NURS 2245 medications | Macomb Community College | Questions with 100%
Verified Answers | Latest Update
Question: HMG-CoA Reductase Inhibitors (Statins)
Answer:
Actions
•Inhibit synthesis & increase clearance
•Pleiotropic effects
-decrease osteoporosis, increase well being, decrease cancer growth, decrease type 2
diabetes, decrease delirium in ICU pts Teaching
•Take in evening
•Avoid grapefruit
•Monitor CK levels
Examples
•Simvastatin (Zocor)
•Atrovastatin (Lipitor)
•Rosuvastatin (Crestor)
Question: Fibric Acid Derivatives
Answer:
Actions
• Reduces LDL, VLDL and triglycerides, increases HDL levels
•Appears to have a beneficial effect on insulin resistance
•Used alone or in conjunction with statins
Side Effects GI distress Similar to statins ↑incidence of liver problems and gallstones Teaching
Avoid ETOH, can cause elevated triglycerides Examples fenofibrate (Tricor, Lipofen, Trilipix,
Lipidil) gemfibrozil (Lopid)
Question: Nicoinic Acid (Niacin)
Answer:
Action high doses lower VLDL and elevated HDL Types OTC and Rx Side effects flushing
and itching increased uric acid increased blood sugar
Question: Cholesterol Absorption Inhibitor
Answer:
Action inhibits absorption in the small intestine Teaching give in addition to statin Examples
ezetimide (Zetia)
, Question: Bile Acid Resins
Answer:
Action
•Decrease reabsorption of bile acids in small intestine
•to create more bile acids, liver must pull LDL from plasma
Unlabeled use diarrhea Side effects
•Constipation, flatulence
•decreased absorption of other meds
Examples
•Cholestyramine (Questran)
•Colestipol (Colestid)
•Colesevelam (Welchol)
Question: When evaluating the effect of lipid loweing therapy, the
nurse would monitor for
Answer:
decreased LDL and increased HDL levels
3 multiple choice options
Question: Nitroglycerin (NTG)
Answer:
Action
•Dilates coronary arteries, peripheral arteries and veins
•Analgesic for ischemic chest pain
Dosing
•1 tab or 1 spray (0.4 mg) SL every 3 -5 min x 3 until pain relief or hypotension
•Continuous IV if ongoing chest discomfort, hypertension or pulmonary congestion
Contraindicated
•SBP < __ mmHg
•HR < 50 bpm or > 100 bpm
•Recent phosphodiesterase inhibitor use
–sildenfanil (Viagra) –vardenfamil (Levitra) –tadafil (Cialis)
•RV MI
Caution
•Inferior MI
ALERT: Must evaluate for hypotension before & after administration
Verified Answers | Latest Update
Question: HMG-CoA Reductase Inhibitors (Statins)
Answer:
Actions
•Inhibit synthesis & increase clearance
•Pleiotropic effects
-decrease osteoporosis, increase well being, decrease cancer growth, decrease type 2
diabetes, decrease delirium in ICU pts Teaching
•Take in evening
•Avoid grapefruit
•Monitor CK levels
Examples
•Simvastatin (Zocor)
•Atrovastatin (Lipitor)
•Rosuvastatin (Crestor)
Question: Fibric Acid Derivatives
Answer:
Actions
• Reduces LDL, VLDL and triglycerides, increases HDL levels
•Appears to have a beneficial effect on insulin resistance
•Used alone or in conjunction with statins
Side Effects GI distress Similar to statins ↑incidence of liver problems and gallstones Teaching
Avoid ETOH, can cause elevated triglycerides Examples fenofibrate (Tricor, Lipofen, Trilipix,
Lipidil) gemfibrozil (Lopid)
Question: Nicoinic Acid (Niacin)
Answer:
Action high doses lower VLDL and elevated HDL Types OTC and Rx Side effects flushing
and itching increased uric acid increased blood sugar
Question: Cholesterol Absorption Inhibitor
Answer:
Action inhibits absorption in the small intestine Teaching give in addition to statin Examples
ezetimide (Zetia)
, Question: Bile Acid Resins
Answer:
Action
•Decrease reabsorption of bile acids in small intestine
•to create more bile acids, liver must pull LDL from plasma
Unlabeled use diarrhea Side effects
•Constipation, flatulence
•decreased absorption of other meds
Examples
•Cholestyramine (Questran)
•Colestipol (Colestid)
•Colesevelam (Welchol)
Question: When evaluating the effect of lipid loweing therapy, the
nurse would monitor for
Answer:
decreased LDL and increased HDL levels
3 multiple choice options
Question: Nitroglycerin (NTG)
Answer:
Action
•Dilates coronary arteries, peripheral arteries and veins
•Analgesic for ischemic chest pain
Dosing
•1 tab or 1 spray (0.4 mg) SL every 3 -5 min x 3 until pain relief or hypotension
•Continuous IV if ongoing chest discomfort, hypertension or pulmonary congestion
Contraindicated
•SBP < __ mmHg
•HR < 50 bpm or > 100 bpm
•Recent phosphodiesterase inhibitor use
–sildenfanil (Viagra) –vardenfamil (Levitra) –tadafil (Cialis)
•RV MI
Caution
•Inferior MI
ALERT: Must evaluate for hypotension before & after administration
