Galen College
Q1. Which medication is classified as a nonopioid analgesic and
antipyretic?
A) Acetaminophen
B) Morphine
C) Fentanyl
D) Naloxone
Correct Answer: A) Acetaminophen
Rationale: Acetaminophen provides analgesic and antipyretic effects but
has minimal anti-inflammatory activity.
Q2. Which adverse effect is the major concern with excessive
acetaminophen use?
A) Ototoxicity
B) Hepatotoxicity
C) Hyperkalemia
D) Respiratory depression
Correct Answer: B) Hepatotoxicity
Rationale: Excessive acetaminophen can cause severe liver injury and
potentially acute liver failure.
Q3. Which patient statement requires further teaching about
acetaminophen?
A) “I will check combination medications for acetaminophen.”
B) “I will follow the recommended dose.”
C) “If one dose does not help, I can keep increasing the dose.”
D) “I will avoid taking multiple acetaminophen-containing products.”
Correct Answer: C) “If one dose does not help, I can keep increasing
the dose.”
Rationale: Increasing the dose independently can result in toxic
acetaminophen exposure and serious liver injury.
Q4. Which medication is classified as a salicylate?
A) Ibuprofen
B) Naproxen
,C) Acetaminophen
D) Aspirin
Correct Answer: D) Aspirin
Rationale: Aspirin is a salicylate that provides analgesic, antipyretic, anti-
inflammatory, and antiplatelet effects.
Q5. Which adverse effect is particularly associated with aspirin
therapy?
A) Gastrointestinal bleeding
B) Urinary retention
C) Hyperglycemia
D) Severe constipation
Correct Answer: A) Gastrointestinal bleeding
Rationale: Aspirin inhibits platelet aggregation and can irritate the
gastrointestinal mucosa, increasing bleeding risk.
Q6. Which patient should generally avoid aspirin unless specifically
directed by the provider?
A) Adult with osteoarthritis
B) Child or adolescent recovering from a viral illness
C) Adult with chronic stable hypertension
D) Adult with a tension headache
Correct Answer: B) Child or adolescent recovering from a viral
illness
Rationale: Aspirin use during certain viral illnesses in children and
adolescents is associated with Reye syndrome.
Q7. What is the primary therapeutic effect of low-dose aspirin in
many cardiovascular patients?
A) Bronchodilation
B) Platelet inhibition
C) Increased urine production
D) Thyroid replacement
Correct Answer: B) Platelet inhibition
Rationale: Aspirin irreversibly inhibits platelet aggregation and can reduce
arterial thrombotic events.
, Q8. Which finding may indicate salicylate toxicity?
A) Tinnitus
B) Bradycardia only
C) Severe hypothermia
D) Urinary retention
Correct Answer: A) Tinnitus
Rationale: Tinnitus is a classic early manifestation of salicylate toxicity.
Q9. Which laboratory result is especially concerning in a patient who
has taken a large amount of aspirin?
A) Decreased serum sodium only
B) Elevated salicylate level
C) Increased hemoglobin
D) Increased albumin
Correct Answer: B) Elevated salicylate level
Rationale: Measuring serum salicylate concentration helps determine the
severity of toxicity and guide treatment.
Q10. Which medication may interfere with the antiplatelet effect of
low-dose aspirin when taken regularly?
A) Acetaminophen
B) Ibuprofen
C) Loratadine
D) Guaifenesin
Correct Answer: B) Ibuprofen
Rationale: Regular ibuprofen use may interfere with aspirin's platelet-
inhibiting effect when dosing overlaps in certain circumstances.
Q11. Which class of medication includes ibuprofen and naproxen?
A) NSAIDs
B) Opioids
C) Anticholinergics
D) Anticoagulants
Correct Answer: A) NSAIDs