NR566 CERTIFICATION EVALUATION 2026
EXAM QUESTIONS AND SOLUTIONS
◉ Pyrantel Pamoate MOA.
Answer: depolarizing neuromuscular blocking agent that causes
spastic paralysis of intestinal parasites
◉ Pyrantel Pamoate High Risk Patients.
Answer: Patients with cardiac disease, liver impairment, or seizure
disorders are at increased risk for complications.
◉ Pyrantel Pamoate Adverse Events.
Answer: Neonates given formulations with benzyl alcohol or its
derivatives had developed a potentially fatal "gasping syndrome"
◉ Abendazole/Ivermectin/Mebendazole and Preganancy.
Answer: Antihelmetic drugs contraindicated in pregnancy
◉ Enterobiasis (pinworm) Treatment.
Answer: Most common helminthic infection in United States;
Treatment of choice: Mebendazole or Pyrantel Pamoate
,◉ Invermectin/Moxidectin High Risk Patients.
Answer: Patients with hypotension or taking antihypertensive drugs
may be at risk for increased hypotension and falls.
◉ Invermectin MOA.
Answer: disrupts nerve traffic and muscle function in target
parasites by opening chloride channels on the cell surface, which
allows chloride ions to rush into nerve and muscle cells. The
resultant hyperpolarization of these cells causes paralysis followed
by death.
◉ Invermectin Adverse Events.
Answer: may cause Mazzotti reaction (allergic and inflammatory
response to the death of O. volvulus rather than a reaction to the
drug. Includes pruritus, rash, fever, lymph node tenderness, and
bone and joint pain.
◉ Invermectin Therapeutic Use.
Answer: Onchocerciasis (River Blindness)
◉ Praziquantel MOA.
Answer: low therapeutic concentrations, the drug produces spastic
paralysis, causing detachment of worms from body tissues. At high
therapeutic concentrations, praziquantel disrupts the integument of
, the worms, rendering the parasites vulnerable to lethal attack by
host defenses.
◉ Praziquantel Adverse Events.
Answer: Transient headache and abdominal discomfort are the most
frequent reactions for this anthelmintic
◉ Moxidectin Adverse Events.
Answer: AE to this antihelmintic include flu-like symptoms of the
Mazotti-response associated with death of the microfilariae during
the first week. Adverse effects mirror those of ivermectin.
◉ Albendazole Baseline Data.
Answer: Baseline Data for this antihelmintic include(liver function
and complete blood count [CBC] with differential);
◉ Albendazole Monitoring.
Answer: Monitoring of this antihelmintic inlcude (liver function and
CBC with differential);
◉ Mebendazaole Baseline Data.
Answer: Baseline Data for this antihelmintic include(liver function,
CBC with differential, and renal function);
EXAM QUESTIONS AND SOLUTIONS
◉ Pyrantel Pamoate MOA.
Answer: depolarizing neuromuscular blocking agent that causes
spastic paralysis of intestinal parasites
◉ Pyrantel Pamoate High Risk Patients.
Answer: Patients with cardiac disease, liver impairment, or seizure
disorders are at increased risk for complications.
◉ Pyrantel Pamoate Adverse Events.
Answer: Neonates given formulations with benzyl alcohol or its
derivatives had developed a potentially fatal "gasping syndrome"
◉ Abendazole/Ivermectin/Mebendazole and Preganancy.
Answer: Antihelmetic drugs contraindicated in pregnancy
◉ Enterobiasis (pinworm) Treatment.
Answer: Most common helminthic infection in United States;
Treatment of choice: Mebendazole or Pyrantel Pamoate
,◉ Invermectin/Moxidectin High Risk Patients.
Answer: Patients with hypotension or taking antihypertensive drugs
may be at risk for increased hypotension and falls.
◉ Invermectin MOA.
Answer: disrupts nerve traffic and muscle function in target
parasites by opening chloride channels on the cell surface, which
allows chloride ions to rush into nerve and muscle cells. The
resultant hyperpolarization of these cells causes paralysis followed
by death.
◉ Invermectin Adverse Events.
Answer: may cause Mazzotti reaction (allergic and inflammatory
response to the death of O. volvulus rather than a reaction to the
drug. Includes pruritus, rash, fever, lymph node tenderness, and
bone and joint pain.
◉ Invermectin Therapeutic Use.
Answer: Onchocerciasis (River Blindness)
◉ Praziquantel MOA.
Answer: low therapeutic concentrations, the drug produces spastic
paralysis, causing detachment of worms from body tissues. At high
therapeutic concentrations, praziquantel disrupts the integument of
, the worms, rendering the parasites vulnerable to lethal attack by
host defenses.
◉ Praziquantel Adverse Events.
Answer: Transient headache and abdominal discomfort are the most
frequent reactions for this anthelmintic
◉ Moxidectin Adverse Events.
Answer: AE to this antihelmintic include flu-like symptoms of the
Mazotti-response associated with death of the microfilariae during
the first week. Adverse effects mirror those of ivermectin.
◉ Albendazole Baseline Data.
Answer: Baseline Data for this antihelmintic include(liver function
and complete blood count [CBC] with differential);
◉ Albendazole Monitoring.
Answer: Monitoring of this antihelmintic inlcude (liver function and
CBC with differential);
◉ Mebendazaole Baseline Data.
Answer: Baseline Data for this antihelmintic include(liver function,
CBC with differential, and renal function);
