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EVOLVE ELSEVIER HESI MED-SURG 2026/2027 | 350 Practice Questions & Answers with Detailed Rationales | Cardiac, Respiratory, GI, Renal, Endocrine, Neuro, Oncology & More

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Prepare for the Evolve Elsevier HESI Medical-Surgical Nursing exam with 350 comprehensive practice questions, correct answers, and detailed rationales. This resource covers cardiac, respiratory, GI, renal, endocrine, neurological, musculoskeletal, hematology, oncology, infectious disease, perioperative care, fluids & electrolytes, pharmacology, prioritization, delegation, and SATA-style questions. Designed to strengthen clinical judgment, reinforce high-yield concepts, and build confidence for HESI Med-Surg and NCLEX-style testing.

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EVOLVE ELSEVIER HESI MED-SURG 2026/2027 | 350
Practice Questions & Answers with Detailed Rationales
| Cardiac, Respiratory, GI, Renal, Endocrine, Neuro,
Oncology & More

,Q1. A client is diagnosed with an acute small bowel obstruction. Which assessment finding
requires the most immediate intervention by the nurse?

A. Fever of 102°F
B. Blood pressure of 150/90 mm Hg
C. Abdominal cramping
D. Dry mucous membranes

ANSWER: A. Fever of 102°F

Rationale: A sudden elevation in temperature in a client with a bowel obstruction may indicate
peritonitis or bowel perforation, which requires immediate intervention. Abdominal cramping
is expected with obstruction, while dry mucous membranes indicate fluid-volume deficit that
requires treatment but is generally less immediately life-threatening. Mild hypertension is not
the priority.



Q2. When assessing a client with primary aldosteronism, the nurse expects which laboratory
finding?

A. Increased serum sodium
B. Increased serum phosphate
C. Decreased serum potassium
D. Decreased serum glucose

ANSWER: C. Decreased serum potassium

Rationale: Excess aldosterone promotes sodium and water retention while increasing
potassium excretion by the kidneys. Therefore, hypokalemia is a characteristic finding of
primary aldosteronism.



Q3.

A client with heart failure reports increasing shortness of breath and wakes at night feeling
unable to breathe. Which finding is most concerning?

,A. 1+ bilateral ankle edema
B. Weight gain of 1 kg in 24 hours
C. Oxygen saturation of 86%
D. Blood pressure of 138/84 mm Hg

ANSWER: C. Oxygen saturation of 86%

Rationale: An oxygen saturation of 86% indicates significant hypoxemia and requires immediate
assessment and intervention. The weight gain and edema suggest fluid retention but are not as
immediately threatening as impaired oxygenation.



Q4.

A client with chronic obstructive pulmonary disease (COPD) is receiving oxygen. Which oxygen
saturation is generally an appropriate target for many clients with chronic CO₂ retention?

A. 70%–75%
B. 80%–84%
C. 88%–92%
D. 98%–100%

ANSWER: C. 88%–92%

Rationale: Many clients with COPD who are at risk for hypercapnia are maintained around 88%–
92%, unless a different target is prescribed. Excessive oxygen administration can worsen
hypercapnia in susceptible clients.



Q5.

A client with suspected myocardial infarction reports severe crushing chest pain. Which
medication should the nurse anticipate administering unless contraindicated?

A. Acetaminophen
B. Aspirin
C. Warfarin
D. Furosemide

ANSWER: B. Aspirin

Rationale: Aspirin inhibits platelet aggregation and is a key early treatment for suspected acute
coronary syndrome when there is no contraindication.

, Q6.

A client receiving digoxin has an apical pulse of 52 beats/minute. What should the nurse do
first?

A. Administer the medication with food
B. Give an additional dose
C. Hold the medication and notify the provider
D. Encourage ambulation

ANSWER: C. Hold the medication and notify the provider

Rationale: Digoxin can cause bradycardia. An adult apical pulse below the commonly accepted
threshold of 60 beats/minute warrants holding the medication and further evaluation.



Q7.

Which assessment finding is most consistent with hypokalemia?

A. Muscle weakness
B. Bounding pulse
C. Hyperactive reflexes
D. Severe hypertension

ANSWER: A. Muscle weakness

Rationale: Hypokalemia can cause muscle weakness, fatigue, dysrhythmias, and decreased
gastrointestinal motility.



Q8.

A client with diabetes is confused, diaphoretic, and trembling. Which condition should the nurse
suspect?

A. Hypernatremia
B. Hypoglycemia
C. Hypercalcemia
D. Hyperglycemia

ANSWER: B. Hypoglycemia

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