NURS 5432 Complete Exam Questions & Answers |
Comprehensive Review
Rapid progression or onset of Alzheimer's before age 80 is a red flag and the patient should be
referred to Neurology, True or False?
False
Rapid progression or onset of Alzheimer's before age 60 is a red flag
What is the First-Line medication used for Alzheimer's disease?
Cholinesterase Inhibitors
What's the MOA of the Cholinesterase Inhibitors?
Prevent the breakdown of acetylcholine, improving neurotransmissions.
What is the initial dose of Donepezil used for Alzheimer's? (What time of day)
Initial dose is 5mg at Bedtime
What is the Titration of Donepezil?
Increased to 10mg after 4-6 weeks
What is the max dose of Donepezil?
23mg/day
What is the initial dose of Galantamine?
4mg twice daily
What is the titration of Galantamine?
Extended release 8mg once daily
What is the initial dose of Rivastigmine?
The initial dose is 1.5mg
What is the dose is the dose of the transdermal patch of Rivastigmine? How often does it
need to be changed?
4.6mg changed every 24 hours
What are some side effects of Rivastigmine?
,Anorexia
Weight loss
Nausea and vomiting
Loss of appetite
Dehydration
Headaches
AV Block
What age is recommended for Elderly Patients get the Prevnar 13 Vaccination?
Age 65 and older
What age is recommended for Elderly Patients get the Pneumococcal Vaccination (PPSV23)?
Age 65 and older
What age is recommended for Elderly Patients get the Shingrix Vaccination?
Age 59 and older
How many doses are the Shingrix series?
2 doses
How many months apart should the Shingrix vaccine be given?
2-6 months apart
How often should an older adult get the influenza vaccine?
Annually (every fall)
How often should one get a Tdap Booster shot?
Booster every 10 years
Which of the follow are considered normal BMI range for older adults?
A. 20-25
B. 23-30
C. 30-45
B. 23-30
Malnutrition risk is considered > 5% weight loss in 1 month, True or False?
True
Malnutrition risk is considered > 10% weight loss in 10 months, True or False?
,False.
> 10% weight loss in 6 months
In how many second should an older adult be able to complete the Get Up and Go test?
< 12 seconds
What are the 4 main factors that alter drug distributions in older adults?
1. Increased body fat
2. Decreased lean body mass
3. Decreased body water
4. Reduced serum albumin
Fat soluble drugs accumulate in the adipose tissue leading to prolonged effects. True or False?
True
Hepatic Metabolism (Increases/Decreases) with age?
Decreases
Age Dependent Changes in Body Composition
(Inc/Dec) in body fat by 35%
(Inc/Dec) in plasma volume by 8%
(Inc/Dec) in total body water by 17%
(Inc/Dec) in extracellular body fluid by 40%
(Inc) in body fat by 35%
(Dec) in plasma volume by 8%
(Dec) in total body water by 17%
(Dec) in extracellular body fluid by 40%
What labs would you complete to Rule Out Alzheimer's Disease? (5)
1. CBC
2. Metabolic Panel
3. Vitamins B12 and Folate
4. RPR Test
5. TSH
Why would an RPR Test be completed to rule out Alzheimer's?
RPR Test is to help rule of Syphilis
, Brain imagining like a CT or MRI should be done in someone who is suspected of having
Alzheimer's, True or False.
True
these imaging studies are essential in order to rule out brain, pathology, or identify structural
abnormalities
What medication is Second Line for Adjunct Therapy for Alzheimer's disease?
Memantine
What's the initial dosing of Memantine?
Initial dose 5mg daily
What is the titration for Memantine?
Titrate 10mg daily, then 10mg twice daily over 4 weeks
What imaging is used to visualized the infarcts cause by Vascular Dementia?
CT or MRI of the brain
What's the etiology of Lewy Body Dementia?
Lewy bodies are abnormal clumps of a protein called Alpha synuclein that build up in the
neurons. The proteins damage the neurons and interfere with the availability of acetylcholine.
How do cholinesterase inhibitors help the symptoms of Lewy Body Dementia?
Cholinesterase inhibitors help by increasing the availability of acetylcholine
Charles is a 75-year-old man. He has been diagnosed with Alzheimer's disease. He is currently
presenting some new symptoms such as muscle stiffness and pill rolling tremor. What if the
following medications would be best to cater to his symptoms?
A. Donepezil
B. Rivastigmine
C. Galantamine
D. Levadopa
E. Memantine
D. Levadopa
This medication is best used to cater to patients presenting with Parkinson-like symptoms of
Lewy body Dementia
Comprehensive Review
Rapid progression or onset of Alzheimer's before age 80 is a red flag and the patient should be
referred to Neurology, True or False?
