NURS 617 PHARM EXAM 1 EXAM PREP
SOLVED QUESTIONS ACCURATE ANSWERS
PREMIUM REVIEW
◉ Pharmacokinetics
Answer: The process by which drugs are absorbed, distributed
within the body, metabolized, and excreted.
◉ Pharmacogenomics
Answer: The study of the influence of genetic factors on drug
response that result in the absence, overabundance, or insufficiency
of drug-metabolizing enzymes
◉ Medication side effect
Answer: a nearly unavoidable secondary effect of a drug produced at
therapeutic doses which is generally predictable and with an
intensity that is dose-dependent
◉ Adverse Effect
Answer: A drug-induced, secondary effect of a drug that produces a
change in a patients condition that is noxious, harmful or
unpleasant, which requires treatment or reduction or
,discontinuation of the drug and which usually occurs at therapeutic
doses.
◉ Type A adverse drug reactions
Answer: exaggerated, but otherwise expected pharmacological effect
of a drug -> predictable and dose dependent -> ex. toxicity of
overdose, side effects, secondary effects, drug interactions
◉ Type B adverse drug reactions
Answer: idiosyncratic effects (not expected) -> dose independent
and unpredictable -> intolerance, hypersensitivity, pseudo allergic,
idiosyncratic
◉ Drug tolerance
Answer: the tendency for larger doses of a drug to be required over
time to achieve the same effect
◉ Physical drug dependence
Answer: condition where a person's body becomes unable to
function normally without a particular drug
◉ Psychological dependence
Answer: a condition in which a person believes that a drug is needed
in order to feel good or to function normally
,◉ Allergic reaction
Answer: An immunologic hypersensitivity reaction resulting from
the unusual sensitivity of a patient to a particular medication; a type
of adverse drug event.
◉ Idiosyncratic or paradoxical reaction
Answer: When a drug may cause a totally unexpected and often
opposite effect in a few patients
◉ Carcinogenic reaction
Answer: medications and environmental chemicals that are thought
to cause cancer
◉ Teratogenic reaction
Answer: Refers to the drug induced damage that develops in the
fetus
◉ Beneficial potentiative drug-drug interaction
Answer: Aspirin and Codeine are both analgesic drugs and when
administered concurrently the combo provides better pain relief
than either one alone. What type of drug interaction is this?
◉ Beneficial Potentiative Drug-Drug Interaction
, Answer: Use of Beta Blockers and Diuretics together for
hypertension will provide better control blood pressure. What type
of drug interaction is this?
◉ Harmful potentiative Drug-Drug interaction
Answer: Use of diazepam together with Morphine will have additive
CNS depression and could lead to respiratory distress. What type of
drug interaction is this?
◉ Harmful potentiative Drug-Drug interaction
Answer: Concurrent use of aspirin with Coumadin will significantly
increase each others inhibitory effects on blood coagulation,
resulting in an increase risk for bleeding. What type of drug
interaction is this?
◉ Beneficial inhibitory drug interaction
Answer: Use of Naloxone after an overdose of Meperidine is an
example of what type of drug interaction?
◉ Beneficial inhibitory drug interaction
Answer: Giving Protamine when there is excessive bleeding from
overdose of Heparin is an example of what type of drug interaction?
◉ Harmful inhibitory drug interaction
SOLVED QUESTIONS ACCURATE ANSWERS
PREMIUM REVIEW
◉ Pharmacokinetics
Answer: The process by which drugs are absorbed, distributed
within the body, metabolized, and excreted.
◉ Pharmacogenomics
Answer: The study of the influence of genetic factors on drug
response that result in the absence, overabundance, or insufficiency
of drug-metabolizing enzymes
◉ Medication side effect
Answer: a nearly unavoidable secondary effect of a drug produced at
therapeutic doses which is generally predictable and with an
intensity that is dose-dependent
◉ Adverse Effect
Answer: A drug-induced, secondary effect of a drug that produces a
change in a patients condition that is noxious, harmful or
unpleasant, which requires treatment or reduction or
,discontinuation of the drug and which usually occurs at therapeutic
doses.
◉ Type A adverse drug reactions
Answer: exaggerated, but otherwise expected pharmacological effect
of a drug -> predictable and dose dependent -> ex. toxicity of
overdose, side effects, secondary effects, drug interactions
◉ Type B adverse drug reactions
Answer: idiosyncratic effects (not expected) -> dose independent
and unpredictable -> intolerance, hypersensitivity, pseudo allergic,
idiosyncratic
◉ Drug tolerance
Answer: the tendency for larger doses of a drug to be required over
time to achieve the same effect
◉ Physical drug dependence
Answer: condition where a person's body becomes unable to
function normally without a particular drug
◉ Psychological dependence
Answer: a condition in which a person believes that a drug is needed
in order to feel good or to function normally
,◉ Allergic reaction
Answer: An immunologic hypersensitivity reaction resulting from
the unusual sensitivity of a patient to a particular medication; a type
of adverse drug event.
◉ Idiosyncratic or paradoxical reaction
Answer: When a drug may cause a totally unexpected and often
opposite effect in a few patients
◉ Carcinogenic reaction
Answer: medications and environmental chemicals that are thought
to cause cancer
◉ Teratogenic reaction
Answer: Refers to the drug induced damage that develops in the
fetus
◉ Beneficial potentiative drug-drug interaction
Answer: Aspirin and Codeine are both analgesic drugs and when
administered concurrently the combo provides better pain relief
than either one alone. What type of drug interaction is this?
◉ Beneficial Potentiative Drug-Drug Interaction
, Answer: Use of Beta Blockers and Diuretics together for
hypertension will provide better control blood pressure. What type
of drug interaction is this?
◉ Harmful potentiative Drug-Drug interaction
Answer: Use of diazepam together with Morphine will have additive
CNS depression and could lead to respiratory distress. What type of
drug interaction is this?
◉ Harmful potentiative Drug-Drug interaction
Answer: Concurrent use of aspirin with Coumadin will significantly
increase each others inhibitory effects on blood coagulation,
resulting in an increase risk for bleeding. What type of drug
interaction is this?
◉ Beneficial inhibitory drug interaction
Answer: Use of Naloxone after an overdose of Meperidine is an
example of what type of drug interaction?
◉ Beneficial inhibitory drug interaction
Answer: Giving Protamine when there is excessive bleeding from
overdose of Heparin is an example of what type of drug interaction?
◉ Harmful inhibitory drug interaction
