BIOL 133 (15) Questions with CORRECT Answers
Question:
___ is the first protein to bind to mRNA to being initiation of translation.
Answer:
TFIIA B. eIF-2 C. TFIID D. 60S ribosomal subunit E. 40S ribosomal subunit
Question:
What part of the ribosome is important in catalyzing peptide bonds?
Answer:
the rRNA B. the ribosomal proteins C. the E site D. the methyl guanosine Cap
Question:
In eukaryotes, where would a protective modification be found on mRNA?
Answer:
on the 5' end B. on the 3' end C. on both the 5' end and the 3' end D. on neither
the 5' end nor the 3' end
Question:
Epigenetics refers to a special kind of hereditary mechanism. Epigenetic changes
do not change the DNA nucleotide sequence, yet their effect on gene expression can
last for several generations. In one surprising study, it was found that the
grandsons of men who suffered suffered a famine were less likely to die of
cardiovascular disease. The experience of famine made some cardioprotective change
in the sperm of those grandfathers that was passed on. What type of change was
likely responsible?
Answer:
histone acetylation of DNA methylation B. ubiquitin tagging C. phosphatase levels
D. transcription factor activity
Question:
Overexpression of miRNAs can lead to a decrease of protein expression associated
with some forms of cancer. What could a drug do to counter this effect?
Answer:
increase promoter activity of the miRNA genes B. decrease expression of RNA
polymerase C. increase expression of RISC D. decrease expression of miRNA
, Question:
A gene is made up of three exons (numbered consecutively) with two introns (intron
1 between exons 1 and 2 and intron 2 between exons 2 and 3). What would happen if
there were a mutation at the 3' splice site of intron 1?
Answer:
mRNA with all three exons and both introns B. mRNA with only exons 2 and 3 C. mRNA
with all three exons along with intron 1 D. mRNA with exons 2 and 3 along with
intron 2
Question:
Isolating all of the RNA out of an organism, subjecting it to reverse
transcriptase, and then cloning all of the resulting DNA into plasmids is the
process of creating.
Answer:
genomic libraries B. cytogenetic maps C. cDNA libraries D. expresses sequence tags
Question:
___ hotspots can decrease the accuracy of linkage maps.
Answer:
Variable B. Microsatellite C. Recombination D. Cytogenetic E. Physical
Question:
In order to focus on only the expressed portions of DNA, what type of sequencing
can be used?
Answer:
pairwiseend sequencing B. wholegenome sequencing C. shotgun sequencing D.
wholeexome sequencing
Question:
Before cellular DNA can be subjected to gel electrophoresis, what needs to happen?
Answer:
degraded and combined B. amplified and acidified C. modified and cleaned D.
released and isolated
Question:
___ is the first protein to bind to mRNA to being initiation of translation.
Answer:
TFIIA B. eIF-2 C. TFIID D. 60S ribosomal subunit E. 40S ribosomal subunit
Question:
What part of the ribosome is important in catalyzing peptide bonds?
Answer:
the rRNA B. the ribosomal proteins C. the E site D. the methyl guanosine Cap
Question:
In eukaryotes, where would a protective modification be found on mRNA?
Answer:
on the 5' end B. on the 3' end C. on both the 5' end and the 3' end D. on neither
the 5' end nor the 3' end
Question:
Epigenetics refers to a special kind of hereditary mechanism. Epigenetic changes
do not change the DNA nucleotide sequence, yet their effect on gene expression can
last for several generations. In one surprising study, it was found that the
grandsons of men who suffered suffered a famine were less likely to die of
cardiovascular disease. The experience of famine made some cardioprotective change
in the sperm of those grandfathers that was passed on. What type of change was
likely responsible?
Answer:
histone acetylation of DNA methylation B. ubiquitin tagging C. phosphatase levels
D. transcription factor activity
Question:
Overexpression of miRNAs can lead to a decrease of protein expression associated
with some forms of cancer. What could a drug do to counter this effect?
Answer:
increase promoter activity of the miRNA genes B. decrease expression of RNA
polymerase C. increase expression of RISC D. decrease expression of miRNA
, Question:
A gene is made up of three exons (numbered consecutively) with two introns (intron
1 between exons 1 and 2 and intron 2 between exons 2 and 3). What would happen if
there were a mutation at the 3' splice site of intron 1?
Answer:
mRNA with all three exons and both introns B. mRNA with only exons 2 and 3 C. mRNA
with all three exons along with intron 1 D. mRNA with exons 2 and 3 along with
intron 2
Question:
Isolating all of the RNA out of an organism, subjecting it to reverse
transcriptase, and then cloning all of the resulting DNA into plasmids is the
process of creating.
Answer:
genomic libraries B. cytogenetic maps C. cDNA libraries D. expresses sequence tags
Question:
___ hotspots can decrease the accuracy of linkage maps.
Answer:
Variable B. Microsatellite C. Recombination D. Cytogenetic E. Physical
Question:
In order to focus on only the expressed portions of DNA, what type of sequencing
can be used?
Answer:
pairwiseend sequencing B. wholegenome sequencing C. shotgun sequencing D.
wholeexome sequencing
Question:
Before cellular DNA can be subjected to gel electrophoresis, what needs to happen?
Answer:
degraded and combined B. amplified and acidified C. modified and cleaned D.
released and isolated
