NR566 COMPREHENSIVE EXAMINATION
TEST 2026 QUESTIONS AND SOLUTIONS
GRADED A+
◉ Selective Estrogen Receptor Modulators (SERMs).
Answer: Tamoxifen, toremifene, raloxifene -- provide estrogen
benefits while avoiding its drawbacks
◉ Dysfunctional uterine bleeding.
Answer: 10-14 day course of progestin
◉ Amenorrhea treatment.
Answer: progestin helps induce menstrual flow
◉ Amenorrhea estrogen levels are low.
Answer: give progestin for 5-10 days
◉ Long term progestin therapy.
Answer: protection against endometrial cancer
,◉ Estradiol.
Answer: most active estrogenic compound. oral estrogen option
◉ Advantages of estrogen transdermal patch.
Answer: lower total estrogen dose. less n/v. less fluctuation of
estrogen blood levels. lower r/f DVT, PE and stroke
◉ Femring.
Answer: intravaginal ring controls hot flashes and night sweats.
Treats vulval and vaginal atrophy
◉ No gap method of changing from one OC to another.
Answer: go straight from one type of OC to the other without taking
a gap.
◉ initiating OC treatment.
Answer: first day of menstrual cycle (no backup BC needed) OR first
sunday after onset of menses (backup BC needed for 7 days)
◉ Initiating androgen therapy short term.
Answer: delayed sexual maturation causing a boy significant
distress. Limited course of Fluoxymesterone and methyltestosterone
are approved.
, ◉ androgen therapy long term.
Answer: if delayed puberty is the result of true hypogonadism
◉ role of androgens in anemia.
Answer: promote synthesis of erythropoietin the renal hormone that
stimulates production of RBCs
◉ Alprostadil preferred administration.
Answer: direct injection into the corpus cavernosum. Rapid
response
◉ Finasteride.
Answer: BPH tx 5a reductase inhibitor. Causes prostate to shrink.
benefits take months
◉ Tamsulosin.
Answer: BPH tx alpha adrenergic antagonist. relaxes smooth muscle.
benefits are rapid
◉ Adverse effects of silodosin and tamsulosin.
Answer: r/f floppy iris syndrome during cataract surgery.
TEST 2026 QUESTIONS AND SOLUTIONS
GRADED A+
◉ Selective Estrogen Receptor Modulators (SERMs).
Answer: Tamoxifen, toremifene, raloxifene -- provide estrogen
benefits while avoiding its drawbacks
◉ Dysfunctional uterine bleeding.
Answer: 10-14 day course of progestin
◉ Amenorrhea treatment.
Answer: progestin helps induce menstrual flow
◉ Amenorrhea estrogen levels are low.
Answer: give progestin for 5-10 days
◉ Long term progestin therapy.
Answer: protection against endometrial cancer
,◉ Estradiol.
Answer: most active estrogenic compound. oral estrogen option
◉ Advantages of estrogen transdermal patch.
Answer: lower total estrogen dose. less n/v. less fluctuation of
estrogen blood levels. lower r/f DVT, PE and stroke
◉ Femring.
Answer: intravaginal ring controls hot flashes and night sweats.
Treats vulval and vaginal atrophy
◉ No gap method of changing from one OC to another.
Answer: go straight from one type of OC to the other without taking
a gap.
◉ initiating OC treatment.
Answer: first day of menstrual cycle (no backup BC needed) OR first
sunday after onset of menses (backup BC needed for 7 days)
◉ Initiating androgen therapy short term.
Answer: delayed sexual maturation causing a boy significant
distress. Limited course of Fluoxymesterone and methyltestosterone
are approved.
, ◉ androgen therapy long term.
Answer: if delayed puberty is the result of true hypogonadism
◉ role of androgens in anemia.
Answer: promote synthesis of erythropoietin the renal hormone that
stimulates production of RBCs
◉ Alprostadil preferred administration.
Answer: direct injection into the corpus cavernosum. Rapid
response
◉ Finasteride.
Answer: BPH tx 5a reductase inhibitor. Causes prostate to shrink.
benefits take months
◉ Tamsulosin.
Answer: BPH tx alpha adrenergic antagonist. relaxes smooth muscle.
benefits are rapid
◉ Adverse effects of silodosin and tamsulosin.
Answer: r/f floppy iris syndrome during cataract surgery.
