA by _______ the frequency of
the GABA chloride channel opening - ANSWER -increasing
Alcohol withdrawal is characterized by
________ glutamatergic neurotransmission &
__________GABA functioning - ANSWER -excessive
decreased
Becoming withdrawn and dysphoric is the rebound effect of _______commonly
called comedown or crash. - ANSWER -cocaine
The tachyphylaxis following administration of indirect-acting sympathomimetic
amines such as amphetamines results from what? - ANSWER -the rapid emptying
of synaptic vesicles containing the NTs
Which opioids has both agonist and antagonist activity? - ANSWER -Nalbuphine
Buprenorphine can displace most _____ ______ opiates from mu receptors. -
ANSWER -full agonist
Methylnaltrexone is the quaternary amine of naltrexone that does not cross the
BBB and is a GI-specific opioid ________ that can be prescribed to reverse
refractory opioid-induced __________ - ANSWER -antagonist
constipation
What type of laxatives are contraindicated in opioid-induced constipation -
ANSWER -Bulk-forming laxatives, such as psyllium
A social work client reports that he is "addicted to exercise" and can't spend a day
where he does not exercise. The production of which of the following substances
leads to an addictive cycle in this individual? - ANSWER -Beta-endorphins
, clinical diagnosis of alcoholic hepatitis is determined in a patient with:
- rapid development/worsening of _______ + _____-related complications
- serum total bili > ___
-____ &_____ elevated > 1.5x the upper limit of normal
but < 400 with AST/ALT > ___. - ANSWER -jaundice, liver
3
ALT and AST
2
______ is more specific for liver injury - ANSWER -AST
Nicotine binds_______to nicotinic-_______ receptors - ANSWER -selectively;
cholinergic
The mechanism of action of LSD is the activation of ________ receptors -
ANSWER -serotonin
Lisdexamfetamine dimesylate (Vyvanse) is the first FDA-approved medication to
treat moderate to severe what? - ANSWER -binge-eating disorder.
IV Flumazenil works _________
Can provoke a________ especially in a patient with a chronic history of benzo use.
- ANSWER -immediately
seizure,
The CARN/CARN-AP recognizes that motivational enhancement therapy is based
on the five stages of change. The contemplation stage is when the patient is: -
ANSWER -Aware of the problem and the desired behavioral change
Developing discrepancy between the patient's current situation and their recovery
goals describes what therapeutic modality? - ANSWER -Motivational interviewing
Both the monotherapy and combined therapy inpatient for OUD contain ________
as the active ingredient - ANSWER -buprenorphine
Both monotherapy and combine therapy inpatient for OUD have the propensity to
precipitate withdrawal
T or F - ANSWER -True
, *WARNING*
Assess for SI on what antidepressant?
NEVER _______ abruptly - ANSWER -SSRI
discontinue
NDRI's
Contraindicated in patients undergoing what kind of withdrawal?
May lower _______ threshold
Example of medication: - ANSWER -alcohol or benzodiazepine withdrawal
seizure
Bupropion (Wellbutrin)
SNRI's
Not indicated in patients with ________
If dose is missed, do you make it up? - ANSWER -hypertension
NO!
Examples of SNRIs - ANSWER -Duloxetine (Cymbalta)
Venlafaxine (Effexor)
TCA's:
Contraindicated in patients with what?
Examples Include: - ANSWER -urinary retention and narrow angle glaucoma
AmitriptylINE (Elavil)
DoxepINE (Sinequan)
ClomipramINE (Anafranil)
TCAs may cause:
- sedation,
- flattened ___ waves
- __________ effects - ANSWER -T
anticholinergic
Trazodone:
Answers
GABA is the main ________ NT of the CNS - ANSWER -inhibitory
Benzos work by potentiating the effects of GABA by _______ the frequency of
the GABA chloride channel opening - ANSWER -increasing
Alcohol withdrawal is characterized by
________ glutamatergic neurotransmission &
__________GABA functioning - ANSWER -excessive
decreased
Becoming withdrawn and dysphoric is the rebound effect of _______commonly
called comedown or crash. - ANSWER -cocaine
The tachyphylaxis following administration of indirect-acting sympathomimetic
amines such as amphetamines results from what? - ANSWER -the rapid emptying
of synaptic vesicles containing the NTs
Which opioids has both agonist and antagonist activity? - ANSWER -Nalbuphine
Buprenorphine can displace most _____ ______ opiates from mu receptors. -
ANSWER -full agonist
Methylnaltrexone is the quaternary amine of naltrexone that does not cross the
BBB and is a GI-specific opioid ________ that can be prescribed to reverse
refractory opioid-induced __________ - ANSWER -antagonist
constipation
What type of laxatives are contraindicated in opioid-induced constipation -
ANSWER -Bulk-forming laxatives, such as psyllium
A social work client reports that he is "addicted to exercise" and can't spend a day
where he does not exercise. The production of which of the following substances
leads to an addictive cycle in this individual? - ANSWER -Beta-endorphins
, clinical diagnosis of alcoholic hepatitis is determined in a patient with:
- rapid development/worsening of _______ + _____-related complications
- serum total bili > ___
-____ &_____ elevated > 1.5x the upper limit of normal
but < 400 with AST/ALT > ___. - ANSWER -jaundice, liver
3
ALT and AST
2
______ is more specific for liver injury - ANSWER -AST
Nicotine binds_______to nicotinic-_______ receptors - ANSWER -selectively;
cholinergic
The mechanism of action of LSD is the activation of ________ receptors -
ANSWER -serotonin
Lisdexamfetamine dimesylate (Vyvanse) is the first FDA-approved medication to
treat moderate to severe what? - ANSWER -binge-eating disorder.
IV Flumazenil works _________
Can provoke a________ especially in a patient with a chronic history of benzo use.
- ANSWER -immediately
seizure,
The CARN/CARN-AP recognizes that motivational enhancement therapy is based
on the five stages of change. The contemplation stage is when the patient is: -
ANSWER -Aware of the problem and the desired behavioral change
Developing discrepancy between the patient's current situation and their recovery
goals describes what therapeutic modality? - ANSWER -Motivational interviewing
Both the monotherapy and combined therapy inpatient for OUD contain ________
as the active ingredient - ANSWER -buprenorphine
Both monotherapy and combine therapy inpatient for OUD have the propensity to
precipitate withdrawal
T or F - ANSWER -True
, *WARNING*
Assess for SI on what antidepressant?
NEVER _______ abruptly - ANSWER -SSRI
discontinue
NDRI's
Contraindicated in patients undergoing what kind of withdrawal?
May lower _______ threshold
Example of medication: - ANSWER -alcohol or benzodiazepine withdrawal
seizure
Bupropion (Wellbutrin)
SNRI's
Not indicated in patients with ________
If dose is missed, do you make it up? - ANSWER -hypertension
NO!
Examples of SNRIs - ANSWER -Duloxetine (Cymbalta)
Venlafaxine (Effexor)
TCA's:
Contraindicated in patients with what?
Examples Include: - ANSWER -urinary retention and narrow angle glaucoma
AmitriptylINE (Elavil)
DoxepINE (Sinequan)
ClomipramINE (Anafranil)
TCAs may cause:
- sedation,
- flattened ___ waves
- __________ effects - ANSWER -T
anticholinergic
Trazodone:
