9/13/26, 4:16 AM UNIT 4 PATHO 545 Flashcards | Quizlet
QUESTION-HEMO-ERYTHROPOIESIS-NUTRITION answer/rationale
A person has an inadequate intake of folic acid what will 2. impaired DNA synthesis folate is the second most importanat vit for erythrocyte
happen to this person RBC's production and maturation folate is necessary for DNA synthesis being a
componenet of three of the four DNA basis (thymine, adenine, and guanine,)and RNA
1. impaired iron metabolism synthesis.
2. impaired DNA synthesis
3. impaired hemoglobin synthesis wrong
4. impaired heme metabolism 1. iron metabolims= VIT C
3. hemoglobin synthesis=IRON
4. heme metabolism= vit b6, E, pantothenic acid.
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,9/13/26, 4:16 AM UNIT 4 PATHO 545 Flashcards | Quizlet
QUESTION-HEMO-HEMOSTATISIS answer rationale
Von Willebrand factor is 2. necessary for platelet adhesion. platelet adhesion is mostly mediated by the
binding of platelet surface receptor glycoprotein-lb (GPlb) (in complex with clotting
1. essential for platelet activation factor IX and V) to van Willebrand factor (vWF) protein is found in the subendothelial
2. necessary for platelet adhesion matrix and is released by endothelial cells and platelets.
3. needed to stimulate platelet aggregation
4. required for hageman factor to degrade platelets. wrong
1. platelet activation=reorganization of the platelet cytoskeleton
3. stimulate platelet aggregation=TXA2 and ADP which induce functional fibrinogen
receptors
4. hageman factor to degrade platelets=intrinsic pathway for clotting is activated in
plasma contacts negatively charged subendothelial substances exposed by vascular
injury.
QUESTION-HEMO-CHILD answer/rationale
Which info is correct regarding infant or child's hematologic 4. polycythemia of the newborn occurs from the hypoxic intrauterine environment
system. the hypoxic intrauterine environment stimulates erythropoietin production in the
fetus and accelerates fetal erythropoiesis, producing polycythemia (excessive
1. blood cell counts decrease at birth from the loss of proliferation of erythrocyte precursors) of the newborn)
blood and then increase throughout childhood
2. immediately after birth of a full term neonate, the wrong.
reticulocyte count decrases
3. platelets increase at birth and decrease to adult levels 1. blood cell count decreases=count tend to rise at birth
4. polycythemia of the newborn occurs from hypoxic 2. reticulocyte decrease= active fetal erythropoiesis results in large number of
intrauterine environments. reticulocytes.
3. platelets increase=comparable with adults.
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,9/13/26, 4:16 AM UNIT 4 PATHO 545 Flashcards | Quizlet
QUESTION-ERYTHROCYTE-ANEMIA answer/rationale
A person with a gastrectomy is seen in the clinic for 4. pernicious anemia- pernicious anemia is caused by inadequate or absent
generalized weakness, fatigue, difficulty walking, and production of intrinsic factor (IF) by gastric parietal cells. Complete or partial
abdominal pain. The nurse suspects this individual has: removal of the stomach (gastrectomy) causes (IF) deficiency.
1. folate deficiency anemia wrong
2. eryptosis anemia
3. polycythemia anemia 1. folate deficiency= produces scales and fissures of the lips and mouth, stomatitis,
4. pernicious anemia buccal and tongue ulcers, dysphagia, flatulence, and water diarrhea.
2. eryptosis-premature death of damaged erythrocytes, eryptosis, is a common
mechanism of cellular loss in individuals with anemias secondary to deficiencies of
iron, infections, chronic diseases and myelodysplastic syndrome
3. polycythemia=conditions in which erythrocyte numbers or volume is excessive.
QUESTION-ERYTHROCYTE-ANEMIA answer/rationale
a person is admitted with an autoimmune disease directed 1. aplastic anemia is the result of bone marrow suppression or failure caused by an
against the hematopoietic stem cells. the nurse knows this autoimmune disease directed against the hematopoietic stem cells that produces
will produce. pancytopenia.
