TOP 50 DRUGS- ATI PHARM EXAM LATEST 2026 UPDATED
QUESTIONS AND VERIFIED 100% SOLUTIONS (2026/2027)
GRADE: A+|STATUS: GUARANTEED PASS
Atorvastatin - Answers -Lipid-Lowering agent
Therapeutic Effects: Decrease LDL/VLDL/Triglycer.; Increase HDL (slightly)
A/R: RHABDOMYOLYSIS (muscle cell lysis), toxins into circulation, rashes, constipation, flatus, GI
effects
Avoid grapefruit & grapefruit juice. With unexplained muscle pain/tenderness-monitor CPK -- if
it increases, d/c med = life threatening. Check LFTs
Enoxaparin - Answers -Anticoagulant
Causes the inhibitory effect of anti-thrombin on factor Xa and thrombin
Therapeutic Effects: Prevention of DVT/PE.
Antidote = protamine sulfate
A/R: Bleeding, anemia, thrombocytopenia, erythema at injection site, pain. Use only 1 heparin
product at a time
Assess for bleeding, CBC, platelet count, neurological impairment. Note pkg info for prefilled
syringe- keep air lock. NO aspiration or massage. High Alert Medication
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,Glyburide - Answers -Antidiabetic (Sulfonylurea)
Therapeutic Effects: Stimulates release of insulin from the pancreas, increase receptor site
sensitivity
A/R: Photosensitivity, low bg, aplastic ANEMIA
Observe s/s of hypoglycemia. High Alert Medication. Do not take glyburide if you are unable to
eat. Avoid alcohol.
Morphine sulfate - Answers -Opioid analgesic (agonist)
Therapeutic Effects: Decrease pain, pulmonary edema, pain with MI
A/R: Respiratory depression, confusion, sedation, low BP, constipation
Typical opioid precautions. Dilute for IV push. Give over 4-5 minutes
Gabapentin - Answers -Analgesic adjunct/ Anticonvulsant.
Therapeutic Effects: Decrease seizures, neuralgias, chronic pain
A/R: Drowsiness, ataxia. Avoid in pregnancy/breastfeeding
TID dosing should not exceed 12 hr between doses.
Do not D/C abruptly; do not take within 2hr of antacid. avoid driving-till MD OK; Avoid use with
other CNS depressants
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, Esomeprazole - Answers -Antiulcer agents (proton pump inhibitors)
Therapeutic Effects: Decrease acid accumulation in the gastric lumen which decreases GI reflex
Healing of duodenal ulcers
A/R: Headache, constipation, dry mouth, GI effects
Give 1hr before meals
Do not crush or chew pellets Assess for epigastric/abdominal pain, blood in stool, emesis, or
gastric aspirate Give slow IVP over 5-6 minutes, diluted with 0.9% NS
Nitroglycerin - Answers -Antianginal, Nitrate
Therapeutic Effects: Increases coronary blood flow to decrease angina attacks. Decrease BP.
Increase cardiac output.
A/R: Dizziness. HA. Blurred Vision. Low BP, High HR, Flushing, GI effects.
Tablets should be kept in original container & cotton should be removed. Do not open bottle
frequently or handle tablets. Replace q 6 months after opening
Transderm Nitro, nitroglycerin - Answers -Antianginal
Therapeutic Effects: Relief or prevention of anginal attacks; increase cardiac output; decrease
blood pressure
Adverse Reactions & side effects: dizziness, headache, restlessness, syncope, hypotension,
contact dermatitis, blurred vision
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QUESTIONS AND VERIFIED 100% SOLUTIONS (2026/2027)
GRADE: A+|STATUS: GUARANTEED PASS
Atorvastatin - Answers -Lipid-Lowering agent
Therapeutic Effects: Decrease LDL/VLDL/Triglycer.; Increase HDL (slightly)
A/R: RHABDOMYOLYSIS (muscle cell lysis), toxins into circulation, rashes, constipation, flatus, GI
effects
Avoid grapefruit & grapefruit juice. With unexplained muscle pain/tenderness-monitor CPK -- if
it increases, d/c med = life threatening. Check LFTs
Enoxaparin - Answers -Anticoagulant
Causes the inhibitory effect of anti-thrombin on factor Xa and thrombin
Therapeutic Effects: Prevention of DVT/PE.
Antidote = protamine sulfate
A/R: Bleeding, anemia, thrombocytopenia, erythema at injection site, pain. Use only 1 heparin
product at a time
Assess for bleeding, CBC, platelet count, neurological impairment. Note pkg info for prefilled
syringe- keep air lock. NO aspiration or massage. High Alert Medication
1|Page
,Glyburide - Answers -Antidiabetic (Sulfonylurea)
Therapeutic Effects: Stimulates release of insulin from the pancreas, increase receptor site
sensitivity
A/R: Photosensitivity, low bg, aplastic ANEMIA
Observe s/s of hypoglycemia. High Alert Medication. Do not take glyburide if you are unable to
eat. Avoid alcohol.
Morphine sulfate - Answers -Opioid analgesic (agonist)
Therapeutic Effects: Decrease pain, pulmonary edema, pain with MI
A/R: Respiratory depression, confusion, sedation, low BP, constipation
Typical opioid precautions. Dilute for IV push. Give over 4-5 minutes
Gabapentin - Answers -Analgesic adjunct/ Anticonvulsant.
Therapeutic Effects: Decrease seizures, neuralgias, chronic pain
A/R: Drowsiness, ataxia. Avoid in pregnancy/breastfeeding
TID dosing should not exceed 12 hr between doses.
Do not D/C abruptly; do not take within 2hr of antacid. avoid driving-till MD OK; Avoid use with
other CNS depressants
2|Page
, Esomeprazole - Answers -Antiulcer agents (proton pump inhibitors)
Therapeutic Effects: Decrease acid accumulation in the gastric lumen which decreases GI reflex
Healing of duodenal ulcers
A/R: Headache, constipation, dry mouth, GI effects
Give 1hr before meals
Do not crush or chew pellets Assess for epigastric/abdominal pain, blood in stool, emesis, or
gastric aspirate Give slow IVP over 5-6 minutes, diluted with 0.9% NS
Nitroglycerin - Answers -Antianginal, Nitrate
Therapeutic Effects: Increases coronary blood flow to decrease angina attacks. Decrease BP.
Increase cardiac output.
A/R: Dizziness. HA. Blurred Vision. Low BP, High HR, Flushing, GI effects.
Tablets should be kept in original container & cotton should be removed. Do not open bottle
frequently or handle tablets. Replace q 6 months after opening
Transderm Nitro, nitroglycerin - Answers -Antianginal
Therapeutic Effects: Relief or prevention of anginal attacks; increase cardiac output; decrease
blood pressure
Adverse Reactions & side effects: dizziness, headache, restlessness, syncope, hypotension,
contact dermatitis, blurred vision
3|Page