False
Rapid progression or onset of Alzheimer's before age 60 is a red flag
What is the First-Line medication used for Alzheimer's disease?
Cholinesterase Inhibitors
What's the MOA of the Cholinesterase Inhibitors?
Prevent the breakdown of acetylcholine, improving neurotransmissions.
What is the initial dose of Donepezil used for Alzheimer's? (What time of day)
Initial dose is 5mg at Bedtime
What is the Titration of Donepezil?
Increased to 10mg after 4-6 weeks
What is the max dose of Donepezil?
23mg/day
What is the initial dose of Galantamine?
4mg twice daily
What is the titration of Galantamine?
Extended release 8mg once daily
What is the initial dose of Rivastigmine?
The initial dose is 1.5mg
What is the dose is the dose of the transdermal patch of Rivastigmine? How often does it
need to be changed?
4.6mg changed every 24 hours
What are some side effects of Rivastigmine?
,Anorexia
Weight loss
Nausea and vomiting
Loss of appetite
Dehydration
Headaches
AV Block
What age is recommended for Elderly Patients get the Prevnar 13 Vaccination?
Age 65 and older
What age is recommended for Elderly Patients get the Pneumococcal Vaccination (PPSV23)?
Age 65 and older
What age is recommended for Elderly Patients get the Shingrix Vaccination?
Age 59 and older
How many doses are the Shingrix series?
2 doses
How many months apart should the Shingrix vaccine be given?
2-6 months apart
How often should an older adult get the influenza vaccine?
Annually (every fall)
How often should one get a Tdap Booster shot?
Booster every 10 years
Which of the follow are considered normal BMI range for older adults?
A. 20-25
B. 23-30
C. 30-45
B. 23-30
Malnutrition risk is considered > 5% weight loss in 1 month, True or False?
True
Malnutrition risk is considered > 10% weight loss in 10 months, True or False?
,False.
> 10% weight loss in 6 months
In how many second should an older adult be able to complete the Get Up and Go test?
< 12 seconds
What are the 4 main factors that alter drug distributions in older adults?
1. Increased body fat
2. Decreased lean body mass
3. Decreased body water
4. Reduced serum albumin
Fat soluble drugs accumulate in the adipose tissue leading to prolonged effects. True or False?
True
Hepatic Metabolism (Increases/Decreases) with age?
Decreases
Age Dependent Changes in Body Composition
(Inc/Dec) in body fat by 35%
(Inc/Dec) in plasma volume by 8%
(Inc/Dec) in total body water by 17%
(Inc/Dec) in extracellular body fluid by 40%
(Inc) in body fat by 35%
(Dec) in plasma volume by 8%
(Dec) in total body water by 17%
(Dec) in extracellular body fluid by 40%
What labs would you complete to Rule Out Alzheimer's Disease? (5)
1. CBC
2. Metabolic Panel
3. Vitamins B12 and Folate
4. RPR Test
5. TSH
Why would an RPR Test be completed to rule out Alzheimer's?
RPR Test is to help rule of Syphilis
, Brain imagining like a CT or MRI should be done in someone who is suspected of having
Alzheimer's, True or False.
True
these imaging studies are essential in order to rule out brain, pathology, or identify structural
abnormalities
What medication is Second Line for Adjunct Therapy for Alzheimer's disease?
Memantine
What's the initial dosing of Memantine?
Initial dose 5mg daily
What is the titration for Memantine?
Titrate 10mg daily, then 10mg twice daily over 4 weeks
What imaging is used to visualized the infarcts cause by Vascular Dementia?
CT or MRI of the brain
What's the etiology of Lewy Body Dementia?
Lewy bodies are abnormal clumps of a protein called Alpha synuclein that build up in the
neurons. The proteins damage the neurons and interfere with the availability of acetylcholine.
How do cholinesterase inhibitors help the symptoms of Lewy Body Dementia?
Cholinesterase inhibitors help by increasing the availability of acetylcholine
Charles is a 75-year-old man. He has been diagnosed with Alzheimer's disease. He is currently
presenting some new symptoms such as muscle stiffness and pill rolling tremor. What if the
following medications would be best to cater to his symptoms?
A. Donepezil
B. Rivastigmine
C. Galantamine
D. Levadopa
E. Memantine
D. Levadopa
This medication is best used to cater to patients presenting with Parkinson-like symptoms of
Lewy body Dementia
