Barkley Women's Health Practice
Exam Latest Exam Update 2026
Graded A+
Table of Contents
1. Introduction and Exam Overview
2. Section 1: Well-Woman Gynecology & Preventive Care (Questions 1-
35)
3. Section 2: Obstetric Care & Prenatal Management (Questions 36-70)
4. Section 3: Gynecologic Disorders & Reproductive Health (Questions
71-105)
5. Section 4: Contraception & Family Planning (Questions 106-130)
6. Section 5: Sexually Transmitted Infections & Genitourinary
Disorders (Questions 131-155)
7. Section 6: Breast Health & Oncology Screening (Questions 156-175)
8. Section 7: Perimenopause, Menopause & Hormone Therapy
(Questions 176-190)
9. Section 8: Pharmacology & Professional Issues (Questions 191-200)
10. Answer Key Summary with Rationales
Introduction and Exam Overview
The Barkley Women's Health Practice Exam is designed to prepare
candidates for the National Certification Corporation (NCC) Women's
Health Care Nurse Practitioner Board Certification (WHNP-BC)
examination. Barkley & Associates has helped over 135,000 NPs prepare
for certification success, and their WHNP review materials cover the full
NCC exam blueprint.
,The NCC WHNP exam content distribution includes: Assessment,
Diagnostic Testing and Interpretation (12%) , Primary Care (13%) ,
Gynecologic and Reproductive Health (33%) , Obstetrics (29%) ,
Pharmacology (10%) , and Professional Issues (3%).
This comprehensive practice exam contains 200 questions covering all
WHNP board certification content areas. Each question includes the
correct answer marked in italics with a detailed rationale in bold.
Section 1: Well-Woman Gynecology & Preventive Care (Questions 1-
35)
1. A 24-year-old female requests her routine cervical cancer
screening. According to ASCCP guidelines, what is the standard
protocol for her age group?
A. Cytology alone every 3 years
B. Primary HPV testing every 5 years
C. Cytology with HPV co-testing every 3 years
D. Co-testing every 5 years
Correct Answer: A
Rationale: ASCCP guidelines mandate cytology alone for ages 21-29.
Primary HPV testing or co-testing is avoided in this age group due
to high transient viral clearance rates, which could lead to
unnecessary procedures.
2. A 35-year-old female presents for a routine checkup. What is the
preferred cervical cancer screening strategy for her age group?
A. Cytology alone every 3 years
B. Primary HPV testing every 5 years
C. Co-testing every 10 years
D. Cytology every 5 years
Correct Answer: B
,Rationale: For ages 30-65, screening with primary HPV testing every
5 years or co-testing (cytology + HPV) every 5 years provides
optimal reassurance and sensitivity.
3. A 22-year-old female's Pap result shows ASC-US (Atypical
Squamous Cells of Undetermined Significance). What is the next
step?
A. Immediate colposcopy
B. Repeat cytology in 12 months
C. Perform reflex HPV testing
D. Perform LEEP procedure
Correct Answer: B
Rationale: In patients aged 21-24, low-grade lesions frequently
regress spontaneously. Repeat cytology in 12 months minimizes
unnecessary cervical procedures.
4. A 27-year-old female presents with LSIL and positive HPV test.
What is the appropriate next step?
A. Repeat Pap in 12 months
B. Immediate colposcopy
C. Perform LEEP procedure
D. Repeat Pap in 6 months
Correct Answer: B
Rationale: For women age 25 and older with LSIL and positive HPV,
immediate colposcopy is required to check for underlying high-
grade dysplasia.
5. A 40-year-old woman has a Pap smear showing HSIL. What is the
next best step?
A. Repeat Pap smear in one year
B. Colposcopy with directed biopsy
C. Loop electrosurgical excision procedure (LEEP)
D. Hysterectomy
, Correct Answer: B
Rationale: HSIL on cervical cytology requires colposcopy with
directed biopsy to obtain histologic confirmation and rule out
invasive cancer.
6. A 30-year-old woman has a Pap test with HPV co-testing. The
result is NILM and HPV negative. The recommended follow-up is:
A. Repeat co-testing in 1 year
B. Repeat co-testing in 3 years
C. Repeat co-testing in 5 years
D. Colposcopy
Correct Answer: C
Rationale: For women aged 30-65 with a negative co-test (NILM and
HPV negative), routine screening is recommended no sooner than
every 5 years.
7. Which of the following is a known risk factor for cervical cancer?
A. Multiparity
B. Persistent infection with high-risk HPV types 16 and 18
C. Early menopause
D. Endometriosis
Correct Answer: B
Rationale: Persistent infection with oncogenic (high-risk) HPV types,
especially 16 and 18, is the primary cause of cervical cancer.
8. The quadrivalent HPV vaccine (Gardasil) protects against which
HPV types?