1. aplastic anemia wrong
2. iron deficiency anemia
3. sideroblastic anemia 2. iron deficiency anemia can arise from one of two different etiologies or
4. fanconi anemia combination of both; inadequate dietary intake or excessive blood loss
3. sideroblastic anemias are a heterogeneous group of disorders characterized by
anemia of varying severity caused by a defect in mitochondrial heme synthesis
4. fanconi anemia is a rare genetic anemia characterized by pancytopenia resulting
from defects in DNA repair. this anemia develops early in life and is accompanied by
multiple congenital anomalies.
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, 9/13/26, 4:16 AM UNIT 4 PATHO 545 Flashcards | Quizlet
QUESTION-ERYTHROCYTE-ANEMIA answer/rational
Anemia of chronic disease is caused by. 3. reduced response to erythropoietin ACD results from a combination of 1)
decreased erythrocyte life span 2) suppressed production of erythropoietin 3)
1. immunoglobulin G (IgG) binding to erythrocytes at ineffective bone marrow metabolism and iron sequestration in macrophages.
normal body temperatures.
2. autoantibodies against erythrocytes surface antigens wrong
3. reduced response to erythropoietin
4. paroxysmal nocturnal hemoglobinuria. 1. warm autoimmune hemolytic anemia is caused by IgG that binds optimally to
erythrocytes at normal bod temperature.
2. autoimmune hemolytic anemias are acquired disorders caused by autoantibodies
against antigens normally on the surface of erythrocytes.
4. paroxysmal nocturnal hemoglobinuria= results from mutation in the X-linked gene
for phosphatidylinositol glycan
WLH-MONO-AKA EBSTEIN BARR VIRUS Clinical manifestations
Malaise, arthralgia
What is mononucleosis. Classic triad of symptoms: Fever, pharyngitis, and lymphadenopathy of the cervical
lymph nodes
Diagnostic test
Mono-spot qualitative test for heterophilic antibodies
Treatment
Rest and alleviation of symptoms with analgesics and antipyretics and penicillin or
erythromycin
Ibuprofen, not aspirin, for children and adolescents because of reported incidence
of Reyes syndrome
what are the complications of mononucleosis
complications are rare may develop enlargement of spleen and liver. resulting in
rupture of spleen. other fatalities are r/t hepatic failure extensive bacterial infection
or viral myocarditis.
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QUESTION-HEMO-ERYTHROPOIESIS-NUTRITION answer/rationale
A person has an inadequate intake of folic acid what will 2. impaired DNA synthesis folate is the second most importanat vit for erythrocyte
happen to this person RBC's production and maturation folate is necessary for DNA synthesis being a
componenet of three of the four DNA basis (thymine, adenine, and guanine,)and RNA
1. impaired iron metabolism synthesis.
2. impaired DNA synthesis
3. impaired hemoglobin synthesis wrong
4. impaired heme metabolism 1. iron metabolims= VIT C
3. hemoglobin synthesis=IRON
4. heme metabolism= vit b6, E, pantothenic acid.
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,9/13/26, 4:16 AM UNIT 4 PATHO 545 Flashcards | Quizlet
QUESTION-HEMO-HEMOSTATISIS answer rationale
Von Willebrand factor is 2. necessary for platelet adhesion. platelet adhesion is mostly mediated by the
binding of platelet surface receptor glycoprotein-lb (GPlb) (in complex with clotting
1. essential for platelet activation factor IX and V) to van Willebrand factor (vWF) protein is found in the subendothelial
2. necessary for platelet adhesion matrix and is released by endothelial cells and platelets.
3. needed to stimulate platelet aggregation
4. required for hageman factor to degrade platelets. wrong
1. platelet activation=reorganization of the platelet cytoskeleton
3. stimulate platelet aggregation=TXA2 and ADP which induce functional fibrinogen
receptors
4. hageman factor to degrade platelets=intrinsic pathway for clotting is activated in
plasma contacts negatively charged subendothelial substances exposed by vascular
injury.
QUESTION-HEMO-CHILD answer/rationale
Which info is correct regarding infant or child's hematologic 4. polycythemia of the newborn occurs from the hypoxic intrauterine environment
system. the hypoxic intrauterine environment stimulates erythropoietin production in the
fetus and accelerates fetal erythropoiesis, producing polycythemia (excessive
1. blood cell counts decrease at birth from the loss of proliferation of erythrocyte precursors) of the newborn)
blood and then increase throughout childhood
2. immediately after birth of a full term neonate, the wrong.
reticulocyte count decrases
3. platelets increase at birth and decrease to adult levels 1. blood cell count decreases=count tend to rise at birth
4. polycythemia of the newborn occurs from hypoxic 2. reticulocyte decrease= active fetal erythropoiesis results in large number of
intrauterine environments. reticulocytes.
