,NU 150 EXAM 2 Pharmacology Questions And Answers 2026/2027
Galen College
Q1. Which medication is a synthetic form of antidiuretic hormone
used to reduce excessive urination in diabetes insipidus?
A) Vasopressin
B) Levothyroxine
C) Prednisone
D) Methimazole
Correct Answer: A) Vasopressin
Rationale: Vasopressin promotes water reabsorption by the kidneys and can
be used to manage diabetes insipidus caused by inadequate antidiuretic
hormone activity.
Q2. Which finding indicates the desired therapeutic effect of
vasopressin in diabetes insipidus?
A) Increased urine output
B) Decreased urine output and reduced excessive thirst
C) Increased serum sodium
D) Increased dehydration
Correct Answer: B) Decreased urine output and reduced excessive thirst
Rationale: Vasopressin increases renal water reabsorption, reducing
excessive urinary losses and helping improve dehydration and intense thirst
associated with diabetes insipidus.
Q3. Which complication is associated with excessive vasopressin
administration?
A) Water intoxication
B) Severe dehydration
C) Hyperthyroidism
D) Hypoglycemia
Correct Answer: A) Water intoxication
Rationale: Excessive antidiuretic activity can cause excessive water
retention, dilutional hyponatremia, and fluid overload.
Q4. Which assessment is particularly important in a patient
receiving vasopressin?
,A) Fluid balance and cardiovascular status
B) Visual acuity only
C) Skin pigmentation only
D) Bowel sounds only
Correct Answer: A) Fluid balance and cardiovascular status
Rationale: Vasopressin affects water retention and vascular tone, so fluid
balance, blood pressure, cardiac status, and signs of water intoxication
require monitoring.
Q5. Which medication is a glucocorticoid?
A) Prednisone
B) Levothyroxine
C) Propylthiouracil
D) Vasopressin
Correct Answer: A) Prednisone
Rationale: Prednisone is a corticosteroid with glucocorticoid activity used to
suppress inflammation and modify immune responses.
Q6. Which condition may be treated with systemic glucocorticoids
such as prednisone?
A) Inflammatory disorders
B) Bacterial infection as sole therapy
C) Diabetes insipidus
D) Hypothyroidism
Correct Answer: A) Inflammatory disorders
Rationale: Glucocorticoids are used for inflammatory and immune-mediated
conditions such as asthma exacerbations, autoimmune disorders, and certain
inflammatory diseases.
Q7. Why should long-term prednisone generally not be stopped
abruptly?
A) It can cause acute insulin resistance
B) It may cause adrenal insufficiency because endogenous corticosteroid
production has been suppressed
C) It immediately causes hyperthyroidism
D) It permanently increases blood pressure
, Correct Answer: B) It may cause adrenal insufficiency because endogenous
corticosteroid production has been suppressed
Rationale: Prolonged glucocorticoid therapy suppresses the hypothalamic-
pituitary-adrenal axis, so gradual tapering may be required to allow adrenal
function to recover.
Q8. Which adverse effect is associated with prolonged
glucocorticoid therapy?
A) Hyperglycemia
B) Severe hypoglycemia
C) Increased bone density
D) Decreased infection risk
Correct Answer: A) Hyperglycemia
Rationale: Glucocorticoids increase hepatic glucose production and reduce
insulin sensitivity, which can raise blood glucose.
Q9. Which additional complication should the nurse monitor for
during prolonged prednisone therapy?
A) Increased susceptibility to infection
B) Increased platelet production
C) Complete suppression of appetite
D) Permanent bradycardia
Correct Answer: A) Increased susceptibility to infection
Rationale: Corticosteroids suppress immune and inflammatory responses,
increasing susceptibility to infection and potentially masking infection
symptoms.
Q10. Which medication is the drug of choice for replacement
therapy in hypothyroidism?
A) Levothyroxine
B) Methimazole
C) Propylthiouracil
D) Vasopressin
Correct Answer: A) Levothyroxine
Rationale: Levothyroxine is synthetic thyroid hormone used to replace
deficient thyroid hormone in hypothyroidism.