A. 6, 11, 16, 18
B. 16, 18, 31, 33
C. 31, 33, 45, 52
D. 6, 11, 16, 18, 31, 33, 45, 52, 58
Correct Answer: A
Exam Latest Exam Update 2026
Graded A+
Table of Contents
1. Introduction and Exam Overview
2. Section 1: Well-Woman Gynecology & Preventive Care (Questions 1-
35)
3. Section 2: Obstetric Care & Prenatal Management (Questions 36-70)
4. Section 3: Gynecologic Disorders & Reproductive Health (Questions
71-105)
5. Section 4: Contraception & Family Planning (Questions 106-130)
6. Section 5: Sexually Transmitted Infections & Genitourinary
Disorders (Questions 131-155)
7. Section 6: Breast Health & Oncology Screening (Questions 156-175)
8. Section 7: Perimenopause, Menopause & Hormone Therapy
(Questions 176-190)
9. Section 8: Pharmacology & Professional Issues (Questions 191-200)
10. Answer Key Summary with Rationales
Introduction and Exam Overview
The Barkley Women's Health Practice Exam is designed to prepare
candidates for the National Certification Corporation (NCC) Women's
Health Care Nurse Practitioner Board Certification (WHNP-BC)
examination. Barkley & Associates has helped over 135,000 NPs prepare
for certification success, and their WHNP review materials cover the full
NCC exam blueprint.
,The NCC WHNP exam content distribution includes: Assessment,
Diagnostic Testing and Interpretation (12%) , Primary Care (13%) ,
Gynecologic and Reproductive Health (33%) , Obstetrics (29%) ,
Pharmacology (10%) , and Professional Issues (3%).
This comprehensive practice exam contains 200 questions covering all
WHNP board certification content areas. Each question includes the
correct answer marked in italics with a detailed rationale in bold.
Section 1: Well-Woman Gynecology & Preventive Care (Questions 1-
35)
1. A 24-year-old female requests her routine cervical cancer
screening. According to ASCCP guidelines, what is the standard
protocol for her age group?
A. Cytology alone every 3 years
B. Primary HPV testing every 5 years
C. Cytology with HPV co-testing every 3 years
D. Co-testing every 5 years
Correct Answer: A
Rationale: ASCCP guidelines mandate cytology alone for ages 21-29.
Primary HPV testing or co-testing is avoided in this age group due
to high transient viral clearance rates, which could lead to
unnecessary procedures.
2. A 35-year-old female presents for a routine checkup. What is the
preferred cervical cancer screening strategy for her age group?
A. Cytology alone every 3 years
B. Primary HPV testing every 5 years
C. Co-testing every 10 years
D. Cytology every 5 years
Correct Answer: B
,Rationale: For ages 30-65, screening with primary HPV testing every
5 years or co-testing (cytology + HPV) every 5 years provides
optimal reassurance and sensitivity.
3. A 22-year-old female's Pap result shows ASC-US (Atypical
Squamous Cells of Undetermined Significance). What is the next
step?
A. Immediate colposcopy
B. Repeat cytology in 12 months
C. Perform reflex HPV testing
D. Perform LEEP procedure
Correct Answer: B
Rationale: In patients aged 21-24, low-grade lesions frequently
regress spontaneously. Repeat cytology in 12 months minimizes
unnecessary cervical procedures.
4. A 27-year-old female presents with LSIL and positive HPV test.
What is the appropriate next step?
A. Repeat Pap in 12 months
B. Immediate colposcopy
C. Perform LEEP procedure
D. Repeat Pap in 6 months
Correct Answer: B
Rationale: For women age 25 and older with LSIL and positive HPV,
immediate colposcopy is required to check for underlying high-
grade dysplasia.
5. A 40-year-old woman has a Pap smear showing HSIL. What is the
next best step?
A. Repeat Pap smear in one year
B. Colposcopy with directed biopsy
C. Loop electrosurgical excision procedure (LEEP)
D. Hysterectomy
, Correct Answer: B
Rationale: HSIL on cervical cytology requires colposcopy with
directed biopsy to obtain histologic confirmation and rule out
invasive cancer.
6. A 30-year-old woman has a Pap test with HPV co-testing. The
result is NILM and HPV negative. The recommended follow-up is:
A. Repeat co-testing in 1 year
B. Repeat co-testing in 3 years
C. Repeat co-testing in 5 years
D. Colposcopy
Correct Answer: C
Rationale: For women aged 30-65 with a negative co-test (NILM and
HPV negative), routine screening is recommended no sooner than
every 5 years.
7. Which of the following is a known risk factor for cervical cancer?
A. Multiparity
B. Persistent infection with high-risk HPV types 16 and 18
C. Early menopause
D. Endometriosis
Correct Answer: B
Rationale: Persistent infection with oncogenic (high-risk) HPV types,
especially 16 and 18, is the primary cause of cervical cancer.
8. The quadrivalent HPV vaccine (Gardasil) protects against which
HPV types?
A. 6, 11, 16, 18
B. 16, 18, 31, 33
C. 31, 33, 45, 52
D. 6, 11, 16, 18, 31, 33, 45, 52, 58
Correct Answer: A