3. platelets increase=comparable with adults.
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,9/13/26, 4:16 AM UNIT 4 PATHO 545 Flashcards | Quizlet
QUESTION-ERYTHROCYTE-ANEMIA answer/rationale
A person with a gastrectomy is seen in the clinic for 4. pernicious anemia- pernicious anemia is caused by inadequate or absent
generalized weakness, fatigue, difficulty walking, and production of intrinsic factor (IF) by gastric parietal cells. Complete or partial
abdominal pain. The nurse suspects this individual has: removal of the stomach (gastrectomy) causes (IF) deficiency.
1. folate deficiency anemia wrong
2. eryptosis anemia
3. polycythemia anemia 1. folate deficiency= produces scales and fissures of the lips and mouth, stomatitis,
4. pernicious anemia buccal and tongue ulcers, dysphagia, flatulence, and water diarrhea.
2. eryptosis-premature death of damaged erythrocytes, eryptosis, is a common
mechanism of cellular loss in individuals with anemias secondary to deficiencies of
iron, infections, chronic diseases and myelodysplastic syndrome
3. polycythemia=conditions in which erythrocyte numbers or volume is excessive.
QUESTION-ERYTHROCYTE-ANEMIA answer/rationale
a person is admitted with an autoimmune disease directed 1. aplastic anemia is the result of bone marrow suppression or failure caused by an
against the hematopoietic stem cells. the nurse knows this autoimmune disease directed against the hematopoietic stem cells that produces
will produce. pancytopenia.
1. aplastic anemia wrong
2. iron deficiency anemia
3. sideroblastic anemia 2. iron deficiency anemia can arise from one of two different etiologies or
4. fanconi anemia combination of both; inadequate dietary intake or excessive blood loss
3. sideroblastic anemias are a heterogeneous group of disorders characterized by
anemia of varying severity caused by a defect in mitochondrial heme synthesis
4. fanconi anemia is a rare genetic anemia characterized by pancytopenia resulting
from defects in DNA repair. this anemia develops early in life and is accompanied by
multiple congenital anomalies.
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, 9/13/26, 4:16 AM UNIT 4 PATHO 545 Flashcards | Quizlet
QUESTION-ERYTHROCYTE-ANEMIA answer/rational
Anemia of chronic disease is caused by. 3. reduced response to erythropoietin ACD results from a combination of 1)
decreased erythrocyte life span 2) suppressed production of erythropoietin 3)
1. immunoglobulin G (IgG) binding to erythrocytes at ineffective bone marrow metabolism and iron sequestration in macrophages.
normal body temperatures.
2. autoantibodies against erythrocytes surface antigens wrong
3. reduced response to erythropoietin
4. paroxysmal nocturnal hemoglobinuria. 1. warm autoimmune hemolytic anemia is caused by IgG that binds optimally to
erythrocytes at normal bod temperature.
2. autoimmune hemolytic anemias are acquired disorders caused by autoantibodies
against antigens normally on the surface of erythrocytes.
4. paroxysmal nocturnal hemoglobinuria= results from mutation in the X-linked gene
for phosphatidylinositol glycan
WLH-MONO-AKA EBSTEIN BARR VIRUS Clinical manifestations
Malaise, arthralgia
What is mononucleosis. Classic triad of symptoms: Fever, pharyngitis, and lymphadenopathy of the cervical
lymph nodes
Diagnostic test
Mono-spot qualitative test for heterophilic antibodies
Treatment
Rest and alleviation of symptoms with analgesics and antipyretics and penicillin or
erythromycin
Ibuprofen, not aspirin, for children and adolescents because of reported incidence
of Reyes syndrome
what are the complications of mononucleosis
complications are rare may develop enlargement of spleen and liver. resulting in
rupture of spleen. other fatalities are r/t hepatic failure extensive bacterial infection
or viral myocarditis.
https://quizlet.com/124379727/unit-4-patho-545-flash-cards/?funnelUUID=8523093f-f7f7-4286-9871-5ef386122d26 6/75