Galen College
Q1. Which medication is a synthetic form of antidiuretic hormone
used to reduce excessive urination in diabetes insipidus?
A) Vasopressin
B) Levothyroxine
C) Prednisone
D) Methimazole
Correct Answer: A) Vasopressin
Rationale: Vasopressin promotes water reabsorption by the kidneys and can
be used to manage diabetes insipidus caused by inadequate antidiuretic
hormone activity.
Q2. Which finding indicates the desired therapeutic effect of
vasopressin in diabetes insipidus?
A) Increased urine output
B) Decreased urine output and reduced excessive thirst
C) Increased serum sodium
D) Increased dehydration
Correct Answer: B) Decreased urine output and reduced excessive thirst
Rationale: Vasopressin increases renal water reabsorption, reducing
excessive urinary losses and helping improve dehydration and intense thirst
associated with diabetes insipidus.
Q3. Which complication is associated with excessive vasopressin
administration?
A) Water intoxication
B) Severe dehydration
C) Hyperthyroidism
D) Hypoglycemia
Correct Answer: A) Water intoxication
Rationale: Excessive antidiuretic activity can cause excessive water
retention, dilutional hyponatremia, and fluid overload.
Q4. Which assessment is particularly important in a patient
receiving vasopressin?
,A) Fluid balance and cardiovascular status
B) Visual acuity only
C) Skin pigmentation only
D) Bowel sounds only
Correct Answer: A) Fluid balance and cardiovascular status
Rationale: Vasopressin affects water retention and vascular tone, so fluid
balance, blood pressure, cardiac status, and signs of water intoxication
require monitoring.
Q5. Which medication is a glucocorticoid?
A) Prednisone
B) Levothyroxine
C) Propylthiouracil
D) Vasopressin
Correct Answer: A) Prednisone
Rationale: Prednisone is a corticosteroid with glucocorticoid activity used to
suppress inflammation and modify immune responses.
Q6. Which condition may be treated with systemic glucocorticoids
such as prednisone?
A) Inflammatory disorders
B) Bacterial infection as sole therapy
C) Diabetes insipidus
D) Hypothyroidism
Correct Answer: A) Inflammatory disorders
Rationale: Glucocorticoids are used for inflammatory and immune-mediated
conditions such as asthma exacerbations, autoimmune disorders, and certain
inflammatory diseases.
Q7. Why should long-term prednisone generally not be stopped
abruptly?
A) It can cause acute insulin resistance
B) It may cause adrenal insufficiency because endogenous corticosteroid
production has been suppressed
C) It immediately causes hyperthyroidism
D) It permanently increases blood pressure
, Correct Answer: B) It may cause adrenal insufficiency because endogenous
corticosteroid production has been suppressed
Rationale: Prolonged glucocorticoid therapy suppresses the hypothalamic-
pituitary-adrenal axis, so gradual tapering may be required to allow adrenal
function to recover.
Q8. Which adverse effect is associated with prolonged
glucocorticoid therapy?
A) Hyperglycemia
B) Severe hypoglycemia
C) Increased bone density
D) Decreased infection risk
Correct Answer: A) Hyperglycemia
Rationale: Glucocorticoids increase hepatic glucose production and reduce
insulin sensitivity, which can raise blood glucose.
Q9. Which additional complication should the nurse monitor for
during prolonged prednisone therapy?
A) Increased susceptibility to infection
B) Increased platelet production
C) Complete suppression of appetite
D) Permanent bradycardia
Correct Answer: A) Increased susceptibility to infection
Rationale: Corticosteroids suppress immune and inflammatory responses,
increasing susceptibility to infection and potentially masking infection
symptoms.
Q10. Which medication is the drug of choice for replacement
therapy in hypothyroidism?
A) Levothyroxine
B) Methimazole
C) Propylthiouracil
D) Vasopressin
Correct Answer: A) Levothyroxine
Rationale: Levothyroxine is synthetic thyroid hormone used to replace
deficient thyroid hormone in hypothyroidism.
