2026/2027 Comprehensive Practice Questions &
WELL VERIFIED ANSWERS
... All Major Topics
**Format:** Single-best-answer
**Level:** Family medicine / board-review
**Important:** Original practice questions, not recalled or leaked ABFM examination items.
. SECTION 1 — DIAGNOSIS AND SCREENING
... 1. Which HbA1c value is diagnostic of diabetes mellitus in an asymptomatic adult when
appropriately confirmed?
A. 5.4%
B. 5.7%
C. 6.0%
D. 6.5%
**Answer: D — 6.5%**
,**Rationale:** An HbA1c of ≥6.5% is one of the accepted diagnostic criteria for diabetes. In an
asymptomatic patient, confirmation with repeat testing or another diagnostic test is generally
required.
---
... 2. Which fasting plasma glucose is diagnostic of diabetes?
A. 99 mg/dL
B. 110 mg/dL
C. 126 mg/dL
D. 140 mg/dL
**Answer: C — 126 mg/dL**
**Rationale:** Diabetes is diagnosed with fasting plasma glucose ≥126 mg/dL, with appropriate
confirmation when the patient is asymptomatic.
---
... 3. A patient has a 2-hour plasma glucose of 200 mg/dL during a 75-g oral glucose tolerance
test. This result is:
A. Normal
B. Prediabetes
C. Diagnostic of diabetes
D. Diagnostic only if fasting glucose is elevated
,**Answer: C**
---
... 4. Which HbA1c range is consistent with prediabetes?
A. 4.0–5.0%
B. 5.0–5.6%
C. 5.7–6.4%
D. 6.5–7.0%
**Answer: C**
---
... 5. Which patient is at increased risk for type 2 diabetes?
A. Patient with obesity and a first-degree relative with diabetes
B. Patient with normal BMI and no risk factors
C. Patient with isolated seasonal allergies
D. Patient with myopia
**Answer: A**
---
, ... 6. A patient has polyuria, polydipsia, weight loss, and a random plasma glucose of 245 mg/dL.
What is the most appropriate interpretation?
A. Normal glucose tolerance
B. Prediabetes
C. Diabetes mellitus
D. Reactive hypoglycemia
**Answer: C**
---
... 7. Which condition can make HbA1c less reliable?
A. Normal red-cell lifespan
B. Certain hemoglobinopathies
C. Normal renal function
D. Normal iron status
**Answer: B**
---
... 8. Which test is particularly useful when the diagnosis of diabetes type is uncertain?