ACUTE LYMPHOBLASTIC LEUKEMIA
EXAMINATION TEST COMPLETE
QUESTIONS AND SOLUTIONS
●● What happens when abnormal white blood cells are produced in
ALL?
Answer: The body cannot fight infection.
●● What does the bone marrow make?
Answer: Immature cells known as blood stem cells.
●● What can a blood stem cell become?
Answer: Either a lymphoid stem cell or a myeloid stem cell.
●● What does a lymphoid stem cell become?
Answer: A lymphoblast, which turns into a white blood cell.
●● What are the three types of cells that lymphoblasts can become?
Answer: B lymphocytes, T lymphocytes, or natural killer cells.
●● What do B lymphocytes do?
Answer: Fight infection and make antibodies.
,●● What do T lymphocytes do?
Answer: Help the B lymphocytes.
●● What do natural killer cells do?
Answer: Attack viruses and cancer cells.
●● Flashcard 10Q: What happens in ALL?
Answer: A: The bone marrow makes more lymphocytes than needed.
●● What happens when too many B or T lymphocytes are produced?
Answer: A: They increase in the blood and bone marrow, causing
healthy WBCs, RBCs, and platelets to be outnumbered.
●● What is the etiology of ALL?
Answer: A: Unknown.
●● What environmental factors may be associated with ALL?
Answer: A: Ionizing radiation, benzene, and previous exposure to
radiotherapy or chemotherapy.
●● What is a risk factor for developing ALL?
Answer: A: Prior exposure to ionizing radiation.
, ●● What types of radiation exposure can increase the risk of ALL?
Answer: A: Therapeutic radiation or radiation from nuclear accidents.
●● What previous treatment increases the risk of ALL?
Answer: A: A history of chemotherapy.
●● What is the incidence pattern of ALL?
Answer: A: Bimodal, with a primary peak in children under age 6 and a
second peak in adults over age 60.
●● What genetic condition increases the risk of ALL?
Answer: A: Down syndrome.
●● What other genetic conditions increase the risk of ALL?
Answer: A: Neurofibromatosis type 1, Bloom syndrome, and ataxia
telangiectasia.
●● Q: Which is a risk factor for developing ALL?
A. Having the Philadelphia chromosome
B. Having a history of asthma
C. Having iron deficiency anemia
D. Having prior exposure to high levels of environmental radiation
EXAMINATION TEST COMPLETE
QUESTIONS AND SOLUTIONS
●● What happens when abnormal white blood cells are produced in
ALL?
Answer: The body cannot fight infection.
●● What does the bone marrow make?
Answer: Immature cells known as blood stem cells.
●● What can a blood stem cell become?
Answer: Either a lymphoid stem cell or a myeloid stem cell.
●● What does a lymphoid stem cell become?
Answer: A lymphoblast, which turns into a white blood cell.
●● What are the three types of cells that lymphoblasts can become?
Answer: B lymphocytes, T lymphocytes, or natural killer cells.
●● What do B lymphocytes do?
Answer: Fight infection and make antibodies.
,●● What do T lymphocytes do?
Answer: Help the B lymphocytes.
●● What do natural killer cells do?
Answer: Attack viruses and cancer cells.
●● Flashcard 10Q: What happens in ALL?
Answer: A: The bone marrow makes more lymphocytes than needed.
●● What happens when too many B or T lymphocytes are produced?
Answer: A: They increase in the blood and bone marrow, causing
healthy WBCs, RBCs, and platelets to be outnumbered.
●● What is the etiology of ALL?
Answer: A: Unknown.
●● What environmental factors may be associated with ALL?
Answer: A: Ionizing radiation, benzene, and previous exposure to
radiotherapy or chemotherapy.
●● What is a risk factor for developing ALL?
Answer: A: Prior exposure to ionizing radiation.
, ●● What types of radiation exposure can increase the risk of ALL?
Answer: A: Therapeutic radiation or radiation from nuclear accidents.
●● What previous treatment increases the risk of ALL?
Answer: A: A history of chemotherapy.
●● What is the incidence pattern of ALL?
Answer: A: Bimodal, with a primary peak in children under age 6 and a
second peak in adults over age 60.
●● What genetic condition increases the risk of ALL?
Answer: A: Down syndrome.
●● What other genetic conditions increase the risk of ALL?
Answer: A: Neurofibromatosis type 1, Bloom syndrome, and ataxia
telangiectasia.
●● Q: Which is a risk factor for developing ALL?
A. Having the Philadelphia chromosome
B. Having a history of asthma
C. Having iron deficiency anemia
D. Having prior exposure to high levels of environmental radiation
