NR546 FINAL CERTIFICATION
EVALUATION PRACTICE SOLUTION
TESTED QUESTIONS WITH COMPLETE
ANSWERS
●● SSRI with highest risk of discontinuation syndrome
Answer: Paroxetine.
●● Neurotransmitters in monoamine hypothesis of depression
Answer: Serotonin, norepinephrine, and dopamine.
●● Safest SSRI in polypharmacy and elderly
Answer: Escitalopram.
●● Class of antidepressant requiring dietary tyramine restriction
Answer: MAOIs.
●● Hallmark symptom of serotonin syndrome
Answer: Hyperreflexia and clonus.
●● Opioid withdrawal medication with ceiling effect
,Answer: Buprenorphine.
●● Medication contraindicated in eating disorders
Answer: Bupropion.
●● Antidepressant associated with priapism
Answer: Trazodone.
●● Most activating SSRI that may worsen anxiety
Answer: Fluoxetine.
●● Medication class best avoided in elderly
Answer: Benzodiazepines.
●● Mechanism of action of memantine
Answer: NMDA receptor antagonist.
●● Dementia medication derived from daffodils
Answer: Galantamine.
●● Brain region essential for memory formation
Answer: Hippocampus.
, ●● Unique risk of lamotrigine therapy
Answer: Stevens-Johnson syndrome.
●● First-line medication for restless legs syndrome
Answer: Ropinirole.
●● MOA of atomoxetine for ADHD
Answer: Norepinephrine reuptake inhibition.
●● Preferred ADHD medication for patients with substance use history
Answer: Atomoxetine.
●● Major side effect of donepezil
Answer: GI distress (nausea, diarrhea).
●● Biomarker elevated in Alzheimer's disease tangles
Answer: Tau protein.
●● Key counseling point for cholinesterase inhibitors
Answer: Start low and increase slowly to minimize GI upset.
EVALUATION PRACTICE SOLUTION
TESTED QUESTIONS WITH COMPLETE
ANSWERS
●● SSRI with highest risk of discontinuation syndrome
Answer: Paroxetine.
●● Neurotransmitters in monoamine hypothesis of depression
Answer: Serotonin, norepinephrine, and dopamine.
●● Safest SSRI in polypharmacy and elderly
Answer: Escitalopram.
●● Class of antidepressant requiring dietary tyramine restriction
Answer: MAOIs.
●● Hallmark symptom of serotonin syndrome
Answer: Hyperreflexia and clonus.
●● Opioid withdrawal medication with ceiling effect
,Answer: Buprenorphine.
●● Medication contraindicated in eating disorders
Answer: Bupropion.
●● Antidepressant associated with priapism
Answer: Trazodone.
●● Most activating SSRI that may worsen anxiety
Answer: Fluoxetine.
●● Medication class best avoided in elderly
Answer: Benzodiazepines.
●● Mechanism of action of memantine
Answer: NMDA receptor antagonist.
●● Dementia medication derived from daffodils
Answer: Galantamine.
●● Brain region essential for memory formation
Answer: Hippocampus.
, ●● Unique risk of lamotrigine therapy
Answer: Stevens-Johnson syndrome.
●● First-line medication for restless legs syndrome
Answer: Ropinirole.
●● MOA of atomoxetine for ADHD
Answer: Norepinephrine reuptake inhibition.
●● Preferred ADHD medication for patients with substance use history
Answer: Atomoxetine.
●● Major side effect of donepezil
Answer: GI distress (nausea, diarrhea).
●● Biomarker elevated in Alzheimer's disease tangles
Answer: Tau protein.
●● Key counseling point for cholinesterase inhibitors
Answer: Start low and increase slowly to minimize GI upset.
