NURS 498 MIDTERM 1 QUESTIONS AND ANSWERS | NURS 498
STUDY GUIDE & PRACTICE TEST 2026/2027
a. Increased susceptibility to infections
Rationale: Neurotoxicity and confusion may be a problem with some immunosuppressants but a
heightened susceptibility to opportunistic infections is a major risk factor for immunosuppressed
patients. - ANS ✔✔Which potential problem is of most concern for a patient receiving
immunosuppressant drugs?
a. Increased susceptibility to infections
b. Orthostatic hypotension
c. Neurotoxicity
d. Confusion
b. Bone marrow suppression - ANS ✔✔A patient with active HIV has been taking zidovudine (Retrovir®).
Which potential adverse effect may limit the length of time this medication can be taken?
a. hepatomegaly
b. Bone marrow suppression
c. Lactic acidosis
d. fatigue
b. A client who tested positive for HIV 3 years ago and has developed tuberculosis - ANS ✔✔The nurse
working in an HIV testing and treatment clinic plans teaching about antiretroviral therapy for which of
the following clients?
a. A client with persistent generalized lymphadenopathy who was exposed to HIV 2 years previously
b. A client who tested positive for HIV 3 years ago and has developed tuberculosis
c. A client who was infected with HIV 10 years ago and has a CD4+ T-cell count of 650/μL
d. A male health care worker who is HIV negative but has unprotected sex with men
a. Latent tuberculosis - ANS ✔✔Before administering methitrexate to a patient, what is most important
for the nurse to assess?
a. Latent tuberculosis
b. Allergy to eggs
c. Congestive heart failure
d. hypothyroidism
b. Leukopenia
Rationale: Leukopenia is an expected adverse effect of azathioprine therapy. - ANS ✔✔A female patient
has started azathioprine (Imuran®) therapy in preparation for her kidney transplant surgery. Which
expected adverse effect of azathioprine therapy should the nurse tell the patient about?
STUDY GUIDE & PRACTICE TEST 2026/2027
a. Increased susceptibility to infections
Rationale: Neurotoxicity and confusion may be a problem with some immunosuppressants but a
heightened susceptibility to opportunistic infections is a major risk factor for immunosuppressed
patients. - ANS ✔✔Which potential problem is of most concern for a patient receiving
immunosuppressant drugs?
a. Increased susceptibility to infections
b. Orthostatic hypotension
c. Neurotoxicity
d. Confusion
b. Bone marrow suppression - ANS ✔✔A patient with active HIV has been taking zidovudine (Retrovir®).
Which potential adverse effect may limit the length of time this medication can be taken?
a. hepatomegaly
b. Bone marrow suppression
c. Lactic acidosis
d. fatigue
b. A client who tested positive for HIV 3 years ago and has developed tuberculosis - ANS ✔✔The nurse
working in an HIV testing and treatment clinic plans teaching about antiretroviral therapy for which of
the following clients?
a. A client with persistent generalized lymphadenopathy who was exposed to HIV 2 years previously
b. A client who tested positive for HIV 3 years ago and has developed tuberculosis
c. A client who was infected with HIV 10 years ago and has a CD4+ T-cell count of 650/μL
d. A male health care worker who is HIV negative but has unprotected sex with men
a. Latent tuberculosis - ANS ✔✔Before administering methitrexate to a patient, what is most important
for the nurse to assess?
a. Latent tuberculosis
b. Allergy to eggs
c. Congestive heart failure
d. hypothyroidism
b. Leukopenia
Rationale: Leukopenia is an expected adverse effect of azathioprine therapy. - ANS ✔✔A female patient
has started azathioprine (Imuran®) therapy in preparation for her kidney transplant surgery. Which
expected adverse effect of azathioprine therapy should the nurse tell the patient about?
