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HESI RN Exit Exam V3 with NGN 2027/2028 | 135+ Practice Questions with Answers & Detailed Rationales | Comprehensive RN Exit Exam Prep

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Prepare for the HESI RN Exit Exam with a comprehensive practice resource covering key nursing concepts and Next Generation NCLEX (NGN)-style clinical judgment. This study material includes 135+ practice questions, answer keys, and detailed rationales designed to reinforce nursing knowledge, prioritization, delegation, patient safety, pharmacology, and clinical decision-making. Ideal for nursing students preparing for the RN exit examination and transitioning toward NCLEX-RN preparation. Use the questions and rationales to identify knowledge gaps, strengthen test-taking skills, and review high-yield nursing concepts.

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HESI RN Exit Exam V3 with NGN 2027/2028 |
Actual Questions & Verified Answers with
Detailed Rationales | 135+ Questions | Pass
Guaranteed – A+ Graded

Description


Prepare confidently for the HESI RN Exit Exam V3 with this complete, updated study
guide featuring NGN-style questions and verified rationalized answers .

This resource includes challenging practice questions aligned with the latest NCLEX-RN
test plan, helping you master clinical judgment and boost exam readiness . It covers all core
content areas tested on the exam, with detailed explanations for both correct and incorrect
options to reinforce critical thinking .

Key content areas covered:

 Medical-Surgical Nursing – Cardiovascular, respiratory, neurological, renal, and endocrine
disorders
 Pharmacology – Drug classifications, adverse effects, interactions, and nursing
considerations
 Maternal-Newborn & Pediatrics – Prenatal care, labor and delivery, postpartum, and
growth/development
 Mental Health – Psychiatric disorders, therapeutic communication, and
psychopharmacology

, Leadership & Management – Delegation, prioritization, ethics, and quality improvement




Section 1: Medical-Surgical Nursing (Questions 1-80)

1. A patient with heart failure is prescribed furosemide (Lasix). Which laboratory value
should the nurse monitor most closely?

 A) Serum sodium
 B) Serum potassium
 C) Serum calcium
 D) Serum magnesium

Correct Answer: B

Rationale: Furosemide is a loop diuretic that causes potassium wasting, leading to
hypokalemia, which increases the risk of digoxin toxicity and arrhythmias .




2. A patient with chronic obstructive pulmonary disease (COPD) has a PaCO2 of 68
mmHg and an SpO2 of 88% on room air. The nurse should administer oxygen at:

 A) 2 L/min via nasal cannula

, B) 4 L/min via nasal cannula
 C) 6 L/min via simple mask
 D) 10 L/min via non-rebreather mask

Correct Answer: A

Rationale: COPD patients with chronic hypercapnia rely on hypoxic drive; high oxygen can
suppress respiratory drive. Target SpO2 is 88-92%, starting at 1-2 L/min .




3. A patient with type 1 diabetes mellitus is found unconscious. The blood glucose
reading is 45 mg/dL. The nurse should first:

 A) Administer 50% dextrose IV push
 B) Give 15 grams of oral carbohydrate
 C) Administer glucagon IM
 D) Recheck blood glucose in 15 minutes

Correct Answer: A

Rationale: An unconscious patient cannot swallow safely; IV dextrose is the priority. Glucagon
IM is used if no IV access is available .




4. Which finding in a patient with a new cast on the lower leg is most concerning for
compartment syndrome?

 A) Pain that is relieved by elevation

,  B) Toes that are pink and warm
 C) Pain that worsens with passive extension of the toes
 D) Mild swelling around the cast edges

Correct Answer: C

Rationale: Pain out of proportion to injury that worsens with passive stretch is an early sign of
compartment syndrome .




5. A patient with peptic ulcer disease is prescribed omeprazole (Prilosec). The nurse
should instruct the patient to take this medication:

 A) With meals
 B) 30-60 minutes before breakfast
 C) At bedtime with a snack
 D) With antacids

Correct Answer: B

Rationale: Proton pump inhibitors like omeprazole are most effective when taken 30-60
minutes before the first meal of the day, allowing the medication to inhibit the proton pumps
activated by eating .




6. A patient with a traumatic brain injury has an intracranial pressure (ICP) of 22 mmHg.
The nurse should:

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