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  • DIABETES MELLITUS- PART 1
  • DIABETES MELLITUS- PART 1
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Diabetes Mellitus – Part 1 Study Guide & Exam Review

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Review Diabetes Mellitus – Part 1 with a focused study resource covering foundational concepts related to diabetes and its management. This material supports understanding diabetes mellitus, important disease concepts, clinical manifestations, assessment, diagnosis, treatment principles, blood glucose management, and patient care considerations. Ideal for nursing and healthcare students preparing for exams, coursework, clinical practice, and comprehensive review of diabetes mellitus concepts

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9/13/26, 5:25 AM DIABETES MELLITUS- PART 1 Flashcards | Quizlet



Etiology of type 1 DM Immune mediated
-Autoimmune markers: chromosome 6
-HLA: DR3 & DR4 MHC genes


Idiopathic
-without autoimmune markers or HLA association
Moleuclar mimicry of vriruses


Etiology of type 2 DM Environmental factors: Sedentary lifestyle.
•Dietary habits
•central obesity
•first-degree relatives have 5- to 10-fold higher risk


Metabolic defect in type 2 DM •Insulin resistance
Β-cell dysfunction


Cause of insulin resistance in diabetes •Non-esterified free fatty acids
•Adipokines
•Chronic inflammation in adipose tissue


How inflammation in obesity causes insulin resistance •Excess FFAs within macrophages and cells activate the Inflammasome (a
multiprotein cytoplasmic complex) and secret cytokine interleukin IL-1 & •additional
proinflammatory cytokines. Act on the major sites of insulin action and produce
insulin resistance


Classical triad of DM 1. Polydipsia
2. Polyphagia
3. Polyuria.




https://quizlet.com/in/976916532/diabetes-mellitus-part-1-flash-cards/?funnelUUID=98cb53be-8272-4210-8e77-823bf2f09907 4/5

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